Warren D. Taylor, M.D., MHSc, James G Blakemore Professor of Psychiatry, served as lead author of a new publication proposing how dysfunction in the dopamine system may influence depression in older adults. This may influence risk for depression but also serve as a new target for treatment. The manuscripts provides the rationale for a current multi-site study being conducted at Vanderbilt examining the effect of levodopa (Sinemet) on late-life depression. The paper appears in the journal Molecular Psychiatry.