The fields of infection biology, immunobiology and inflammation research is varied and ever-expanding. Researchers the world over are making discoveries that contribute greatly to our collective understanding of health and disease. VI4 is committed to providing our members, students, and community resources to aid in knowledge-building in these core VI4 research areas. Please check out our current curated recommended reading list below from scientists across the country!
Recommended Reading - March 6th, 2022
VI4 Curation Team
- T cell characteristics associated with toxicity to immune checkpoint blockade in patients with melanoma. Lozano A, et al. in Nature Medicine, January 13, 2022
- Bacterial gasdermins reveal an ancient mechanism of cell death. Johnson A, et al. in Science, January 13, 2022
- Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway. Simpson D, et al. in Immunity, February 8, 2022
- Strain-level fitness in the gut microbiome is an emergent property of glycans and a single metabolite. Park SY, et al. in Cell, January 2, 2022
- A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates. Joyce G, et al. in Science Translational Medicine, December 16, 2021
Recommended Reading - December 19, 2021
VI4 Curation Team
- Hepatic stellate cells suppress NK cell-sustained breast cancer dormancy. Bentires-Alj M et al. in Nature, June 2, 2021
- Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis. Jul`e A, et al. in JCI Insight, September 22, 2021
- The lungfish cocoon is a living tissue with antimicrobial functions. Heimroth R, et al. in Science Advances, November 17, 2021
- Human gut bacterial metabolism drives Th17 activation and colitis. Alexander M, et al. in Cell Host & Microbe, November 24, 2021
- γδ T cell IFNγ production is directly subverted by Yersinia pseudotuberculosis outer protein YopJ in mice and humans. Chu T, et al. in PLOS Pathogens, December 6, 2021
Recommended Reading - October 3, 2021
VI4 Curation Team
- MHC class II tetramers engineered for enhanced binding to CD4 improve detection of antigen-specific T cells. Evavold B & Jenkins M et al. in Nature Biotechnology, May 23, 2021
- Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity. Mwakingwe-Omari A, Et al. in Nature, June 30, 2021
- SLFN2 protection of tRNAs from stress-induced cleavage is essential for T cell–mediated immunity. Yue T, et al. in Science, May 14, 2021
- Obligate cross-feeding expands the metabolic niche of bacteria. Oña L. Et al. in Nature Ecology & Evolution, July 15, 2021
- Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis. Koehler H, et al. in Cell Host & Microbe, August 11, 2021
Recommended Reading - August 15, 2021
VI4 Curation Team
- SorTn-seq: a high-throughput functional genomics approach to discovering regulators of bacterial gene expression. Fineran P et al. in Nature Protocols, August 4, 2021
- Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity. Duffy P et al. in Nature, June 30, 2021
- An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancer . Thommen D et al. in Nature Medicine, July 8, 2021
- Introducing the Microbes and Social Equity Working Group: Considering the Microbial Components of Social, Environmental, and Health Justice . Morar n et al. in mSystems, July 27, 2021
- Matrix-trapped viruses can prevent invasion of bacterial biofilms by colonizing cells. Nadell C et al. in eLife, July 9, 2021