The fields of infection biology, immunobiology and inflammation research is varied and ever-expanding. Researchers the world over are making discoveries that contribute greatly to our collective understanding of health and disease. VI4 is committed to providing our members, students, and community resources to aid in knowledge-building in these core VI4 research areas. Please check out our current curated recommended reading list below from scientists across the country!
Recommended Reading - March 6th, 2022
- T cell characteristics associated with toxicity to immune checkpoint blockade in patients with melanoma. Lozano A, et al. in Nature Medicine, January 13, 2022
- Bacterial gasdermins reveal an ancient mechanism of cell death. Johnson A, et al. in Science, January 13, 2022
- Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway. Simpson D, et al. in Immunity, February 8, 2022
- Strain-level fitness in the gut microbiome is an emergent property of glycans and a single metabolite. Park SY, et al. in Cell, January 2, 2022
- A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates. Joyce G, et al. in Science Translational Medicine, December 16, 2021
Recommended Reading - January 9th, 2022
- Mapping the cellular origin and early evolution of leukemia in Down syndrome. Wagenblast E, et al. in Science, July 9, 2021
- Arthritis flares mediated by tissue-resident memory T cells in the joint. Chang M, et al. in Cell Reports, October 26, 2021
- An autoimmune stem-like CD8 T cell population drives type 1 diabetes. Gearty S, et al. in Nature, November 30, 2021
- Microbiota-specific T follicular helper cells drive tertiary lymphoid structures and anti-tumor immunity against colorectal cancer. Overacre-Delgoffe A, et al. in Immunity, December 2, 2021
- Heme-Dependent Siderophore Utilization Promotes Iron-Restricted Growth of the Staphylococcus aureus hemB Small-Colony Variant. Batko I, et al. in Journal of Bacteriology, November 19, 2021
Recommended Reading - December 19, 2021
- Hepatic stellate cells suppress NK cell-sustained breast cancer dormancy. Bentires-Alj M et al. in Nature, June 2, 2021
- Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis. Jul`e A, et al. in JCI Insight, September 22, 2021
- The lungfish cocoon is a living tissue with antimicrobial functions. Heimroth R, et al. in Science Advances, November 17, 2021
- Human gut bacterial metabolism drives Th17 activation and colitis. Alexander M, et al. in Cell Host & Microbe, November 24, 2021
- γδ T cell IFNγ production is directly subverted by Yersinia pseudotuberculosis outer protein YopJ in mice and humans. Chu T, et al. in PLOS Pathogens, December 6, 2021
Recommended Reading - October 3, 2021
- MHC class II tetramers engineered for enhanced binding to CD4 improve detection of antigen-specific T cells. Evavold B & Jenkins M et al. in Nature Biotechnology, May 23, 2021
- Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity. Mwakingwe-Omari A, Et al. in Nature, June 30, 2021
- SLFN2 protection of tRNAs from stress-induced cleavage is essential for T cell–mediated immunity. Yue T, et al. in Science, May 14, 2021
- Obligate cross-feeding expands the metabolic niche of bacteria. Oña L. Et al. in Nature Ecology & Evolution, July 15, 2021
- Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis. Koehler H, et al. in Cell Host & Microbe, August 11, 2021
Recommended Reading - August 15, 2021
- SorTn-seq: a high-throughput functional genomics approach to discovering regulators of bacterial gene expression. Fineran P et al. in Nature Protocols, August 4, 2021
- Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity. Duffy P et al. in Nature, June 30, 2021
- An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancer . Thommen D et al. in Nature Medicine, July 8, 2021
- Introducing the Microbes and Social Equity Working Group: Considering the Microbial Components of Social, Environmental, and Health Justice . Morar n et al. in mSystems, July 27, 2021
- Matrix-trapped viruses can prevent invasion of bacterial biofilms by colonizing cells. Nadell C et al. in eLife, July 9, 2021
Recommended Reading - July 18th, 2021
- Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients. Baruch E, et al. in Science, February 5, 2021
