The fields of infection biology, immunobiology and inflammation research is varied and ever-expanding. Researchers the world over are making discoveries that contribute greatly to our collective understanding of health and disease. VI4 is committed to providing our members, students, and community resources to aid in knowledge-building in these core VI4 research areas. Please check out our current curated recommended reading list below from scientists across the country!
Recommended Reading - June 7th, 2020
- Sex-specific adipose tissue imprinting of regulatory T cells. Vasanthakumar A, et al. in Nature, February 26, 2020
- Metabolites released from apoptotic cells act as tissue messengers. Medina C, et al. in Nature, March 18, 2020
- Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation. Zhu J, et al. in Cell Metabolism, November 5, 2019
- Decoy exosomes provide protection against bacterial toxins. Keller M D, et al. in Nature, March 4, 2020
- Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity. McGinty J, et al. in Cell Press, March 17, 2020
- Collective Viral Spread Mediated by Virion Aggregates Promotes the Evolution of Defective Interfering Particles.. Andreu-Moreno, Sanjuan, Rafael in American Society for Microbiology Journal, January 7, 2020
- JC Virus infected choroid plexus epithelial cells produce extracellular vesicles that infect glial cells independently of the virus attachment receptor. O'Hara BA, et al. in PLOS Pathogens, March 4, 2020
- Fecal IgA Levels Are Determined by Strain-Level Differences in Bacteroides Ovatus and Are Modifiable by Gut Microbiota Manipulation. Yang C, et al. in Cell Host & Microbe, February 18, 2020
- Long-term dietary intervention reveals resilience of the gut microbiota despite changes in diet and weight. Fragiadais G, et al. in The American Journal of Clinical Nutrition, March 18, 2020
- Commensal Bacteria Modulate Immunoglobulin A Binding in Response to Host Nutrition. Huus K, et al. in Cell Host & Microbe, April 13, 2020
Recommended Reading - May 3rd, 2020
- N6-methyladenosine modification enables viral RNA to escape recognition by RNA sensor RIG-I. Lu M, et al. in Nature, April 5, 2020
- Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. Saunders K, et al. in Science, December 6, 2019
- Transcriptomic and epigenetic mechanisms underlying myeloid diversity in the lung. Sajti E, et al. in Nature Immunology, January 20, 2020
- B cells and tertiary lymphoid structures promote immunotherapy response. Helmink B, et al. in Nature, January 15, 2020
- c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies. Bernink J, et al. in Nature Immunology, November 13, 2019
- Structure‐Guided Design of a Group B Streptococcus Type III Synthetic Glycan–Conjugate Vaccine. Oldrini D, et al. in Chemistry Europe, February 14, 2020
- Antirotavirus IgA seroconversion rates in children who receive concomitant oral poliovirus vaccine: A secondary, pooled analysis of Phase II and III trial data from 33 countries. Baker JM, et al. in PLOS Medicine, December 30, 2019
- An anti-inflammatory eicosanoid switch mediates the suppression of type-2 inflammation by helminth larval products. de Los Reyes J M, et al. in Science, April 22, 2020
- Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli. Pleguezuelos-Manzano C, et al. in Nature, February 27, 2020
- Antibiotic Degradation by Commensal Microbes Shields Pathogens. Gjonbalaj M, et al. in American Society for Microbiology Journal, January 14, 2020
Recommended Reading - December 8th, 2019
- Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling. Sangjin Kim, et al. in Cell Press, September 19, 2019
- TGFβ blocks IFNα/β release and tumor rejection in spontaneous mammary tumors. Guerin M, et al. in Nature, September 11, 2019
- Large-scale identification of pathogen essential genes during coinfection with sympatric and allopatric microbes. Lewin G, et al. in PNAS, September 24, 2019
- Bulk tissue cell type deconvolution with multi-subject single-cell expression reference. Wang X, et al. in Nature, January 22, 2019
- Migratory DCs activate TGF-β to precondition naïve CD8+ T cells for tissue-resident memory fate. Mani V, et al. in Science, October 11, 2019
Recommended Reading - November 3rd, 2019
- Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory. Blelloch R, Poggio M, et al. in Cell Reports, April 4, 2019
- Viral complementation of immunodeficiency confers protection against enteric pathogens via interferon-λ. Baldridge MT, Ingle H, et al. in Nature, April 1, 2019
- Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade. Jacquelot N, et al. in Nature, September 3, 2019
- Stochastic Variation in Expression of the Tricarboxylic Acid Cycle Produces Persister Cells. Zalis E, et al. in American Society for Microbiology, September 17, 2019
- The evolution of antibiotic resistance: Clinically relevant evolution studies are needed to help fight the spread of antibiotic resistance. Rekdal V, et al in Science, September 13, 2019
