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Wylie SA, Van den Wildenberg W, Ridderinkhof KR, Claassen DO, Wooten GF, Manning CA. Differential susceptibility to motor impulsivity among functional subtypes of Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry. 2012 Dec;83(83). 1149-54. NIHMSID: NIHMS482348.
Abstract
Parkinson's disease patients with predominant postural instability and gait difficulties (PIGD) may experience unique cognitive difficulties compared to patients with tremor predominant (TD) symptoms. PIGD patients are also at high risk for falling, and some of the worst fallers seem to react impulsively to their environment. We tested the hypothesis that PIGD patients show poorer control over motor impulses compared to TD patients.