-
Wiese AD, Griffin MR, Schaffner W, Stein CM, Greevy RA, Mitchel EF, Grijalva CG. Long-acting opioid use and the risk of serious infections: a retrospective cohort study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2018 Sep 15.
Abstract
Although evidence from animal and human studies indicates opioid analgesics increase susceptibility to infections, it is unclear whether the risk varies by specific opioid. We compared the risk of serious infection among patients initiating long-acting opioid analgesics with and without previously reported immunosuppressive properties.