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Rivera ES, Weiss A, Migas LG, Freiberg JA, Djambazova KV, Neumann EK, Van de Plas R, Spraggins JM, Skaar EP, Caprioli RM. Imaging mass spectrometry reveals complex lipid distributions across biofilm layers. Journal of mass spectrometry and advances in the clinical lab. 2022 Nov;26(26). 36-46.
Abstract
Although is the leading cause of biofilm-related infections, the lipidomic distributions within these biofilms is poorly understood. Here, lipidomic mapping of biofilm cross-sections was performed to investigate heterogeneity between horizontal biofilm layers.