ColonMap

Colon Molecular Atlas Project: An Integrative Single-Cell Atlas of Host and Microenvironment in Colorectal Neoplastic Transformation

VBDCC unit: Data Management

Project homepage: humantumoratlas.org/hta11

Biostatistics faculty on this project:

  • Yu Shyr, Data Analysis Unit Biostatistics Lead
  • Qi Liu, Data Analysis Unit Bioinformatics Lead
  • Lynne Berry, Co-Investigator, Data Distribution
  • Simon Vandekar, Co-Investigator, Image Analysis
  • Quanhu Sheng, Co-Investigator, Software Engineering 

Press:

ColonMap is a pre-cancer atlas (PCA) project funded under U2C CA233291 (National Cancer Institute) from 2018 to 2023. For this project, we designed, developed, implemented, and maintained a complex, integrated electronic study, participant, and specimen management system with extensive automated features and functionality to support participant recruitment and disposition on the study; electronic capture of all participant-level, procedure-level, and specimen-level data; and biospecimen tracking. This management system greatly facilitates the study recruitment process, as well as the tracking of biospecimen collection and use.

Further, the integration of biospecimen-level data with participant-level clinical and epidemiological data allows for ready identification of specimens of interest for any particular assay or experiment based on study participant covariates. User convenience is emphasized, with many automated features and functions, including automated ETL (extraction, transformation, and loading) from multiple other data systems such as the electronic health record (EHR), the participant survey system, and the specimen repository database, to provide a single, fully integrated data source for this study.

Additional information: