2015
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Rojas JM, Bruinstroop E, Printz RL, Alijagic-Boers A, Foppen E, Turney MK, George L, Beck-Sickinger AG, Kalsbeek A, Niswender KD. Central nervous system neuropeptide Y regulates mediators of hepatic phospholipid remodeling and very low-density lipoprotein triglyceride secretion via sympathetic innervation. Molecular metabolism. 2015 Mar;4(4). 210-21.
2014
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Morris LC, Nance KD, Gentry PR, Days EL, Weaver CD, Niswender CM, Thompson AD, Jones CK, Locuson CW, Morrison RD, Daniels JS, Niswender KD, Lindsley CW. Discovery of (S)-2-cyclopentyl-N-((1-isopropylpyrrolidin2-yl)-9-methyl-1-oxo-2,9-dihydro-1H-pyrrido[3,4-b]indole-4-carboxamide (VU0453379): a novel, CNS penetrant glucagon-like peptide 1 receptor (GLP-1R) positive allosteric modulator (PAM). Journal of medicinal chemistry. 2014 Dec 11;57(57). 10192-7.
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Chen Z, Guo L, Zhang Y, Walzem RL, Pendergast JS, Printz RL, Morris LC, Matafonova E, Stien X, Kang L, Coulon D, McGuinness OP, Niswender KD, Davies SS. Incorporation of therapeutically modified bacteria into gut microbiota inhibits obesity. The Journal of clinical investigation. 2014 Aug;124(124). 3391-406.
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Saunders C, Siuta M, Robertson SD, Davis AR, Sauer J, Matthies HJ, Gresch PJ, Airey DC, Lindsley CW, Schetz JA, Niswender KD, Veenstra-Vanderweele JM, Galli A. Neuronal ablation of p-Akt at Ser473 leads to altered 5-HT1A/2A receptor function. Neurochemistry international. 2014 Jul;73(73). 113-21. NIHMSID: NIHMS530172.
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Kocalis HE, Hagan SL, George L, Turney MK, Siuta MA, Laryea GN, Morris LC, Muglia LJ, Printz RL, Stanwood GD, Niswender KD. Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis. Molecular metabolism. 2014 Jul;3(3). 394-407.
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Silver HJ, Kang H, Keil CD, Muldowney JA, Kocalis H, Fazio S, Vaughan DE, Niswender KD. Consuming a balanced high fat diet for 16 weeks improves body composition, inflammation and vascular function parameters in obese premenopausal women. Metabolism: clinical and experimental. 2014 Apr;63(63). 562-73. NIHMSID: NIHMS599372.
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Morris LC, Days EL, Turney M, Mi D, Lindsley CW, Weaver CD, Niswender KD. A Duplexed High-Throughput Screen to Identify Allosteric Modulators of the Glucagon-Like Peptide 1 and Glucagon Receptors. Journal of biomolecular screening. 2014 Feb 13;19(19). 847-858. NIHMSID: NIHMS580600.
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Pendergast JS, Branecky KL, Huang R, Niswender KD, Yamazaki S. Wheel-running activity modulates circadian organization and the daily rhythm of eating behavior. Frontiers in psychology. 5(5). 177 p.
2013
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Pendergast JS, Niswender KD, Yamazaki S. The complex relationship between the light-entrainable and methamphetamine-sensitive circadian oscillators: evidence from behavioral studies of Period-mutant mice. The European journal of neuroscience. 2013 Jul 22. NIHMSID: NIHMS509624.
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Silver HJ, Niswender KD, Kullberg J, Berglund J, Johansson L, Bruvold M, Avison MJ, Welch EB. Comparison of gross body fat-water magnetic resonance imaging at 3 Tesla to dual-energy X-ray absorptiometry in obese women. Obesity (Silver Spring, Md.). 2013 Apr;21(21). 765-74. NIHMSID: NIHMS383731.
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Pendergast JS, Branecky KL, Yang W, Ellacott KL, Niswender KD, Yamazaki S. High-fat diet acutely affects circadian organisation and eating behavior. The European journal of neuroscience. 2013 Apr;37(37). 1350-6. NIHMSID: NIHMS461151.
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West J, Niswender KD, Johnson JA, Pugh ME, Gleaves L, Fessel JP, Hemnes AR. A potential role for insulin resistance in experimental pulmonary hypertension. The European respiratory journal. 2013 Apr;41(41). 861-71. NIHMSID: NIHMS497316.
