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Kahn E, D'Haese PF, Dawant B, Allen L, Kao C, Charles PD, Konrad P. Deep brain stimulation in early stage Parkinson's disease: operative experience from a prospective randomised clinical trial. Journal of neurology, neurosurgery, and psychiatry. 2012 Feb;83(83). 164-70. NIHMSID: NIHMS477546.
Abstract
Recent evidence suggests that deep brain stimulation of the subthalamic nucleus (STN-DBS) may have a disease modifying effect in early Parkinson's disease (PD). A randomised, prospective study is underway to determine whether STN-DBS in early PD is safe and tolerable.