Funding Opportunities

Current funding opportunities related to TB and HIV, expired RFAs will be hidden after closing date. Sort using the tags menu to the right.

 

For funding opportunities related to global health, please see the Vanderbilt Institute for Global Health announcements found here.

Halting Tuberculosis (TB) Transmission (R01 Clinical Trial Optional), Expires: December 05, 2024

Open Date (Earliest Submission Date): November 04, 2024

Expiration Date: December 05, 2024


Funds Available and Anticipated Number of Awards
NIAID intends to commit $6,000,000 in FY 2025 to fund 4-5 awards.

Award Budget
Application budgets are not expected to exceed $750,000 in direct costs per year, and should reflect the actual needs of the project. 

Award Project Period
The scope of the proposed project should determine the project period. The maximum project period is 5 years.

Find additional information here
 

TB Elimination Alliance Announces 2023 Mini-Grant Program Awardees

The Tuberculosis Elimination Alliance (TEA), led by the Association of Asian Pacific Community Health Organizations (AAPCHO), Asian & Pacific Islander American Health Forum (APIAHF), Hepatitis B Foundation (HBF), and Stop TB USA, with the support of the Centers for Disease Control and Prevention’s (CDC) Division of TB Elimination, announced that it awarded a total of $250,000 to 12 community health organizations serving Asian, Asian American (A/AA), Native Hawaiian, and Pacific Islander (NH/PI), Hispanic/Latino and African American communities that are disproportionately impacted by tuberculosis (TB).

 

TEA offered a third cycle of 12 mini-grant awards totaling $250,000 to community providers that increase awareness and build capacity on TB testing and treatment. The newly awarded mini-grant recipients in this cycle are as follows:

  • Arkansas Coalition of Marshallese (Springdale, AR)
  • Asian Pacific Health Foundation (San Diego, CA)
  • EthnoMed (Seattle, WA)
  • Jericho Road Community Health Center (Buffalo, NY)
  • Midwest Asian Health Association (Chicago, IL)
  • Mission Neighborhood Health Center (San Francisco, CA)
  • Regional Pacific Islander Taskforce (San Francisco, CA)
  • Revive Community Health (Tempe, AZ)
  • Rural Women's Health Project (Gainesville, FL)
  • San Diego County Medical Society Foundation, dba Champions for Health (San Diego, CA)
  • Todu Guam Foundation, Ltd. (Tamuning, Guam)
  • We Are TB / Somos TB (National)

Since its inception in 2019, TEA has distributed over $800,000 in mini-grant funding to 36 organizations. TEA, our members, partners, and mini-grantees look forward to building on the progress that we have made so far towards TB elimination. 

For more information on TEA, please visit www.tbeliminationalliance.org.

Analyzing Early Events in TB and TB/HIV Infection for Interventional Targets (R01 - Clinical Trial Not Allowed) expires 10/12/2023

Due Dates: October 11, 2023

Open Date: Earliest Submission Date: September 11, 2023

The purpose of this Notice of Funding Opportunity (NOFO) is to support mechanistic studies of the early stage of Mycobacterium tuberculosis (Mtb) infection, with and without HIV, to identify interventional targets for vaccine and host-directed therapies. This Notice of Funding Opportunity (NOFO) will support mechanistic studies of early Mtb infection (defined as the time between Mtb exposure and early-stage granuloma formation) in the airway and lung with the ultimate goal of understanding these events in the setting of HIV co-infection.   

More information here

Peer Reviewed Medical Research Program (PRMRP)

The Peer Reviewed Medical Research Program (PRMRP), established in fiscal year 1999 (FY99), has supported research across the full range of science and medicine, with an underlying goal of enhancing the health, care, and well-being of military Service Members, Veterans, retirees, and their family members.

FY2023 Funding Mechanisms have been announced! The Congressionally Directed Topic Areas include:

  • Clinical Trial Award (CTA)
  • Discovery Award (DA)
  • Focused Program Award (FPA)
  • Investigator-Initiated Research Award (IIRA)
  • Lifestyle and Behavioral Health Interventions Research Award (LBIRA)
  • Technology/Therapeutic Development Award (TTDA)

Letter of Intent is Due: April 19th, 2023

Full Applications are Due: May 31st, 2023

Learn more about this opportunity at https://cdmrp.health.mil/funding/prmrp

 

Notice of Special Interest (NOSI): Halting Tuberculosis (TB) Transmission

Open Date (Earliest Submission Date): February 05, 2023

Expiration Date: January 08, 2026

The purpose of this Notice of Special Interest (NOSI) is to highlight NIAID’s interest in accepting applications that aim to understand the critical drivers of Tuberculosis (TB) transmission at the individual and population levels in high-burden settings. Applicants are encouraged to develop effective methods to measure rates of TB transmission that rely on an increased understanding of the biomedical basis of transmission and related risk factors and to develop and assess potential interventions, including low-cost and low-tech options, to prevent TB transmission.

