Immunometabolism and Metabolic Diseases Researchers

The finding that obesity, diabetes, and cardiovascular diseases are driven by inflammation and that metabolic pathways influence immune cell differentiation and function has led to the field of Immunometabolism.  This new field seeks to understand links between metabolism and inflammation.  Working with the Vanderbilt Diabetes Research and Training Center (VDRTC), VCI member study how metabolic pathways contribute to the pathogenesis of the Metabolic Syndrome and how metabolic pathways modulate immunity.

Ruben Martinez Barricarte, Ph.D

Ruben Martinez Barricarte, Ph.D

Assistant Professor of Medicine

Assistant Professor of Pathology, Microbiology and Immunology

Immunogenetics, primary immunodeficiencies, inborn errors of Immunity and infectious diseases

Julia Bohannon, Ph.D.

Julia Bohannon, Ph.D.

Associate Professor of Anesthesiology

Associate Professor of Pathology, Microbiology and Immunology

Innate immune responses to infection in immunocompromised hosts

Rachel Bonami, Ph.D.

Rachel Bonami, Ph.D.

Assistant Professor of Medicine

Assistant Professor of Pathology, Microbiology, and Immunology

B cell, T cell, Autoimmunity, Type 1 Diabetes, Myositis, Sjogren's Syndrome, Immune Checkpoint Inhibitor-induced Autoimmunity

Mark Boothby, M.D., Ph.D

Mark Boothby, M.D., Ph.D.

Professor of Pathology, Microbiology and Immunology

Professor of Medicine

Signal transduction, transcription regulation mechanisms

 

Mariana Xavier Byndloss, D.V.M, Ph.D.

Mariana Xavier Byndloss, D.V.M., Ph.D.

Assistant Professor of Pathology, Microbiology and Immunology

Linking gut microbiota, host metabolism, and disease

Katherine Cahill, M.D.

Katherine Cahill, M.D.

Assistant Professor of Medicine

Aspirin-exacerbated Respiratory Disease (AERD), Adult-onset Asthma, NSAID drug allergy, Chronic Rhinosinusitis with Nasal Polyps,  Eicosanoid Biology, Cells and Mediators of Allergic Inflammation

 

James E. Cassat, M.D., Ph.D.

James E. Cassat, M.D., Ph.D.

Assistant Professor of Pediatrics

Associate Professor of Pathology, Microbiology and Immunology

Assistant Professor of Biomedical Engineering

Associate Director, Institute for Infection, Immunology and Inflammation

Interaction between host and pathogen during invasive bacterial infections

 

Sung Hoon Cho, Ph.D.

Sung Hoon Cho, Ph.D.

Research Assistant Professor of Pathology, Microbiology and Immunology

Immune response, cellular metabolism & tumor progression

 

Jim Connelly, M.D.

Jim Connelly, M.D.

Assistant Professor of Pediatrics

Primary Immune Deficiency, Bone Marrow Failure, Neutropenia, Sickle Cell Disease

 

C. Buddy Creech, M.D., M.P.H.

C. Buddy Creech, M.D., M.P.H.

Professor of Pediatrics

Edie Carell Johnson Chair in Pediatrics

 Clinical and Translational Research in S. aureus, Human immune response to staphylococcal infections, Staphylococcal vaccine development

 

Leslie J. Crofford, M.D.

Leslie Crofford, M.D.

Professor of Medicine

Professor of Pathology, Microbiology and Immunology

Director, Division of Rheumatology & Immunology

Wilson Family Chair in Medicine

Innate and acquired immunity in inflammatory arthritis, myositis, scleroderma, fibromyalgia, pain

 

Amanda Doran, M.D., Ph.D.

Amanda Doran, M.D., Ph.D.

Assistant Professor of Medicine 

Assistant Professor of Molecular Physiology & Biophysics

Assistant Professor of Pathology, Microbiology and Immunology

Cholesterol, Lipids, Familial Hypercholesterolemia, Statin Intolerance

 

Jane Freedman, M.D.

Jane Freedman, M.D.

Interim Chair of the Department of Medicine

Professor of Medicine

Gladys Parkinson Stahlman Chair in Cardiovascular Research

Immunity, infection, and inflammation on atherothrombotic disease

Alyssa H. Hasty, Ph.D.

