Vanderbilt Epidemiology Center's Annual Top Ten Publications

VEC members publish annually over 300 scientific articles in research journals. At the end of each calendar year, VEC faculty vote to select the publications they consider the most important publications that were led by VEC members for the year. These votes are compiled into the Top Ten publications list.

Top Ten 2022

Holowatyj AN, Wen W, Gibbs T, Seagle HM, Keller SR, Edwards DRV, Washington MK, Eng C, Perea J, Zheng W, Guo X. Racial/Ethnic and Sex Differences in Somatic Cancer Gene Mutations among Patients with Early-Onset Colorectal Cancer. Cancer Discov. 2023 Mar 1;13(3):570-579. doi: 10.1158/2159-8290.CD-22-0764. PMID: 36520636

Ely EW, Ramanan AV, Kartman CE, de Bono S, Liao R, Piruzeli MLB, Goldman JD, Saraiva JFK, Chakladar S, Marconi VC; COV-BARRIER Study Group. Efficacy and safety of baricitinib plus standard of care for the treatment of critically ill hospitalised adults with COVID-19 on invasive mechanical ventilation or extracorporeal membrane oxygenation: an exploratory, randomised, placebo-controlled trial. Lancet Respir Med. 2022 Apr;10(4):327-336. doi: 10.1016/S2213-2600(22)00006-6. Epub 2022 Feb 3. Erratum in: Lancet Respir Med. 2022 Feb 11;: PMID: 35123660.

Holowatyj AN, Washington MK, Tavtigian SV, Eng C, Horton C. Inherited Cancer Susceptibility Gene Sequence Variations Among Patients With Appendix Cancer. JAMA Oncol. 2022 Nov 11;9(1):95–101. doi: 10.1001/jamaoncol.2022.5425. Epub ahead of print. PMID: 36368039.

He J, Wen W, Beeghly A, Chen Z, Cao C, Shu XO, Zheng W, Long Q, Guo X. Integrating transcription factor occupancy with transcriptome-wide association analysis identifies susceptibility genes in human cancers. Nat Commun. 2022 Nov 19;13(1):7118. doi: 10.1038/s41467-022-34888-0. PMID: 36402776.

Munro HM, Shrubsole MJ, Zheng W, Wen W, Blot WJ. Smoking Quit Rates Among Menthol vs Nonmenthol Smokers: Implications Regarding a US Ban on the Sale of Menthol Cigarettes. J Natl Cancer Inst. 2022 Jul 11;114(7):953-958. doi: 10.1093/jnci/djac070. PMID: 35445262.

Breeyear JH, Keaton JM, Torstenson ES, Smith AH, Klarin D, Damrauer SM, Natarajan P, Van Driest SL, Weiner JG, Kannankeril PJ, Edwards TL. Diastolic Blood Pressure Alleles Improve Congenital Heart Defect Repair Outcomes. Circ Res. 2022 Apr;130(7):1030-1037. doi: 10.1161/CIRCRESAHA.121.319842. Epub 2022 Feb 24. PMID: 35199555.

Akwo E, Pike MM, Ertuglu LA, Vartanian N, Farber-Eger E, Lipworth L, Perwad F, Siew E, Hung A, Bansal N, de Boer I, Kestenbaum B, Cox NJ, Ikizler TA, Wells Q, Robinson-Cohen C. Association of Genetically Predicted Fibroblast Growth Factor-23 with Heart Failure: A Mendelian Randomization Study. Clin J Am Soc Nephrol. 2022 Aug;17(8):1183-1193. doi: 10.2215/CJN.00960122. Epub 2022 Jul 28. PMID: 35902130.

Castilho JL, Bian A, Jenkins CA, Shepherd BE, Sigel K, Gill MJ, Kitahata MM, Silverberg MJ, Mayor AM, Coburn SB, Wiley D, Achenbach CJ, Marconi VC, Bosch RJ, Horberg MA, Rabkin CS, Napravnik S, Novak RM, Mathews WC, Thorne JE, Sun J, Althoff KN, Moore RD, Sterling TR, Sudenga SL; North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) of the International Epidemiology Databases to Evaluate AIDS (IeDEA). CD4/CD8 Ratio and Cancer Risk Among Adults With HIV. J Natl Cancer Inst. 2022 Jun 13;114(6):854-862. doi: 10.1093/jnci/djac053. PMID: 35292820.

