Jing Wang wins 2024 Faculty Development Award
Congratulations to research assistant professor Jing Wang, the 2024 winner of our department's Faculty Development Award. Her proposal was deemed the best in a field of highly competitive submissions for a one-year pilot grant. Dr. Wang will use this funding to support an investigation that she hopes to build into a larger project: “Taking advantage of the dramatically increasing number of single-cell transcriptomics and epigenomics studies, the project aims to develop cell-type-specific enhancer-mediated regulatory maps for functionally interpreting and prioritizing enhancer risk variants and causal genes.” Dr. Wang is shown here describing her project at the August 2024 faculty meeting, when the award was announced. Her accomplishments include first-authorship of a 2023 paper in Cancers (Basel) on small RNA profiling in human extracellular vesicles,
First-authored paper in JAMIA by Andrew Guide
Congratulations to senior biostatistician Andrew Guide on first-authorship of "Balancing efficacy and computational burden: weighted mean, multiple imputation, and inverse probability weighting methods for item non-response in reliable scales," an article published in JAMIA: A Scholarly Journal of Informatics in Health and Biomedicine on August 13. Co-authors include assistant in biostatistics Shawn Garbett, senior biostatistician Xiaoke (Sarah) Feng, and professor Qingxia (Cindy) Chen, who is the paper's corresponding author, with colleagues in VICTR, DBMI, and Ohio State's Department of Internal Medicine. The study examined ways of interpreting non-responses to the Physical Activity Neighborhood Environment Scale (PANES) in the All of Us Social Determinants of Health survey and to what degree computationally intensive approaches are advisable. In the words of Guide and his co-authors, their goal is "to inform researchers on considerations for handling incomplete data in participant surveys, utilize the data received as efficiently and accurately as possible, and better understand how to use surveys with missingness to conduct accurate research." Guide, Garbett, Chen, and some other team members published another paper on interpreting All of Us data earlier this year; Guide, Garbett, and Feng also served as teaching asistants in this year's Summer Institute short course on the All of Us research program.
Figure 1 in Guide et al., "Balancing efficacy..." For the full caption, view the figure at its journal page or within the full paper.
First-authored paper in Nature Communications by Jia Li
Congratulations to postdoctoral fellow Jia Li, professor and chair Yu Shyr, and professor Qi Liu on the August 22 publication of Identification and multimodal characterization of a specialized epithelial cell type associated with Crohn’s disease (CD) in Nature Communications. Dr. Li is first author of the paper and Dr. Liu its corresponding author. The team's study of terminal ileum and ascending colon (LND) cells in CD patients has led to findings that "suggest a potential pathogenic role" for such cells in inflammatory bowel disease (IBD).
Figure 1 from the paper. Visit it at the publication site for the full caption.
Scholars from National Cheng Kung University join our department
We are delighted to welcome two Taiwanese scholars to our department as visiting researchers: student Jo-Ying Hung and professor Kuo-Jung Lee, both based at National Cheng Kung University (NCKU), a public research institution in Tainan.
Jo-Ying Hung is a PhD candidate in statistics at NCKU, where she previously earned her BBA and MS degrees. She is formally a visiting student observer who is working with professor Yu Shyr from August 1, 2024, through February 28, 2025, to explore meta-regression techniques for analyzing estimated odds rations and hazard ratios in clinical research and learn about developing, using, and improving advanced statistical methods, tools, and repositories for biomedical research with attention to RNA sequencing, omics, and other key areas of investigation. She has co-authored peer-reviewed papers published in Cardiovascular Diabetology, American Journal of Occupational Therapy, World Neurosurgery, and Scientific Reports, and won an Outstanding Doctoral Student Scholarship at NCKU.
Kuo-Jung Lee is director of the Institutional Research Division at NCKU, as well as a professor in its Department of Statistics and Institute of Data Science. His sabbatical in Nashville is made possible in part by a Senior Fulbright Research Grant. He earned his PhD in statistics at the University of Minnesota, won NCKU's Excellent Teacher Award in 2020, and was most recently first author of papers appearing in Statistics in Medicine and Nanomaterials (Basel). During his visiting scholar appointment, which runs through July 31, 2025, Dr. Lee will work on "Bayesian Feature Selection and Spatio-Temporal Joint Modeling to the Integration of Radiomics and Multiplatform Genomic Data."
$3.4 million research grant targets risk of heart attack, stroke
Professor Jonathan Schildcrout and associate professor Ran Tao are on this team, along with the analysts and app developers in our department who work closely with BioVU.
Margaret Cullum promoted to program manager
We are pleased to announce the promotion of Margaret Cullum to program manager, in effect as of August 1. A graduate of the University of North Carolina, with a bachelor's degree in journalism and internships at POPSUGAR and Giadzy, Cullum joined the department in 2023 and has provided crucial administrative support for special events (including ICSA 2024 and our 20th anniversary festivities), seminars and short courses (including the CQS Summer Institutes, last October's ASA traveling course, MSCI 5044, and other offerings), the summer internship program for underrepresented undergraduates, the Bellevue Community Food Bank drive, and more. She's also heavily involved with website and bulletin board maintenance, social media updates, and other promotional endeavors, including the coordination of department-branded clothing and swag.
Epigenetic change to DNA associated with cancer risk in "multi-omics" study
This study was co-authored by professor Fei Ye.
Mario Davidson named director-elect of VUMC's Academy for Excellence in Education
In addition to raising the bar of medical and statistics education at VUMC and beyond, Dr. Davidson is actively engaged with the professional development of researchers. He recently taught “DEPICT: A Franmework for Ethical Reasoning for Statistics and Data Science” at the 2024 Joint Statistical Meetings; he’s led seminars on effective posters and other aspects of communication for a variety of groups at VUMC, including the Clinical Research Center (CRC) Research Skills Workshop, Edge for Scholars, and the Vanderbilt Biostatistics Summer Internships for Underrepresented Undergraduates; and, he is first author of a study published in Academic Medicine earlier this year, with a video abstract that can be viewed at https://vimeo.com/948731583.
First-authored paper in JAMIA by Siwei Zhang
Congratulations to PhD candidate Siwei Zhang, alumnus Nicholas Strayer (PhD 2020; now at Posit), senior biostatistician Yajing Li, and assistant professor Yaomin Xu on the publication of “PheMIME: an interactive web app and knowledge base for phenome-wide, multi-institutional multimorbidity analysis” in the Journal of the American Medical Informatics Association on August 10.