The fields of infection biology, immunobiology and inflammation research is varied and ever-expanding. Researchers the world over are making discoveries that contribute greatly to our collective understanding of health and disease. VI4 is committed to providing our members, students, and community resources to aid in knowledge-building in these core VI4 research areas. Please check out our current curated recommended reading list below from scientists across the country!
Recommended Reading - March & April 2024
VI4 Curation Team
- Dopamine transients follow a striatal gradient of reward time horizons. Mohebi A, et al. in Nature Neuroscience, February 6, 2024
- Bacteriophage infection and killing of intracellular Mycobacterium abscessus. Schmalstig A, et al. in mBio, December 7, 2023
- ADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation. Hu Shi-Bin, Et al. in Molecular Cell, November 2, 2023
- Long 3'UTRs predispose neurons to inflammation by promoting immunostimulatory double-stranded RNA formation. Dorrity T, et al. in Science Immunology, October 27, 2023
- Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity. Eshleman E, et al. in Cell Immunity, February 1, 2024
Recommended Reading - May & June 2024
VI4 Curation Team
- Histones with an unconventional DNA-binding mode in vitro are major chromatin constituents in the bacterium Bdellovibrio bacteriovorus Mohebi A, et al. in Nature Microbiology, October 9, 2023
- Mass Spectrometry Imaging and Histology for the Analysis of Budding Intestinal Organoids. Sekera E, et al. in Analytical Chemistry, March 1, 2024
- Genome-wide profiling of Hfq-bound RNAs reveals the iron-responsive small RNA RusT in Caulobacter crescentus. Vogt L, et al. in mBio, March 21, 2024
- Assessment of the Cutaneous Hormone Landscapes and Microbiomes in Vulvar Lichen Sclerosus. Pyle H, et al. in Journal of Investigative Dermatology, February 17, 2024
- HtrA, fatty acids, and membrane protein interplay in Chlamydia trachomatis to impact stress response and trigger early cellular exit. Stange N, et al. in Journal of Bacteriology, March 6, 2024
Recommended Reading - January & February 2024
VI4 Curation Team
- Synthetic Glycans Reveal Determinants of Antibody Functional Efficacy against a Fungal Pathogen. Crawford C, et al. in ACS Infectious Diseases, October 19, 2023
- Emapalumab for the treatment of refractory cytokine release syndrome in pediatric patients. Schuelke M, et al. in Blood Advances, September 18, 2023
- Molecular jackhammers eradicate cancer cells by vibronic-driven action. Ayala-Orozco C, et al. in Nature Chemistry, December 19, 2023
- Kupffer cell–like syncytia replenish resident macrophage function in the fibrotic liver. Peiseler M, et al. in Science, September 9, 2023
- A geometry-based approach to make viable-cell counting easy and cheap. Meyer C, et al. in Nature Microbiology, November 22, 2023
Recommended Reading - December 17th, 2023
VI4 Curation Team
- Probiotic-guided CAR-T cells for solid tumor targeting. Vincent R, et al. in Science, October 12, 2023
- A Candida auris–specific adhesin, Scf1, governs surface association, colonization, and virulence. Santana D, et al. in Science, September 28, 2023
- E-selectin-mediated rapid NLRP3 inflammasome activation regulates S100A8/S100A9 release from neutrophils via transient gasdermin D pore formation. Peruenster M, et al. in Nature Immunology, October 30, 2023
- Selection of a de novo gene that can promote survival of Escherichia coli by modulating protein homeostasis pathways. Idan Frumkin & Michael T. Laub. in Nature Ecology & Evolution, November 9, 2023
- Discovery of antibiotics that selectively kill metabolically dormant bacteria. Zheng E, et al . in PNAS, November 28, 2023
Recommended Reading - October 8th, 2023
VI4 Curation Team
- ApoE isoform– and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy. Seo DO, et al. in Science, January 13, 2023
- Heteroresistance to cefepime– taniborbactam in metallo-β-lactamaseencoding Enterobacterales. Weiss D, et al. in The Lancet, July 5, 2023
- Effect of Micro-Patterned Mucin on Quinolone and Rhamnolipid Profiles of Mucoid Pseudomonas aeruginosa under Antibiotic Stress. Bohn, P W, et al. in ACS Infectious Diseases, December 13, 2022