Yang Y, Tao R, Shu X, Cai Q, Wen W, Gu K, Gao YT, Zheng Y, Kweon SS, Shin MH, Choi JY, Lee ES, Kong SY, Park B, Park MH, Jia G, Li B, Kang D, Shu XO, Long J, Zheng W. Incorporating Polygenic Risk Scores and Nongenetic Risk Factors for Breast Cancer Risk Prediction Among Asian Women. JAMA Netw Open. 2022 Mar 1;5(3):e2149030. doi: 10.1001/jamanetworkopen.2021.49030. PMID: 35311964.

Yang JJ, Keohane LM, Pan XF, Qu R, Shu XO, Lipworth L, Braun K, Steinwandel MD, Dai Q, Shrubsole M, Zheng W, Blot WJ, Yu D. Association of Healthy Lifestyles With Risk of Alzheimer Disease and Related Dementias in Low-Income Black and White Americans. Neurology. 2022 Aug 30;99(9):e944-e953. doi: 10.1212/WNL.0000000000200774. Epub 2022 Jun 13. PMID: 35697505.

Top Ten 2021

Ray WA, Chung CP, Stein CM, Smalley W, Zimmerman E, Dupont WD, Hung AM, Daugherty JR, Dickson A, Murray KT. Association of Rivaroxaban vs Apixaban With Major Ischemic or Hemorrhagic Events in Patients With Atrial Fibrillation. JAMA. 2021 Dec 21;326(23):2395-2404. doi: 10.1001/jama.2021.21222. PMID: 34932078; PMCID: PMC8693217.

Wang F, Zheng W, Bailey CE, Mayer IA, Pietenpol JA, Shu XO. Racial/Ethnic Disparities in All-Cause Mortality among Patients Diagnosed with Triple-Negative Breast Cancer. Cancer Res. 2021 Feb 15;81(4):1163-1170. doi: 10.1158/0008-5472.CAN-20-3094. Epub 2020 Dec 3. PMID: 33272926.

Wen W, Chen Z, Bao J, Long Q, Shu XO, Zheng W, Guo X. Genetic variations of DNA bindings of FOXA1 and co-factors in breast cancer susceptibility. Nat Commun. 2021 Sep 13;12(1):5318. doi: 10.1038/s41467-021-25670-9. PMID: 34518541; PMCID: PMC8438084.

Marconi VC, Ramanan AV, de Bono S, Kartman CE, Krishnan V, Liao R, Piruzeli MLB, Goldman JD, Alatorre-Alexander J, de Cassia Pellegrini R, Estrada V, Som M, Cardoso A, Chakladar S, Crowe B, Reis P, Zhang X, Adams DH, Ely EW; COV-BARRIER Study Group. Efficacy and safety of baricitinib for the treatment of hospitalised adults with COVID-19 (COV-BARRIER): a randomised, double-blind, parallel-group, placebo-controlled phase 3 trial. Lancet Respir Med. 2021 Dec;9(12):1407-1418. doi: 10.1016/S2213-2600(21)00331-3. Epub 2021 Sep 1. Erratum in: Lancet Respir Med. 2021 Oct;9(10):e102. PMID: 34480861; PMCID: PMC8409066.

Ray WA, Chung CP, Murray KT, Malow BA, Daugherty JR, Stein CM. Mortality and concurrent use of opioids and hypnotics in older patients: A retrospective cohort study. PLoS Med. 2021 Jul 15;18(7):e1003709. doi: 10.1371/journal.pmed.1003709. PMID: 34264928; PMCID: PMC8321368.

Rebeiro PF, Aronoff DM, Smith MK. The Impact of State Mask-Wearing Requirements on the Growth of Coronavirus Disease 2019 Cases, Hospitalizations, and Deaths in the United States. Clin Infect Dis. 2021 Nov 2;73(9):1703-1706. doi: 10.1093/cid/ciab101. PMID: 33550400; PMCID: PMC7929015.

Giulino-Roth L, Pei Q, Buxton A, Bush R, Wu Y, Wolden SL, Constine LS, Kelly KM, Schwartz CL, Friedman DL. Subsequent malignant neoplasms among children with Hodgkin lymphoma: a report from the Children's Oncology Group. Blood. 2021 Mar 18;137(11):1449-1456. doi: 10.1182/blood.2020007225. PMID: 33512412; PMCID: PMC7976513.