Alyssa H. Hasty, Ph.D.

Cornelius Vanderbilt Chair in Molecular Physiology and Biophysics

Mechanisms by which obesity increases risk for disease

 

Jonathan M. Irish, Ph.D.

Jonathan M. Irish, Ph.D.

Assistant Professor of Cell & Developmental Biology

Assistant Professor of Pathology, Microbiology and Immunology

Cancer, precision medicine, computational biology, machine learning, cell signaling, chemical biology, single cell tools

 

Spyros Kalams, M.D.

Spyros Kalams, M.D.

Professor of Medicine

Professor of Pathology, Microbiology and Immunology

Cellular immune responses directed against viral and bacterial pathogens

 

Annet Kirabo, D.V.M., Ph.D.

Annet Kirabo, D.V.M., Ph.D. 

Associate Professor of Medicine

Associate Professor of Molecular Physiology & Biophysics

Cardiovascular disease, Hypertension, Dendritic cells, Neo-antigens, Isolevuglandins

 

John Koethe, M.D.

John Koethe, M.D. 

Associate Professor of Medicine

Interaction of HIV infection and nutritional host factors in risk of metabolic disease

 

Amy S. Major, Ph.D.

Amy S. Major, Ph.D.

Associate Professor of Medicine

Associate Professor of Pathology, Microbiology and Immunology

Immunological mechanisms of autoimmunity in atherosclerosis

 

Janet Markle, Ph.D.

Janet Markle, Ph.D.

Assistant Professor of Pathology, Microbiology and Immunology

Inborn errors of immunity, Molecular and cellular immunology, pediatric immune-mediated diseases

 

Mona Mashayekhi, M.D., Ph.D.

Mona Mashayekhi, M.D., Ph.D.

Assistant Professor of Medicine

Gestational diabetes, Endocrine disorders of pregnancy

 

Denis Mogilenko, Ph.D.

Denis Mogilenko, Ph.D.

Assistant Professor of Medicine 

Assistant Professor of Pathology, Microbiology and Immunology 

Assistant Professor of Pathology, Microbiology and Immunology

Immunometabolism, Molecular Biology, Systems Biology, Computational Biology, Cancer Biology, Obesity, Aging,

 

Daniel J. Moore, M.D., Ph.D.

Daniel J. Moore, M.D., Ph.D.

Assistant Professor of Pediatrics

Assistant Professor of Pathology, Microbiology and Immunology

Immune regulation in autoimmunity and transplantation

 

Dawn C. Newcomb, Ph.D.

Dawn C. Newcomb, Ph.D.

Assistant Professor of Medicine

Assistant Professor of Pathology, Microbiology and Immunology

Estrogen, testosterone, sex hormones, T cells, innate lymphoid cells, asthma, allergy

 

Michelle Ormseth, M.D.

 

Michelle Ormseth, M.D.

Assistant Professor of Medicine

Cardiovascular disease and small RNAs as biomarkers and modifiers of disease in patients with rheumatic diseases.

 

Anna Patrick, MD, PhD

Anna Patrick, M.D., Ph.D.

Assistant Professor, Department of Pediatrics

Juvenile Idiopathic Arthritis, Autoimmune Disease, Autoinflammatory Disease, Immunology, Genetics

Elizabeth Phillips, M.D.

Elizabeth Phillips, M.D.

Professor of Medicine

Professor of Dermatology

John A. Oates Chair in Clinical Research

Professor of Pathology, Microbiology and Immunology

Professor of Pharmacology

HLA, T-cell Immunology, Immunogenomics, Pharmacogenomics, Drug Hypersensitivity, SJS/TEN, Adverse Drug Reactions

 

Heather Pua, M.D., Ph.D.

Heather Pua, M.D., Ph.D.

Assistant Professor of Pathology, Microbiology and Immunology

Lung, miRNA, exRNA (extracellular RNA), extracellular vesicles, allergy, asthma, Th2

 

Marjan Rafat, Ph.D.

Marjan Rafat, Ph.D.

