Researchers at Vanderbilt University Medical Center and their colleagues are a step closer to developing a broadly effective antibody treatment against the three major Ebola viruses that cause lethal disease in humans. Reporting July 17 in the journal Immunity, they describe the isolation of two potent monoclonal antibodies from human survivors of Ebola virus disease that, in cell culture studies, efficiently neutralized the Zaire, Sudan and Bundibugyo ebolaviruses.

Finally, anti-bodies to three major Ebola viruses have now been developed. Researchers at Vanderbilt University Medical Center are a step closer to developing a broadly effective antibody treatment against these viruses that cause the lethal disease in humans. Researchers found that the isolation of two potent monoclonal antibodies from human survivors of Ebola virus disease in cell culture studies efficiently neutralized the Zaire, Sudan and Bundibugyo Ebola viruses.