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Strayer N**, Zhang S**, Yao L**, Vessels T, Bejan CA, Hsi RS, Shirey-Rice JK, Balko JM, Johnson DB, Phillips EJ, Bick A, Edwards TL, Velez Edwards DR, Pulley JM, Wells QS, Savona MR, Cox NJ, Roden DM, Ruderfer DM, Xu Y*. Interactive network-based clustering and investigation of multimorbidity association matrices with associationSubgraphs. Bioinformatics (Oxford, England). 2023 Jan 1;39(39).
Abstract
Making sense of networked multivariate association patterns is vitally important to many areas of high-dimensional analysis. Unfortunately, as the data-space dimensions grow, the number of association pairs increases in O(n2); this means that traditional visualizations such as heatmaps quickly become too complicated to parse effectively.