The fields of infection biology, immunobiology and inflammation research is varied and ever-expanding. Researchers the world over are making discoveries that contribute greatly to our collective understanding of health and disease. VI4 is committed to providing our members, students, and community resources to aid in knowledge-building in these core VI4 research areas. Please check out our current curated recommended reading list below from scientists across the country!
Recommended Reading - November 6th, 2022
- TCF-1 promotes chromatin interactions across topologically associating domains in T cell progenitors. Wang W, et al. in Nature Immunology, June 20, 2022
- Induced pluripotent stem cells display a distinct set of MHC I-associated peptides shared by human cancers. Aavaloaei A, et al. in Cell Reports, August 16, 2022
- Evolution of immune genes is associated with the Black Death. Klunk J, et al. in Nature, October 19, 2022
- Neutrophil Recruitment in Pneumococcal Pneumonia. Palmer C & Kimmey J in Frontiers in Cellular and Infection Microbiology, May 13, 2022
- A dissemination-prone morphotype enhances extrapulmonary organ entry by Cryptococcus neoformans. Denham S, et al. in Cell Host & Microbe, September 12, 2022
Recommended Reading - October 16, 2022
- Single-cell analysis identifies the interaction of altered renal tubules with basophils orchestrating kidney fibrosis. Doke T, et al. in Nature Immunology, May 12, 2022
- The metastatic spread of breast cancer accelerates during sleep. Diamantopoulou Z, et al. in Nature, June 22, 2022
- A family of unusual immunoglobulin superfamily genes in an invertebrate histocompatibility complex. Heune A, et al. in PNAS, September 26, 2022
- Innate type 2 immunity controls hair follicle commensalism by Demodex mites. Ricardo-Gonzalez R, et al. in Cell Immunity, August 30, 2022
- Regulation of Klebsiella pneumoniae mucoidy by the bacterial tyrosine kinase Wzc. Khadka S, et al. in bioRxiv, June 5, 2022
Recommended Reading - September 4, 2022
- BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection. Cao Y, et al. in Nature, June 17, 2022
- pH sensing controls tissue inflammation by modulating cellular metabolism and endo-lysosomal function of immune cells. Chen X, et al. in Nature Immunology, June 6, 2022
- Neuropilin-1 is present on Foxp3+ T regulatory cell-derived small extracellular vesicles and mediates immunity against skin transplantation. Campos-Mora M, et al. in Journal of Extracellular Vesicles, June 8, 2022
- Patterns and Predictors of Failure in Recurrent or Refractory Large B-Cell Lymphomas After Chimeric Antigen Receptor T-Cell Therapy. Figura N, et al. in International Journal of Radiation Oncology*Biology*Physics, December 1, 2021
- Global, distinctive, and personal changes in molecular and microbial profiles by specific fibers in humans. Lancaster S, et al. in Cell Host & Microbe, April 27, 2022
Recommended Reading - August 7th, 2022
- Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3. Grebinoski S, et al. in Nature Immunology, May 26, 2022
- Mapping the developing human immune system across organs. Suo C, et al. in Science, June 7, 2022
- Pregnancy enables antibody protection against intracellular infection. Erickson J, et al. in Nature, June 8, 2022
- Intestinal microbiota signatures of clinical response and immune-related adverse events in melanoma patients treated with anti-PD-1. McCulloch J, et al. in Nature Medicine, February 28, 2022
- Tissue remodeling by an opportunistic pathogen triggers allergic inflammation. Agaronyan K, et al. in Immunity, May 10, 2022
Recommended Reading - July 10th, 2022
- Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice. Hunt A, et al. in Science Translational Medicine, April 12, 2022
- Intramuscular AZD7442 (Tixagevimab– Cilgavimab) for Prevention of Covid-19. Levin MJ, et al. in The New England Journal of Medicine, April 20, 2022
- Neoantigen quality predicts immunoediting in survivors of pancreatic cancer. Luksza M, et al. in Nature, May 19, 2022
