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The Computational Neurogenomics Team (CNT) is a part of the Vanderbilt Memory & Alzheimer's Center and led by Dr. Timothy J. Hohman. Dr. Hohman's programmatic research focuses on understanding how certain individuals accumulate Alzheimer's disease neuropathology without showing clinical symptoms of the disease. He has identified molecular drivers of such resilience through genomic and proteomic analyses leveraging neuroimaging and neuropathology endophenotypes. 

The team seeks to integrate these diverse data types into a precision medicine approach, focusing on characterizing the best predictors of risk and resilience given an individual's age, sex, genetic, and neuropathological context. Through transdisciplinary collaboration, we seek to facilitate a more rapid move from genomic discovery to therapeutic development.