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Wu Y, Libby JB, Dumitrescu LC, De Jager PL, Menon V, Schneider JA, Bennett DA, Hohman TJ. Association of ten VEGF family genes with Alzheimer's disease endophenotypes at single cell resolution. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024 Dec 6.
Abstract
Using a single-nucleus transcriptome derived from the dorsolateral prefrontal cortex of 424 Religious Orders Study and the Rush Memory and Aging Project (ROS/MAP) participants, we investigated the cell type-specific effect of ten vascular endothelial growth factor (VEGF) genes on Alzheimer's disease (AD) endophenotypes.