Recommended Reading - June 7th, 2019
- In Vivo Structures of the Helicobacter pylori cag Type IV Secretion System. Chang YW, Jensen G, et al in Cell Reports, April 17, 2019
- p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells. Ihry R, Kaykas A, et al in Nature Medicine, June 11, 2018
- Vesicle-Cloaked Virus Clusters Are Optimal Units for Inter-organismal Viral Transmission. Santiana M, Altan-Bonnet N, et al in Cell Host & Microbe, August 8, 2018
- Unique Patterns and Biogeochemical Relevance of Two-Component Sensing in Marine Bacteria. Held NA, Saito MA, et al in M Systems - ASM, February 5, 2019
- Neutrophils: New insights and open questions. Ley K, Catz SD, et al in Science Immunology, December 7, 2018
Recommended Reading - May 10th, 2019
- Translocation of a gut pathobiont drives autoimmunity in mice and humans. Vieira SM, Goodman AL, Kriegel MA, et al in Science, March 9, 2018
- Structure of the peptidoglycan polymerase RodA resolved by evolutionary coupling analysis. Sjodt M, Rudner DZ, Kruse AC, et al in Nature, April 5, 2018
- Spatial determinants of quorum signaling in a Pseudomonas aeruginosa infection model. Darch S, Shear JB, Whiteley M, et al in PNAS, April 17, 2018
- Bacterial sensors define intracellular free energies for correct enzyme metalation. Osman D, Chivers PT, Robinson NJ, et al in Nature: Chemical Biology, January 28, 2019
- Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers. Gruosso T, Haibe-Kains B, Park M, et al in The Journal of Clinical Investigation, February 12, 2019
Recommended Reading - March 18th, 2019
- Systematic discovery of antiphage defense systems in the microbial pangenome. Doron S, Sorek R, et al in Science, March 2, 2018
- Pulmonary neuroendocrine cells amplify allergic asthma responses. Sui P, Sun X, et al in Science, June 8, 2018
- Peptidoglycan synthesis drives an FtsZ-treadmilling-independent step of cytokinesis. Monteiro JM, Pinho MG, et al in Nature, February 22, 2018
- Immune cell census in murine atherosclerosis: cytometry by time of flight illuminates vascular myeloid cell diversity. Cole JE, Monaco C, et al in Cardiovascular Research, August 1, 2018
- A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein. Tan J, Lanzavecchia, et al in Nature Medicine, March 19, 2018
Recommended Reading - February 22nd, 2019
- The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet. Olson C, Hsiao EY, et al in Cell, June 14, 2018
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Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity. Kornberg MD, Snyder SH, et al in Science, April 27, 2018
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Single-cell bioluminescence imaging of deep tissue in freely moving animals. Iwano S, Miyawaki A, et al in Science, February 23, 2018
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Identification of Near-Pan-neutralizing Antibodies against HIV-1 by Deconvolution of Plasma Humoral Responses. Sajadi MM, DeVico AL, et al in Cell, June 14, 2018
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Septal secretion of protein A in Staphylococcus aureus requires SecA and lipoteichoic acid synthesis. Yu W, Schneewind O, et al in eLIFE, May 14, 2018
Recommended Reading - January 25th, 2019
- Disruption of staphylococcal aggregation protects against lethal lung injury. Hook J, Bhattacharya J, et al in The Journal of Clinical Investigation, February 12, 2018
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Heme ameliorates dextran sodium sulfate-induced colitis through providing intestinal macrophages with noninflammatory profiles. Kayama H, Takeda K, et al in PNAS, August 14, 2018
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Precision editing of the gut microbiota ameliorates colitis. Zhu W, Winter SE, et al in Nature, January 11, 2018
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Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism. Trompette A, Marsland BJ, et al in Cell Immunity, May 15, 2018
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Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination. Burnett D, Goodnow CC, et al in Science, April 13, 2018
Recommended Reading - January 7th, 2019
- Salt-responsive gut commensal modulates Th17 axis and disease. Wilck N, Müller DN, et al in Nature, November 15, 2017
- Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors. Routy B, Zitvogel L, et al in Science, November 2, 2017
- Redox-Sensing Under Hypochlorite Stress and Infection Conditions by the Rrf2-Family Repressor HypR in Staphylococcus aureus. Van Loi V, Antelmann H, et al in Antioxidants & Redox Signaling, September 1, 2018
- Dietary and Microbial Oxazoles Induce Intestinal Inflammation by Modulating Aryl Hydrocarbon Receptor Responses. Iyer s, Blumberg RS, et al in Cell, May 17, 2018
- Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis. Cochain C, Zernecke A, et al in Circulation Research, June 8, 2018