- Neurological Manifestations of COVID-19 Feature T Cell Exhaustion and Dedifferentiated Monocytes in Cerebrospinal Fluid. Heming M, et al. in Cell Immunity, January 12, 2021
- Human NLRP1 is a sensor for double-stranded RNA. Bauernfried S, et al. in Science, January 29, 2021
- Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression. DChen S, et al. in Nature Cell Biology, January 8, 2021
- A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression. Ostuni R et al. in Cell Immunity, June 14, 2021
Recommended Reading - December 6th, 2020
- Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes. Friebel, et al. in Cell, June 25, 2020
- A probiotic yeast-based immunotherapy against Clostridioides difficile infection. Chen K, et al. in Science Translational Medicine, October 28, 2020
- Reconstitution and visualization of HIV-1 capsid-dependent replication and integration in vitro. Christensen D, et al. in Science, October 9, 2020
- Fgr Kinase is required for proinflammatory macrophage activation during diet-induced obesity. Acin-Perez R, et al. in Nature Metabolism, September 17, 2020
- Highly multiplexed spatial mapping of microbial communities. Shi H, et al. in Nature, December 2, 2020
Recommended Reading - November 1st, 2020
- Interpersonal Gut Microbiome Variation Drives Susceptibility and Resistance to Cholera Infection. Alavi S, et al. in Cell, June 25, 2020
- Immunogenomic Landscape of Hematological Malignancies. Dufva O, et al. in Cancer Cell, July 9, 2020
- Programmable multistage drug delivery to lymph nodes. Schudel A, et al. in Nature Nanotechnology, June 10, 2020
- Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes. Zakharov P, et al. in Journal of Experimental Medicine, April 6, 2020
- Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans. Mateus J, et al. in Science, October 2, 2020
Recommended Reading - September 6th, 2020
- The stepwise assembly of the neonatal virome is modulated by breastfeeding. Liang G, et al. in Nature, May 15, 2020
- Association between supratentorial pediatric high-grade gliomas involved with the subventricular zone and decreased survival: a multi-institutional retrospective study. Mistry A, et al. in Journal of Nuerosurgery, May 22, 2020
- Cardiovascular effects of glucagon-like peptide 1 receptor agonists: from mechanistic studies in humans to clinical outcomes. Heuvelman V, et al. in Cardiovascular Research, April 1, 2020
- The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides. Wan X, et al. in Nature Immunology, March 9, 2020
- Bacterial polyphosphates interfere with the innate host defense to infection. Roewe J, et al. in Nature Communications, August 12, 2020
Recommended Reading - May 3rd, 2020
- N6-methyladenosine modification enables viral RNA to escape recognition by RNA sensor RIG-I. Lu M, et al. in Nature, April 5, 2020
- Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. Saunders K, et al. in Science, December 6, 2019
- Transcriptomic and epigenetic mechanisms underlying myeloid diversity in the lung. Sajti E, et al. in Nature Immunology, January 20, 2020
- B cells and tertiary lymphoid structures promote immunotherapy response. Helmink B, et al. in Nature, January 15, 2020
- c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies. Bernink J, et al. in Nature Immunology, November 13, 2019
- Structure‐Guided Design of a Group B Streptococcus Type III Synthetic Glycan–Conjugate Vaccine. Oldrini D, et al. in Chemistry Europe, February 14, 2020
- Antirotavirus IgA seroconversion rates in children who receive concomitant oral poliovirus vaccine: A secondary, pooled analysis of Phase II and III trial data from 33 countries. Baker JM, et al. in PLOS Medicine, December 30, 2019
- An anti-inflammatory eicosanoid switch mediates the suppression of type-2 inflammation by helminth larval products. de Los Reyes J M, et al. in Science, April 22, 2020
- Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli. Pleguezuelos-Manzano C, et al. in Nature, February 27, 2020
- Antibiotic Degradation by Commensal Microbes Shields Pathogens. Gjonbalaj M, et al. in American Society for Microbiology Journal, January 14, 2020
