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Grijalva CG. Changes in otitis media episodes and pressure equalization tube insertions among young children following introduction of the 13-valent pneumococcal conjugate vaccine: A birth-cohort based study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2019 Feb 16.
Abstract
The impact of 13-valent pneumococcal conjugate vaccine (PCV13) introduction on the occurrence of first and subsequent otitis media (OM) episodes in early childhood is unclear. We compared the risk of OM episodes among children age 2 years before and after PCV13 introduction accounting for the dependence between OM episodes.