Neil Sprenkle

Graduate Student
Molecular Pathology & Immunology Graduate Program
Lab Phone
615-875-6166

More Information

https://www.linkedin.com/in/neil-sprenkle-ab441274

Neil is graduate student in the Department of Pathology, Microbiology, and Immunology. He completed his BS at West Virginia University in 2015, where he double majored in Biochemistry and Animal and Nutritional Sciences. He also completed his MS in Biomedical Science at West Virginia University in 2017. Neil joined the Pua Lab in 2018, and his research project focuses on how the miR-23-27-24 clusters regulate macrophage function.

Research Information

I am investigating how miRNAs from the miR-23-27-24 clusters regulate macrophage function in obesity, and whether targeting these molecules can improve systemic metabolic homeostasis.

Select Publications on PubMed.gov

Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses.

Increasing palmitic acid intake enhances milk production and prevents glucose-stimulated fatty acid disappearance without modifying systemic glucose tolerance in mid-lactation dairy cows.

Endoplasmic reticulum stress and inflammation in the central nervous system.

Lab Website
https://www.vumc.org/pua-lab/