Spotlight

VI4 Spotlight

VI4 Spotlight is where you can find the latest news and happenings at the Vanderbilt Institute for Infection, Immunology, and Inflammation. 

Spotlight: Julie Bastarache, MD & Brandon Baer, PhD

Dr. Bastarache is a physician-scientist with a mechanistic and translational research program in acute and chronic lung diseases including acute respiratory distress syndrome (ARDS) and bronchiectasis. She also has an interest in non-pulmonary organ dysfunction during sepsis and studies delirium and acute kidney injury in experimental models. Her diverse research approach uses a combination of cell, mouse and human models of lung injury and repair to define the fundamental cellular and molecular mechanisms that regulate organ injury including ARDS, delirium and acute kidney injury as well large clinical and genetic datasets to generate insights into individual variability in risk and outcomes from ARDS. She also has an interest in leveraging the EMR and novel phenotyping methods to identify and study subjects with underlying genetic causes of chronic lung diseases such as bronchiectasis with the goal of developing tools to help clinicians achieve a timely and accurate diagnosis. Brandon Baer, PhD, is Postdoctoral Research Fellow in the Division of Allergy, Pulmonary and Critical Care Medicine at Vanderbilt University Medical Center. He is responsible for designing and executing research initiatives to assess novel therapeutics for respiratory disease. Over his career, he has initiated and led strategic approaches with both academic and biotech partners to enhance the efficacy as well as delivery of intrapulmonary therapeutics (mainly for the treatment of inflammation and infection). Passionate about improving the current treatment paradigms for respiratory disease, he thrives in collaborative environments that empower diverse teams of inter-disciplinary scientists to tackle scientific challenges.

Spotlight: Jennifer Shuman, Ph.D.

Jennifer Shuman, Ph.D. is a postdoctoral fellow in the Tim Cover lab in the department of Medicine and department of Pathology, Microbiology and Immunology. Jennifer received her B.S. in Genetics and in Microbiology from Clemson University in May 2018, where she worked with Dr. Ingram-Smith on Entamoeba histolytica metabolism. She graduated from the Interdisciplinary Graduate Program at Vanderbilt in the Spring of 2024 and is currently a postdoc in Dr. Tim Cover's lab. Her research interests include how Helicobacter pylori adapts to mixed infections and different environmental conditions. Outside of the lab, Jennifer likes to read, eat, and explore Nashville with her family.

Spotlight: Caitlin Murdoch, Ph.D.

Caitlin Murdoch Ph.D. is a postdoctoral fellow in the Eric Skaar lab in the department of Pathology, Microbiology and Immunology. Caitlin grew up on Merritt Island, a barrier island on Florida’s Space Coast. After receiving her B.S. in Microbiology from the University of Florida, she moved to Durham, NC to pursue graduate studies at Duke University. There, she earned her PhD in Molecular Genetics and Microbiology in the lab of Dr. John Rawls. For her dissertation, she used zebrafish to study mechanisms by which the microbiota shape the development of the innate immune system. In the Skaar lab, Caitlin continues to use gnotobiotic zebrafish as a model to investigate the impact of metals on shaping inter-bacterial interactions in the intestine.....Click the image on the left to continue reading.

Spotlight: Jane Ferguson, Ph.D.

Jane Ferguson Ph.D. is an Associate Professor of Medicine in the Division of Cardiovascular Medicine and an Associate Director of the Vanderbilt Microbiome Innovation Center. Dr. Ferguson completed a BA in Human Genetics at Trinity College Dublin, and a PhD in Nutrigenomics at University College Dublin, Ireland, before moving to Philadelphia for postdoctoral training in Cardiovascular Genomics at the University of Pennsylvania. Dr. Ferguson moved to Nashville to join the faculty at Vanderbilt in October 2014.....Click the image on the left to continue reading.

