Performance of Phenotype Algorithms for the Identification of Opioid-Exposed Infants.

Wiese AD, Phillippi JC, Muhar A, Polic A, Liu G, Loch SF, Ong HH, Su WC, Leech AA, Reese T, Wei WQ, Patrick SW. Performance of Phenotype Algorithms for the Identification of Opioid-Exposed Infants. Hospital pediatrics. 2024 Jun 1;14(14). 438-447. PMID: 38804051 [PubMed] PMCID: PMC11137624

Abstract

Observational studies examining outcomes among opioid-exposed infants are limited by phenotype algorithms that may under identify opioid-exposed infants without neonatal opioid withdrawal syndrome (NOWS). We developed and validated the performance of different phenotype algorithms to identify opioid-exposed infants using electronic health record data.