Does Intrawound Vancomycin Application During Spine Surgery Create Vancomycin-Resistant Organism?

Chotai S, Wright PW, Hale AT, Jones WA, McGirt MJ, Patt JC, Devin CJ. Does Intrawound Vancomycin Application During Spine Surgery Create Vancomycin-Resistant Organism? Neurosurgery. 2017 May 1;80(80). 746-753. PMID: 28387851 [PubMed]

Abstract

Surgical site infection (SSI) following spine surgery is a morbid and expensive complication. The use of intrawound vancomycin is emerging as a solution to reduce SSI. The development of vancomycin-resistant pathogens is an understandable concern.