Spotlight: Annet Kirabo, DVM, MSc, PhD and Ashley L. Pitzer, PhD

Annet Kirabo, DVM, MSc, PhD, is an Associate Professor of Medicine in the Division of Clinical Pharmacology within the Department of Medicine at Vanderbilt University Medical Center. Dr. Kirabo is interested in understanding the role of inflammation in hypertension. She obtained her PhD from the Department of Physiology and Functional Genomics at the University of Florida College of Medicine. During her PhD training, she was awarded an American Heart Association (AHA) predoctoral fellowship to determine the specific involvement of vascular smooth muscle cell expression of Jak2 in the pathogenesis of cardiovascular disease. Ashley L. Pitzer, PhD, is a Research Instructor in the Division of Clinical Pharmacology within the Department of Medicine at Vanderbilt University Medical Center. She is interested in the molecular mechanisms and genes responsible for cardiac hypertrophy, fibrosis, and hypertension. As a PhD candidate in the Department of Pharmacology and Toxicology at the Virginia Commonwealth School of Medicine, her doctoral dissertation was a molecular study of the mechanism of RIG-I inflammasome in vascular endothelial cell dysfunction....click the image to the left to continue reading!

Spotlight: Tegy J. Vadakkan, Ph.D.

Dr. Tegy Vadakkan received his PhD from the University of Houston, Texas and completed postdoctoral training at Baylor College of Medicine. Before coming to Vanderbilt in January of 2022, Tegy was a lead research technologist at the Boston Children's Hospital at Harvard Medical School... Click the image on the left to continue reading.

Trainee Spotlight: Brad Reinfeld & Matt Madden

Brad Reinfeld, Ph.D. is a part of the Vanderbilt Medical Scientist Training Program. He was a member of the Kim Rathmell lab and recently defended his dissertation, "Deciphering Cell Specific Metabolic Programs in the Tumor Microenvironment." He is now finishing his medical training at the Vanderbilt School of Medicine. Matt Madden, Ph.D. is a also part of the Vanderbilt Medical Scientist Training Program. He was a member of the Jeff Rathmell lab and recently defended his dissertation, "Glucose and Glutamine in the Tumor Microenvironment and CD8 T Cell Function." He is now finishing his medical training at the Vanderbilt School of Medicine.....Click the image on the left to continue reading.

Trainee Spotlight: Kelsey Pilewski & Andrea Shiakolas

Kelsey Pilewski, Ph.D. and Andrea Shiakolas, Ph.D. are part of the Ivelin Georgiev Lab at Vanderbilt Vaccine Center. Originally from upstate New York, Kelsey received her undergraduate degrees in Biochemistry and French from the University at Buffalo in 2016. Kelsey joined the Georgiev Lab in 2017 to complete her thesis research investigating the discovery and characterization of antibody and vaccine candidates against a number of pathogens. She received her PhD from Vanderbilt University in March 2022 and joined the lab as a postdoctoral fellow shortly after, where she is now working to expand the discovery capabilities of LIBRA-seq. Outside of lab, Kelsey can be found hiking or baking. Andrea Shiakolas is a postdoctoral fellow in the Georgiev laboratory. She completed her PhD at Vanderbilt in the Georgiev laboratory in 2022. Her research focuses on developing and applying antibody discovery technologies (LIBRA-seq) against a variety of viral pathogens, including HIV, influenza, and SARS-CoV-2. She is originally from Dallas, Texas and obtained her undergraduate degree from Vanderbilt in 2015. She also worked at the Vaccine Research Center in Dr. John Mascola’s group at the NIH studying the antibody/virus co-evolution in the context of HIV. Outside of the lab, she loves playing with her puppy Doug, drinking wine, and going hiking... Click the image on the left to continue reading.

Postdoc Spotlight: Seth Zost, Ph.D.

Seth graduated from the University of Pennsylvania in 2013 with a B.A. in Biochemistry and History and a M.S. in Chemistry. Following graduation, Seth joined the lab of Dr. Scott Hensley at the University of Pennsylvania and studied human antibody responses to influenza A viruses and the viral evasion of pre-existing immunity. Seth defended his PhD in 2018. In the lab, Seth is continuing to study antibody responses against respiratory viruses with special interests in defining conserved sites on viral proteins that are targeted by human antibodies and identifying how prior exposure shapes human antibody responses against viruses like influenza and SARS-CoV-2....Click the image on the left to continue reading.

Faculty Spotlight: Jane F. Ferguson, Ph.D.

Dr. Ferguson completed a BA in Human Genetics at Trinity College Dublin, and a PhD in Nutrigenomics at University College Dublin, Ireland, before moving to Philadelphia for postdoctoral training in Cardiovascular Genomics at the University of Pennsylvania. She moved to Nashville to join the faculty at Vanderbilt in October 2014... Click Dr. Ferguson's photo to continue reading.