Software

TrioDenovo: A Bayesian framework for de novo mutation calling in parents-offspring trios.

More info is available: http://genome.sph.umich.edu/wiki/Triodenovo

 

PolyMutt: A likelihood framework for calling genotypes and de novo mutations in general pedigrees.

More info is available: http://genome.sph.umich.edu/wiki/Polymutt

 

PolyMutt2: A tools to leverage identity-by-descent (IBD) allele sharing for genotype calling in general pedigrees.

More info is available: http://genome.sph.umich.edu/wiki/Polymutt2

 

TrioCaller: A linkage-disequilibrium framework to genotype inference in parents-offspring trios.

More info is available: http://genome.sph.umich.edu/wiki/TrioCaller

 

gTDT: A group-wise TDT for haplotype-based association testing of rare variants with complex disease.

More info is available: http://genome.sph.umich.edu/wiki/GTDT

 

iDriver: A software suite to perform integrative modelling of multi-oimcs data to identify cancer driver genes.

More info is availalbe: http://genome.sph.umich.edu/wiki/Idriver

 

dVAR: A framework for de novo pattern discovery in high-dimensional genomics data for accurate assessment of the functionality of noncoding variants. More info is availalbe: https://www.vumc.org/cgg/dvar