Prescription Opioid Dose After Vaginal Delivery and the Risk of Serious Opioid-Related Events: A Retrospective Cohort Study.

Wiese AD, Osmundson SS, Mitchel E, Adgent M, Phillips S, Patrick SW, Horn A, Samuels LR, Griffin MR, Grijalva CG. Prescription Opioid Dose After Vaginal Delivery and the Risk of Serious Opioid-Related Events: A Retrospective Cohort Study. Women's health issues : official publication of the Jacobs Institute of Women's Health. 31(31). 376-383. PMID: 33865673 [PubMed] PMCID: PMC8260443 NIHMSID: NIHMS1696550.

Abstract

Postpartum opioid use remains common among women with uncomplicated vaginal delivery and may increase the risk of serious opioid-related events. Therefore, we examined the association between the dose of the first filled opioid prescription after vaginal delivery and the subsequent risk of serious opioid-related events.