Disentangling the genetic underpinnings of neuropsychiatric symptoms in Alzheimer's disease in the Alzheimer's Disease Sequencing Project: Study design and methodology.

Ray NR, Kumar A, Zaman A, Del Rosario P, Mena PR, Manoochehri M, Stein C, De Vito AN, Sweet RA, Hohman TJ, Cuccaro ML, Beecham GW, Huey ED, Reitz C. Disentangling the genetic underpinnings of neuropsychiatric symptoms in Alzheimer's disease in the Alzheimer's Disease Sequencing Project: Study design and methodology. Alzheimer's & dementia (Amsterdam, Netherlands). 16(16). e70000. PMID: 39183746 [PubMed] PMCID: PMC11342352

Neuropsychiatric symptoms (NPS) are highly prevalent in Alzheimer's disease (AD). There are no effective treatments targeting these symptoms.