Male sex and obesity are associated with residual plasma HIV-1 viremia in persons on long-term antiretroviral therapy.

Cyktor JC, Bosch RJ, Mar H, Macatangay BJ, Collier AC, Hogg E, Godfrey C, Eron JJ, McMahon DK, Mellors JW, Gandhi RT. Male sex and obesity are associated with residual plasma HIV-1 viremia in persons on long-term antiretroviral therapy. The Journal of infectious diseases. 2020 Jun 30. PMID: 32603416 [PubMed]

Abstract

Although adipose tissue has been proposed to harbor part of the HIV-1 reservoir, the influence of host characteristics, including sex and body-mass index (BMI), on measures of HIV-1 persistence during ART are incompletely understood.