- Host hepatic metabolism is modulated by gut microbiota-derived sphingolipids. Le HH, et al. in Cell Host & Microbe, June 8, 2022
- Extracellular vesicles from lung tissue drive bone marrow neutrophil recruitment in inflammation. Liu B, et al. in Journal of Extracellular Vesicles, May 20, 2022
Recommended Reading - June 7th, 2022
- Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation. Cautivo K, et al. in Immunity, February 8, 2022
- Immunosuppression broadens evolutionary pathways to drug resistance and treatment failure during Acinetobacter baumannii pneumonia in mice. Huo W, et al. in Nature Microbiology, May 26, 2022
- Depletion of the apical endosome in response to viruses and bacterial toxins provides cell-autonomous host defense at mucosal surfaces. Maeda K, et al. in Cell Host & Microbe, February 9, 2022
- Reversal of the T cell immune system reveals the molecular basis for T cell lineage fate determination in the thymus. Shinzawa M, et al. in Nature Immunology, April 29, 2022
- Human gut bacteria produce ΤΗ17-modulating bile acid metabolites. Paik D, et al. in Nature, March 16, 2022
Recommended Reading - May 8th, 2022
- Structure of a bacterial Rhs effector exported by the type VI secretion system. Gunther P, et al. in PLOS Pathogen, January 5, 2022
- Maternal inflammation is hard for offspring to stomach. Zengeler KE, Lukens JR. in Immunity, January 11, 2022
- The vulnerable versatility of Salmonella antibiotic persisters during infection. Hill P, et al. in Cell Host & Microbe, December 8, 2021
- Diverse events have transferred genes for edible seaweed digestion from marine to human gut bacteria. Pudlo N, et al. in Cell Host & Microbe, March 9, 2022
- Mechanistic insights into consumption of the food additive xanthan gum by the human gut microbiota. Ostrowski M, et al. in Nature Microbiology, April 1, 2022
Recommended Reading - April 10, 2022
- Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement. McCallum M, et al. in Science, January 25, 2022
- TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures. Chaurio R, et al. in Immunity, January 11, 2022
- KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19. Jing L, et al. in Science, March 8, 2022
- Single-cell transcriptional profiling informs efficient reprogramming of human somatic cells to cross-presenting dendritic cells. Fabio R, et al. in Science Immunology, March 4, 2022
- Rare and localized events stabilize microbial community composition and patterns of spatial self-organization in a fluctuating environment. Ciccarese D, et al. in The ISME Journal, January 25, 2022
Recommended Reading - March 6th, 2022
- T cell characteristics associated with toxicity to immune checkpoint blockade in patients with melanoma. Lozano A, et al. in Nature Medicine, January 13, 2022
- Bacterial gasdermins reveal an ancient mechanism of cell death. Johnson A, et al. in Science, January 13, 2022
- Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway. Simpson D, et al. in Immunity, February 8, 2022
- Strain-level fitness in the gut microbiome is an emergent property of glycans and a single metabolite. Park SY, et al. in Cell, January 2, 2022
- A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates. Joyce G, et al. in Science Translational Medicine, December 16, 2021
Recommended Reading - February 6th, 2022
- Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis. Hinrichsen F, et al. in Cell Metabolism, December 7, 2021
- Establishment and characterization of stable, diverse, fecal-derived in vitro microbial communities that model the intestinal microbiota. Aranda-Diaz A, et al. in Cell Host & Microbe, January 19, 2022
- Maternal gut bacteria drive intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4+ T cells. Kim E, et al. in Immunity, January 11, 2022
- An autoimmune stem-like CD8 T cell population drives type 1 diabetes. Gearty S, et al. in Nature, November 30, 2021
- The UGT2A1/UGT2A2 locus is associated with COVID-19-related loss of smell or taste. Shelton J, et al. in Nature Genetics, January 17, 2022
