Race/ethnicity difference in the pharmacogenetics of bilirubin-related atazanavir discontinuation.

Leger P, Chirwa S, Nwogu JN, Turner M, Richardson DM, Baker P, Leonard M, Erdem H, Olson L, Haas DW. Race/ethnicity difference in the pharmacogenetics of bilirubin-related atazanavir discontinuation. Pharmacogenetics and genomics. 2018 Jan;28(28). 1-6. PMID: 29117017 [PubMed] PMCID: PMC5726942 NIHMSID: NIHMS913375.

Abstract

Atazanavir causes plasma indirect bilirubin to increase. We evaluated associations between Gilbert's polymorphism and bilirubin-related atazanavir discontinuation stratified by race/ethnicity.