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Arimura K, Kammer M, Rahman SMJ, Sheau-Chiann C, Zhao S, Heidi C, Eisenberg R, Zou Y, Antic S, Richmond B, Tagaya E, Grogan E, Massion P, Maldonado F. Elucidating the role of EPPK1 in lung adenocarcinoma development. BMC cancer. 2024 Apr 10;24(24). 441 p.
Abstract
We recently found that epiplakin 1 (EPPK1) alterations were present in 12% of lung adenocarcinoma (LUAD) cases and were associated with a poor prognosis in early-stage LUAD when combined with other molecular alterations. This study aimed to identify a probable crucial role for EPPK1 in cancer development.