Association between First Trimester Antidepressant Use and Risk of Spontaneous Abortion.

Wu P, Velez Edwards DR, Gorrindo P, Sundermann AC, Torstenson ES, Jones SH, Chan RL, Hartmann KE. Association between First Trimester Antidepressant Use and Risk of Spontaneous Abortion. Pharmacotherapy. 2019 Sep;39(39). 889-898. PMID: 31278762 [PubMed] PMCID: PMC6736709 NIHMSID: NIHMS1040188.

Abstract

The potential for maternal antidepressant use to influence the risk of spontaneous abortion, one of the most important adverse pregnancy outcomes, is not clear. We aimed to assess whether first trimester antidepressant exposure was associated with an increased risk of spontaneous abortion.