Participation Requirements

Is the AHEAD study right for me?

 You should join the AHEAD study if:

  • You are interested in participating in a research trial that involves regular drug administration (once or twice a month) of an investigational study drug (BAN2401) or placebo for up to 4 years.

  • You are willing to come to the study site (clinic) on a regular basis to participate in the questionnaires, laboratory tests and imaging scans or up to 4 years.

  • You are willing to learn your amyloid results (intermediate, elevated, or not elevated) which may relate to your risk of developing AD dementia.

  • You have a trusted family member or friend (called a “study partner”) who can accompany you to a few key study visits or be available by phone (both now and for the 4 years of the research study, if you qualify). Your study partner will answer questions about your memory and thinking and otherwise be available to assist you. They should have regular contact with you – about once a week or so. This can be in-person, phone or electronic contact.

Participation

What happens during study visits?

A number of assessments will be performed during each study visit. A description of some of the infusionassessments is given below:

  • You will be asked questions about your memory and thinking abilities, your emotional and psychological state, and how well you can carry out everyday activities.

  • Your study partner will also be asked a number of questions about how you carry out everyday activities. Your study partner may answer these questions by phone once a year.

  • You’ll be asked about any medications you’re taking (including non-prescription medicines, supplements, and herbal remedies). In general, you will be allowed to continue to take any of these medications, supplements, and herbal remedies as long as they are not likely to affect the investigational treatment. You will also be asked about any medications you may have taken in between study visits (ex. cold/allergy or pain medications).

  • You’ll be asked about your general health, including any illnesses or complaints you’ve had or have.