The fields of infection biology, immunobiology and inflammation research is varied and ever-expanding. Researchers the world over are making discoveries that contribute greatly to our collective understanding of health and disease. VI4 is committed to providing our members, students, and community resources to aid in knowledge-building in these core VI4 research areas. Please check out our current curated recommended reading list below from scientists across the country!
Recommended Reading - February 9th, 2020
- Dietary Intake Regulates the Circulation Inflammatory monocyte Pool. Jordan S, et al. in Cell, August 22, 2019
- Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease. Duan Y, et al. in Nature, November 13, 2019
- Metabolic regulation of gene expression by histone lactylation. Zhang D, et al. in Nature, October 23, 2019
- Cyclophilin A protects HIV-1 from restriction by human TRIM5a. Kim K, et al. in Nature Microbiology, December 4, 2019
- Correlative three-dimensional super-resolution and block-face electron microscopy of whole vitreously frozen cells. Hoffman D, et al. in Science, January 17, 2020
Recommended Reading - November 3rd, 2019
- Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory. Blelloch R, Poggio M, et al. in Cell Reports, April 4, 2019
- Viral complementation of immunodeficiency confers protection against enteric pathogens via interferon-λ. Baldridge MT, Ingle H, et al. in Nature, April 1, 2019
- Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade. Jacquelot N, et al. in Nature, September 3, 2019
- Stochastic Variation in Expression of the Tricarboxylic Acid Cycle Produces Persister Cells. Zalis E, et al. in American Society for Microbiology, September 17, 2019
- The evolution of antibiotic resistance: Clinically relevant evolution studies are needed to help fight the spread of antibiotic resistance. Rekdal V, et al in Science, September 13, 2019
Recommended Reading - October 13th, 2019
- Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial. Voorwerk L, et al in Nature, May 13, 2019
- Human Influenza A Virus Hemagglutinin Glycan Evolution Follows a Temporal Pattern to a Glycan Limit. Yewdell JW, Altman MO, et al in American Society for Microbiology, April 1, 2019
- Microbial Exposure Enhances Immunity to Pathogens Recognized by TLR2 but Increases Susceptibility to Cytokine Storm through TLR4 Sensitization. Huggins M, et al in Cell Reports, August 13, 2019
- Altered immunity of laboratory mice in the natural environment is associated with fungal colonization. Yeung F, et al in bioRxiv, August 21, 2019
- Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism. Rekdal V, et al in Science, June 14, 2019
Recommended Reading - September 11th, 2019
- Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes. Cai Q, Jin H, et al in Science, June 8, 2018
- Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma. Amit I, Li H, et al in Cell Press, February 7, 2019
- Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2. Sonnenberg GF, Zhou L, et al in Nature, April 3, 2019
- A c-di-GMP-Based Switch Controls Local Heterogeneity of Extracellular Matrix Synthesis which Is Crucial for Integrity and Morphogenesis of Escherichia coli Macrocolony Biofilms. Hengge R, Serra D in Journal of Molecular Biology, April 4, 2019
- TCR Transgenic Mice Reveal Stepwise, Multi-site Acquisition of the Distinctive Fat-Treg Phenotype. Li C, Mathis D, et all in Cell Press, June 7, 2018
Recommended Reading - June 7th, 2019
- In Vivo Structures of the Helicobacter pylori cag Type IV Secretion System. Chang YW, Jensen G, et al in Cell Reports, April 17, 2019
- p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells. Ihry R, Kaykas A, et al in Nature Medicine, June 11, 2018
- Vesicle-Cloaked Virus Clusters Are Optimal Units for Inter-organismal Viral Transmission. Santiana M, Altan-Bonnet N, et al in Cell Host & Microbe, August 8, 2018
- Unique Patterns and Biogeochemical Relevance of Two-Component Sensing in Marine Bacteria. Held NA, Saito MA, et al in M Systems - ASM, February 5, 2019
- Neutrophils: New insights and open questions. Ley K, Catz SD, et al in Science Immunology, December 7, 2018
Recommended Reading - October 25th, 2018
-
Discovery and characterization of a prevalent human gut bacterial enzyme sufficient for the inactivation of a family of plant toxins. Koppel N, Balskus EP, et al in eLife, May 15, 2018
-
Staphylococcus aureus clumping factor A is a force-sensitive molecular switch that activates bacterial adhesion. Herman-Bausier P, Dufrêne EF, et al in Proceedings of the National Academy of Sciences, May 2018
-
Blocking Neuronal Signaling to Immune Cells Treats Streptococcal Invasive Infection. Pinho-Ribeiro FA, Chiu IM, et al in Cell, May 10, 2018
-
Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry. Winkels H, Wolf D, et al in Circulation Research, June 8, 2018
-
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. Shalapour S, Karin M, et al in Nature , November 16, 2017
Recommended Reading - September 27th, 2018
-
Identification of a Functionally Unique Family of Penicillin-Binding Proteins. Welsh MA; Taguchi A; et al. in Journal of American Chemical Society, November 28, 2017
-
Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia. Baral P; Umans BD; et al. in Nature Medicine, March 5, 2018
-
Extensive impact of non-antibiotic drugs on human gut bacteria. Maier L; Pruteanu M; et al. in Nature Medicine, March 19, 2018
-
Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients. Gopalakrishnan V; Spencer CN et al. in Science, Jannury 5, 2018
-
Functional interrogation and mining of natively paired human VH:VL antibody repertoires. Wang B; DeKosky BJ et al. in Nature Biotechnology, January 8, 2018
Recommended Reading - August 30th, 2018
- Host Nitric Oxide Disrupts Microbial Cell-to-Cell Communication to Inhibit Staphylococcal Virulence. Urbano R; Fang, FC; et al. in Cell Host Microbe, May 9, 2018
-
Dietary trehalose enhances virulence of epidemic Clostridium difficile. Collins, J; Britton, A; et al in Nature, January 18, 2018
-
Comprehensive skin microbiome analysis reveals the uniqueness of human skin and evidence for phylosymbiosis within the class Mammalia. Ross, AA; Neufeld, JD; et al. in PNAS, June 19, 2018
-
Gut microbiome–mediated bile acid metabolism regulates liver cancer via NKT cells. Ma, C; Gretan, TF; et al. in Science, May 25, 2018
-
In vivo imaging reveals a tumor-associated macrophage–mediated resistance pathway in anti–PD-1 therapy. Arlauckas, S; Pittet, MJ; et al. in Science Translational Medicine May 10, 2017