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Naji Abrumad, M.D.
SurgeryAssociate DirectorVanderbilt Digestive Diseases Research Center (VDDRC)Research Interests: Mechanisms involved in improved glucose handling following bariatric surgery; role of the omentum in the treatment of morbid obesity
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Research Interests: Understanding the basic mechanisms regulating cellular longevity in health and metabolic disease
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Research Interests: Elucidating gut-brain interactions that regulate body weight and energy homeostasis
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Research Interests: Characterization of the molecular mechanism of action of Prostaglandin E2 (PGE2) and determination of the structure-function relationships of the PGE2 receptors
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Research Interests: The sodium iodide symporter (NIS): structure, transport mechanism, regulation, and roles in physiology, pathophysiology and public health
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Research Interests: The regulation of liver glucose production and storage by hormones, neural mediators, and metabolites
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Research Interests: Biochemical mechanisms that regulate body weight and insulin sensitivity
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Research Interests: Understanding how nutritional and other environmental factors affect pancreatic islet cell function and proliferation
Research Information
Lab Website -
Research Interests: Diabetes and bariatric surgery
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Research Interests: Molecular mechanisms underpinning vesicle-mediated protein transport and membrane biogenesis
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Research Interests: Immune-mediated mechanisms by which obesity increases risk of disease
Lab website: https://lab.vanderbilt.edu/hasty-lab/
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Research Interests: Elucidating insulin-mediated molecular mechanisms that regulate mitochondrial morphology and molecular transfer with the ER
Lab website: https://lab.vanderbilt.edu/hinton-lab/
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J. Matthew Luther, M.D.
MedicineAssociate DirectorVDRC Metabolic Physiology Shared Resource (MPSR)Research Interests: Contribution of aldosterone and mineralocorticoid receptor to insulin resistance, metabolic syndrome, and inflammation
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Owen McGuiness, Ph.D.
Molecular Physiology and BiophysicsDirectorVDRC Analytical Services CoreResearch Interests: Regulation of metabolic responses to inflammation: Interaction with nutrition
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Kevin Niswender, M.D., Ph.D.
MedicineDirectorDiabetes and Endocrinology Postdoctoral (DEP) Training ProgramDirectorVDRC Metabolic Physiology Shared Resource (MPSR)Research Interests: Development of novel treatments for diabetes by merging human genetics with drug discovery
Lab website: https://www.vumc.org/kd-niswender-lab/niswender-lab-mission
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Richard O'Brien, Ph.D.
Molecular Physiology and BiophysicsDirectorMolecular Endocrinology Training Program (METP)Research Interests: The regulation of insulin secretion with a focus on two proteins, G6PC2 and ZnT8
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John Stafford, M.D., Ph.D.
MedicineMolecular Physiology and BiophysicsDirectorVanderbilt Student Research Training Program (SRTP)Research Interests: Defining the mechanisms for sex differences in dyslipidemia, fatty liver and atherosclerosis using animal models
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Research Interests: Small RNA-mediated gene regulation in lipid and lipoprotein metabolism; microRNA communication and systemic homeostasis
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David Wasserman, Ph.D.
Molecular Physiology and BiophysicsDirectorMouse Metabolic Phenotyping CenterResearch Interests: Delineating the role of insulin and integrin signaling pathways in the control of metabolism in health and diabetes
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Jamey Young, Ph.D.
Chemical and Biomolecular EngineeringMolecular Physiology and BiophysicsDirectorIntegrated Training in Engineering and Diabetes (ITED) ProgramResearch Interests: Metabolic engineering; systems biology; diabetes, obesity and metabolic disorders; tumor metabolism; autotrophic metabolism; cell culture engineering
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