- Systemic application of bone-targeting peptidoglycan hydrolases as a novel treatment approach for staphylococcal bone infection. Keller A, et al. in mBio, September 28, 2023
- Variant STAT4 and Response to Ruxolitinib in an Autoinflammatory Syndrome. Baghdassarian H, et al. in The New England Journal of Medicine, June 15, 2023
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Recommended Reading - August 8th, 2023
VI4 Curation Team
- The enteric nervous system relays psychological stress to intestinal inflammation. Schneider K, et al. in Cell, May 5, 2023
- Viriforms—A New Category of Classifiable Virus-Derived Genetic Elements. Kuhn J & Koonin E. in Biomolecules, February 13, 2023
- De novo evolution of macroscopic multicellularity. Bozdag G. O, et al. in Nature, May 10, 2023
- Droplet Tn-Seq identifies the primary secretion mechanism for yersiniabactin in Yersinia pestis. Price, S, et al. in EMBO Reports, July 28, 2023
- Ectocytosis renders T cell receptor signaling self-limiting at the immune synapse. Stinchcombe J, et al. in Science, May 23, 2023
Recommended Reading - July 9th, 2023
VI4 Curation Team
- Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections. Buckley, P et al. in Cell Host & Mircobe, May 10, 2023
- Neutrophil metabolomics in severe COVID-19 reveal GAPDH as a suppressor of neutrophil extracellular trap formation. Li Y, et al. in Nature Communications, May 5, 2023
- Age-induced alterations of granulopoiesis generate atypical neutrophils that aggravate stroke pathology . Gullotta G, et al. in Nature Immunology, May 15, 2023
- Infection leaves a genetic and functional mark on the gut population of a commensal bacterium. Tawk C, et al. in Cell Host & Microbe, May 10, 2023
- Mirusviruses link herpesviruses to giant viruses. Gaia M, et al. in Nature, April 19, 2023
Recommended Reading - June 4th, 2023
VI4 Curation Team
- Role of Caspases and Gasdermin A during HSV-1 Infection in Mice. Li L, et al. in Viruses, September 13, 2022
- S+C121:C124tunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes. Culemann S, et al. in Journal of Experimental Medicine, March 28, 2023
- Profiling the human intestinal environment under physiological conditions. Shalon D, Et al. in Nature, May 10, 2023
- Exogenously Scavenged and Endogenously Synthesized Heme Are Differentially Utilized by Mycobacterium tuberculosis. Donegan R, et al. in Microbiology Spectrum, September 28, 2022
- Spatial transcriptome uncovers rich coordination of metabolism in E. coli K12 biofilm. Wang T, et al. in Nature Chemical Biology, April 13, 2023
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Recommended Reading - February 5th, 2023
VI4 Curation Team
- Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation. Hata M, et al. in Science, January 6, 2023
- Functional T cells are capable of supernumerary cell division and longevity. Soerens A, et al. in Nature, December 5, 2022
- Chlamydia repurposes the actin-binding protein EPS8 to disassemble epithelial tight junctions and promote infection. Dolat L, et al. in Cell Host & Microbe, December 14, 2022
- Gut colonization by Proteobacteria alters host metabolism and modulates cocaine neurobehavioral responses. Cuesta S, et al. in Cell Host & Microbe, November 9, 2022
- Fetal and maternal NLRP3 signaling is required for preterm labor and birth. Motomura K, et al. in The Journal of Clinical Investigation Insights, August 22, 2022
Recommended Reading - January 15th, 2023
VI4 Curation Team
- Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus. Mackensen A, et al. in Nature Medicine, September 15, 2022
- Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses. Hagan T, et al. in Nature Immunology, October 21, 2022
- Engineered cell entry links receptor biology with single-cell genomics. Yu B, et al. in Cell, December 22, 2022
- Mycobiota and diet-derived fungal xenosiderophores promote Salmonella gastrointestinal colonization. Santus W, et al. in Nature Microbiology, November 21, 2022
- Epithelial HNF4A shapes the intraepithelial lymphocyte compartment via direct regulation of immune signaling molecules. Lei X, et al. in Journal of Experimental Medicine, July 6, 2022