Assistant Professor of Chemical & Biomolecular Engineering

Assistant Professor of Radiation Oncology

Effects of radiation and surgery on tumor and immune cell migration, the molecular profiles of tissues wounded from therapy, and the biomechanical properties of tissues following therapy

 

Jeffrey C. Rathmell, Ph.D.

Jeffrey C. Rathmell, Ph.D.

Director, Vanderbilt Center for Immunobiology

Professor of Pathology, Microbiology and Immunology

Professor of Molecular Physiology & Biophysics

Cornelius Vanderbilt Chair in Immunobiology

T cell metabolism in inflammation and anti-tumor immunity

 

Michael Savona, MD

Michael Savona, M.D.

Professor of Medicine

Hematology, Cellular Therapy and Stem Cell Transplantation

C. Henrique Serezani, Ph.D.

C. Henrique Serezani, Ph.D.

Assistant Professor of Medicine, Infectious Disease

Assistant Professor of Pathology, Microbiology and Immunology

Understanding host defense in pre-existing inflammatory conditions

 

Anil Shanker, Ph.D.

Anil Shanker, Ph.D.

Professor of Pathology, Microbiology and Immunology

Cornelius Vanderbilt Chair in Pathology, Microbiology and Immunology

Biochemistry and molecular biology of HIV infection; Antiviral mechanisms

 

Matthew Stier, M.D., Ph.D.

Matthew Stier, M.D., Ph.D.

Fellow, Division of Allergy, Pulmonary and Critical Care Medicine

Immunology and immunometabolism in critical illness, hemorrhagic shock, septic shock, and ARDS.
 

Luc Van Kaer, Ph.D.

Luc Van Kaer, Ph.D.

Elizabeth and John Shapiro Chair

Professor of Pathology, Microbiology and Immunology

Role of innate-type regulatory lymphocytes in health and chronic inflammatory diseases

 

Kasey Vickers, Ph.D.

Kasey Vickers, Ph.D.

Associate Professor of Medicine

Associate Professor of Molecular Physiology & Biophysics

Assistant Professor of Pathology, Microbiology and Immunology

MicroRNAs and other sRNA-mediated gene regulation in cholesterol, glucose, lipid and lipoprotein metabolism

 

Celestine Wanjalla, M.D., Ph.D.

Celestine Wanjalla, M.D., Ph.D.

Assistant Professor of Medicine

Virus-specific immune responses, chronic inflammation and aging

 

Nicole L. Ward, Ph.D.

Nicole L. Ward, Ph.D.

Vice Chair for Research, Department of Dermatology

Professor of Dermatology

Professor of Pathology, Microbiology and Immunology

Psoriasis, psoriatic arthritis (PsA), osteogenesis imperfecta (OI), lupus, hidradenitis suppurativa (HS), other inflammatory skin diseases, multi-‘omics, microbiome, and skin disease co-morbidities.

 

John Wilson, Ph.D.

John T. Wilson, Ph.D.

Assistant Professor, Chemical & Biomolecular Enginering

Assistant Professor, Biomedical Engineering

Polymer science, nanotechnology, immunobiology, colloid and surface engineering, cell engineering, and drug delivery

 

Keith T. Wilson, M.D.

Keith T. Wilson, M.D.

Thomas F. Frist Sr. Chair in Medicine

Professor of Medicine

Professor of Pathology, Microbiology and Immunology

Host immune response to the gastric pathogen Helicobacter pylori

 

Lan Wu, M.D.

Lan Wu, M.D.

Research Associate Professor of Pathology, Microbiology and Immunology

Interactions between the immune and metabolic systems, whole body metabolism

 

Elma Zaganjor, Ph.D.

Elma Zaganjor, Ph.D.

Assistant Professor of Molecular Physiology & Biophysics

Mitochondrial function and metabolism on cell fate decisions and their relevance to physiology

 

Sandra S. Zinkel, M.D., Ph.D.

Sandra S. Zinkel, Ph.D., M.D.

Associate Professor of Medicine

Associate Professor of Cancer Biology

Mechanisms by which normal and malignant cells regulate programed cell death or apoptosis following DNA damage

 

Back to Top of page

 

Back to Research Interest Areas