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Alcendor DJ, Block FE, Cliffel DE, Daniels JS, Ellacott KL, Goodwin CR, Hofmeister LH, Li D, Markov DA, May JC, McCawley LJ, McLaughlin B, McLean JA, Niswender KD, Pensabene V, Seale KT, Sherrod SD, Sung HJ, Tabb DL, Webb DJ, Wikswo JP. Neurovascular unit on a chip: implications for translational applications. Stem cell research & therapy. 4 Suppl 1(4 Suppl 1). S18.
2012
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Rojas JM, Stafford JM, Saadat S, Printz RL, Beck-Sickinger AG, Niswender KD. Central nervous system neuropeptide Y signaling via the Y1 receptor partially dissociates feeding behavior from lipoprotein metabolism in lean rats. American journal of physiology. Endocrinology and metabolism. 2012 Dec 15;303(303). E1479-88.
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Pendergast JS, Oda GA, Niswender KD, Yamazaki S. Period determination in the food-entrainable and methamphetamine-sensitive circadian oscillator(s). Proceedings of the National Academy of Sciences of the United States of America. 2012 Aug 28;109(109). 14218-23.
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Kocalis HE, Turney MK, Printz RL, Laryea GN, Muglia LJ, Davies SS, Stanwood GD, McGuinness OP, Niswender KD. Neuron-specific deletion of peroxisome proliferator-activated receptor delta (PPARδ) in mice leads to increased susceptibility to diet-induced obesity. PloS one. 7(7). e42981.
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Silver HJ, Niswender KD, Keil CD, Jiang L, Feng Q, Chiu S, Krauss RM, Wilke RA. CNR1 genotype influences HDL-cholesterol response to change in dietary fat intake. PloS one. 7(7). e36166.
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Pendergast JS, Niswender KD, Yamazaki S. Tissue-specific function of Period3 in circadian rhythmicity. PloS one. 7(7). e30254.
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Hagan S, Niswender KD. Neuroendocrine regulation of food intake. Pediatric blood & cancer. 2012 Jan;58(58). 149-53.
2011
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Mazei-Robison MS, Koo JW, Friedman AK, Lansink CS, Robison AJ, Vinish M, Krishnan V, Kim S, Siuta MA, Galli A, Niswender KD, Appasani R, Horvath MC, Neve RL, Worley PF, Snyder SH, Hurd YL, Cheer JF, Han MH, Russo SJ, Nestler EJ. Role for mTOR signaling and neuronal activity in morphine-induced adaptations in ventral tegmental area dopamine neurons. Neuron. 2011 Dec 22;72(72). 977-90. NIHMSID: NIHMS333904.
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Daws LC, Avison MJ, Robertson SD, Niswender KD, Galli A, Saunders C. Insulin signaling and addiction. Neuropharmacology. 2011 Dec;61(61). 1123-8. NIHMSID: NIHMS286938.
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Niswender KD. Basal insulin: beyond glycemia. Postgraduate medicine. 2011 Jul;123(123). 27-37.
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Niswender KD. Basal insulin: physiology, pharmacology, and clinical implications. Postgraduate medicine. 2011 Jul;123(123). 17-26.
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Silver HJ, Dietrich MS, Niswender KD. Effects of grapefruit, grapefruit juice and water preloads on energy balance, weight loss, body composition, and cardiometabolic risk in free-living obese adults. Nutrition & metabolism. 8(8). 8 p.
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Niswender KD, Daws LC, Avison MJ, Galli A. Insulin regulation of monoamine signaling: pathway to obesity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2011 Jan;36(36). 359-60.
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Speed N, Saunders C, Davis AR, Owens WA, Matthies HJ, Saadat S, Kennedy JP, Vaughan RA, Neve RL, Lindsley CW, Russo SJ, Daws LC, Niswender KD, Galli A. Impaired striatal Akt signaling disrupts dopamine homeostasis and increases feeding. PloS one. 6(6). e25169.
2010
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Siuta MA, Robertson SD, Kocalis H, Saunders C, Gresch PJ, Khatri V, Shiota C, Kennedy JP, Lindsley CW, Daws LC, Polley DB, Veenstra-Vanderweele J, Stanwood GD, Magnuson MA, Niswender KD, Galli A. Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice. PLoS biology. 8(8). e1000393.
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Silver HJ, Welch EB, Avison MJ, Niswender KD. Imaging body composition in obesity and weight loss: challenges and opportunities. Diabetes, metabolic syndrome and obesity : targets and therapy. 3(3). 337-47.
2009
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Robinson JR, Niswender KD. What are the risks and the benefits of current and emerging weight-loss medications? Current diabetes reports. 2009 Oct;9(9). 368-75.