For more information click here

Sustained Release of Antivirals for Treatment or Prevention of HIV or Treatment of Latent TB/HBV (SRATP), due September 07, 2022

Open Date (Earliest Submission Date): September 07, 2022

Expiration Date: May 08, 2025

The purpose of this Notice is to encourage new applications to support further development of a diverse and comprehensive portfolio of SR/LA products for prevention and treatment of HIV. SR/LA antiretroviral products will have a minimum window of protection of three (3) months from either a single dosing (injection, oral administration) or continuous dosing regimen (implant, transdermal patch, etc.) to reflect current state of SR/LA drug market for HIV treatment or prevention.

This Notice also encourages applications to develop once-a-month SR/LA strategies for treatment of latent TB and hepatitis B

https://grants.nih.gov/grants/guide/notice-files/NOT-AI-22-042.html?utm…

Biomarker Signatures of TB Infection in Young Children With and Without HIV (R01 Clinical Trial Not Allowed), due 06/08/2022

Open Date (Earliest Submission Date): May 08, 2022

Expiration Date: June 09, 2022

The purpose of this Funding Opportunity Announcement (FOA) is to advance research to discover and validate novel biomarkers of Tuberculosis (TB) infection and subsequent risk of progression to TB disease in young children with and without HIV.

https://grants.nih.gov/grants/guide/rfa-files/RFA-AI-22-015.html

Improved Drug Susceptibility Testing (DST) for Tuberculosis (R01 Clinical Trial Not Allowed), due 07/08/2022

Open Date (Earliest Submission Date): June 08, 2022

Expiration Date: July 09, 2022

The purpose of this Funding Opportunity Announcement (FOA) is to support the development of new diagnostic technologies for tuberculosis (TB) drug susceptibility testing (DST), including point of care (POC) DST and companion diagnostics for new TB drugs.

https://grants.nih.gov/grants/guide/rfa-files/RFA-AI-22-016.html

NIAID Funding Opportunity: Brazil Regional Prospective Observational Research in Tuberculosis

Brazil Regional Prospective Observational Research in Tuberculosis (RePORT) (U01 Clinical Trial Not Allowed)

Application open date: November 08, 2021

Expiration Date: December 09, 2021

The purpose of this Funding Opportunity Announcement (FOA) is to support a Brazil-US Regional Prospective Observational Research in Tuberculosis (RePORT) network to advance TB and TB/HIV science. The RePORT Brazil network will leverage and build upon Brazilian cohorts currently following adult and pediatric populations with active TB disease and their contacts or other high TB-risk individuals to address key research questions of regional and global interest. Specific areas supported under this program include, but are not limited to, research and development projects in TB/HIV in the areas of molecular epidemiology, diagnostics, biomarkers, vaccine development, and the impact of co-morbidities such as HIV and diabetes. Research outcomes should be capable of advancing tools with public health impact or of influencing decision making in TB public health to inform stakeholders on the best practices for early prevention, diagnosis, and clinical management of TB and TB/HIV.

Click here for more information about this funding opportunity!

 

Advancing Vaccine Adjuvant Research for Tuberculosis (TB)

Solicitation for BAA-DAIT-75N93021R00008 entitled, "Advancing Vaccine Adjuvant Research for Tuberculosis (TB)"

Contract Opportunity Type: Solicitation
 

The goal of this program is to further the development of TB vaccines through sideby-side comparisons of adjuvants in combination with TB immunogens, and to establish immunological profiles of adjuvants that work through different mechanisms, facilitating the identification of the most promising adjuvant:Mtb immunogen candidates for clinical development and potential immune correlates of protection. The range of adjuvants to be evaluated may include novel classes of adjuvants being developed for other infections and immune-oncology therapeutics, as well as adjuvants already being developed for TB vaccines. It is anticipated that one cost reimbursement, completion type contract will be awarded for a five [5]-year period of performance beginning on or about 7/22/22.
NIAID anticipates that the average annual total cost (direct and indirect costs combined) is $4 million per contract. However, it is anticipated that the total cost for the award(s) may vary depending upon the scope of the project and the technical objectives of the award(s). The length of time for which funding is requested should be consistent with the nature and complexity of the proposed research. In no event shall the period of performance proposed by an offeror exceed five [5] years. Any responsible offeror may submit a proposal which shall be considered by the Agency. This BAA will be available electronically on/about April, 28, 2021, and may be accessed through here. This notice does not commit the Government to award a contract. No collect calls will be accepted. No facsimile transmissions will be accepted.

Published: Apr 28, 2021 12:41 pm EDT
Offers Due: Aug 10, 2021 03:00 pm EDT