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Posey KA, Clegg DJ, Printz RL, Byun J, Morton GJ, Vivekanandan-Giri A, Pennathur S, Baskin DG, Heinecke JW, Woods SC, Schwartz MW, Niswender KD. Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet. American journal of physiology. Endocrinology and metabolism. 2009 May;296(296). E1003-12.
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Sarruf DA, Yu F, Nguyen HT, Williams DL, Printz RL, Niswender KD, Schwartz MW. Expression of peroxisome proliferator-activated receptor-gamma in key neuronal subsets regulating glucose metabolism and energy homeostasis. Endocrinology. 2009 Feb;150(150). 707-12.
2008
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Huizinga MM, Niswender KD, Gebretsadik T, Rothman RL, Shintani AK, Elasy TA. Insulin use and weight maintenance in well-controlled type 2 diabetes: a prospective cohort study. Obesity (Silver Spring, Md.). 2008 Aug;16(16). 1933-7. NIHMSID: NIHMS112674.
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Niswender KD, Beech BM. Obesity: increasing awareness of novel environmental factors. Diabetes. 2008 Jul;57(57). 1786-7.
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Stafford JM, Yu F, Printz R, Hasty AH, Swift LL, Niswender KD. Central nervous system neuropeptide Y signaling modulates VLDL triglyceride secretion. Diabetes. 2008 Jun;57(57). 1482-90. NIHMSID: NIHMS528498.
2007
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Niswender KD, Magnuson MA. Obesity and the beta cell: lessons from leptin. The Journal of clinical investigation. 2007 Oct;117(117). 2753-6.
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Saraswathi V, Gao L, Morrow JD, Chait A, Niswender KD, Hasty AH. Fish oil increases cholesterol storage in white adipose tissue with concomitant decreases in inflammation, hepatic steatosis, and atherosclerosis in mice. The Journal of nutrition. 2007 Jul;137(137). 1776-82.
2006
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Gelling RW, Morton GJ, Morrison CD, Niswender KD, Myers MG, Rhodes CJ, Schwartz MW. Insulin action in the brain contributes to glucose lowering during insulin treatment of diabetes. Cell metabolism. 2006 Jan;3(3). 67-73.
2005
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Morton GJ, Gelling RW, Niswender KD, Morrison CD, Rhodes CJ, Schwartz MW. Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons. Cell metabolism. 2005 Dec;2(2). 411-20.
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Morrison CD, Morton GJ, Niswender KD, Gelling RW, Schwartz MW. Leptin inhibits hypothalamic Npy and Agrp gene expression via a mechanism that requires phosphatidylinositol 3-OH-kinase signaling. American journal of physiology. Endocrinology and metabolism. 2005 Dec;289(289). E1051-7.
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Morton GJ, Blevins JE, Williams DL, Niswender KD, Gelling RW, Rhodes CJ, Baskin DG, Schwartz MW. Leptin action in the forebrain regulates the hindbrain response to satiety signals. The Journal of clinical investigation. 2005 Mar;115(115). 703-10.
2004
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Schwartz MW, Niswender KD. Adiposity signaling and biological defense against weight gain: absence of protection or central hormone resistance? The Journal of clinical endocrinology and metabolism. 2004 Dec;89(89). 5889-97.
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Niswender KD, Baskin DG, Schwartz MW. Insulin and its evolving partnership with leptin in the hypothalamic control of energy homeostasis. Trends in endocrinology and metabolism: TEM. 2004 Oct;15(15). 362-9.
2003
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Morton GJ, Niswender KD, Rhodes CJ, Myers MG, Blevins JE, Baskin DG, Schwartz MW. Arcuate nucleus-specific leptin receptor gene therapy attenuates the obesity phenotype of Koletsky (fa(k)/fa(k)) rats. Endocrinology. 2003 May;144(144). 2016-24.
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Niswender KD, Gallis B, Blevins JE, Corson MA, Schwartz MW, Baskin DG. Immunocytochemical detection of phosphatidylinositol 3-kinase activation by insulin and leptin. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2003 Mar;51(51). 275-83.
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Niswender KD, Morrison CD, Clegg DJ, Olson R, Baskin DG, Myers MG, Seeley RJ, Schwartz MW. Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia. Diabetes. 2003 Feb;52(52). 227-31.
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Niswender KD, Schwartz MW. Insulin and leptin revisited: adiposity signals with overlapping physiological and intracellular signaling capabilities. Frontiers in neuroendocrinology. 2003 Jan;24(24). 1-10.