Sundermann AC, Velez Edwards DR, Slaughter JC, Wu P, Jones SH, Torstenson ES, Hartmann KE. Week-by-week alcohol consumption in early pregnancy and spontaneous abortion risk: a prospective cohort study. Am J Obstet Gynecol. 2021 Jan;224(1):97.e1-97.e16. doi: 10.1016/j.ajog.2020.07.012. Epub 2020 Jul 13. PMID: 32673615; PMCID: PMC7807528.

Turi KN, McKennan C, Gebretsadik T, Snyder B, Seroogy CM, Lemanske RF Jr, Zoratti E, Havstad S, Ober C, Lynch S, McCauley K, Yu C, Jackson DJ, Gern JE, Hartert TV; ECHO-CREW investigators. Unconjugated bilirubin is associated with protection from early-life wheeze and childhood asthma. J Allergy Clin Immunol. 2021 Jul;148(1):128-138. doi: 10.1016/j.jaci.2020.12.639. Epub 2021 Jan 10. PMID: 33434532; PMCID: PMC8271087.

Chen B, Scurrah CR, McKinley ET, Simmons AJ, Ramirez-Solano MA, Zhu X, Markham NO, Heiser CN, Vega PN, Rolong A, Kim H, Sheng Q, Drewes JL, Zhou Y, Southard-Smith AN, Xu Y, Ro J, Jones AL, Revetta F, Berry LD, Niitsu H, Islam M, Pelka K, Hofree M, Chen JH, Sarkizova S, Ng K, Giannakis M, Boland GM, Aguirre AJ, Anderson AC, Rozenblatt-Rosen O, Regev A, Hacohen N, Kawasaki K, Sato T, Goettel JA, Grady WM, Zheng W, Washington MK, Cai Q, Sears CL, Goldenring JR, Franklin JL, Su T, Huh WJ, Vandekar S, Roland JT, Liu Q, Coffey RJ, Shrubsole MJ, Lau KS. Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps. Cell. 2021 Dec 22;184(26):6262-6280.e26. doi: 10.1016/j.cell.2021.11.031. Epub 2021 Dec 14. PMID: 34910928; PMCID: PMC8941949.

Top Ten 2020

Grijalva CG, Rolfes MA, Zhu Y, McLean HQ, Hanson KE, Belongia EA, Halasa NB, Kim A, Reed C, Fry AM, Talbot HK. Transmission of SARS-COV-2 Infections in Households - Tennessee and Wisconsin, April-September 2020. MMWR Morb Mortal Wkly Rep. 2020 Nov 6;69(44):1631-1634. doi: 10.15585/mmwr.mm6944e1. PMID: 33151916; PMCID: PMC7643897. 

Wang F, Zheng W, Bailey CE, Mayer IA, Pietenpol JA, Shu XO. Racial/Ethnic Disparities in All-Cause Mortality among Patients Diagnosed with Triple-Negative Breast Cancer. Cancer Res. 2021 Feb 15;81(4):1163-1170. doi: 10.1158/0008-5472.CAN-20-3094. Epub 2020 Dec 3. PMID: 33272926. 

Rebeiro PF, Jenkins CA, Bian A, Lake JE, Bourgi K, Moore RD, Horberg MA, Matthews WC, Silverberg MJ, Thorne J, Mayor AM, Lima VD, Palella FJ, Saag MS, Althoff KN, Gill MJ, Wong C, Klein MB, Crane HM, Marconi VC, Shepherd BE, Sterling TR, Koethe JR. Risk of Incident Diabetes Mellitus, Weight Gain, and their Relationships with Integrase Inhibitor-based Initial Antiretroviral Therapy Among Persons with HIV in the US and Canada. Clin Infect Dis. 2020 Sep 16:ciaa1403. doi: 10.1093/cid/ciaa1403. Epub ahead of print. PMID: 32936919. 

Beeghly-Fadiel A, Khankari NK, Delahanty RJ, Shu XO, Lu Y, Schmidt MK, Bolla MK, Michailidou K, Wang Q, Dennis J, Yannoukakos D, Dunning AM, Pharoah PDP, Chenevix-Trench G, Milne RL, Hunter DJ, Per H, Kraft P, Simard J, Easton DF, Zheng W. A Mendelian randomization analysis of circulating lipid traits and breast cancer risk. Int J Epidemiol. 2020 Aug 1;49(4):1117-1131. doi: 10.1093/ije/dyz242. PMID: 31872213; PMCID: PMC7750975. 

Guo X, Lin W, Wen W, Huyghe J, Bien S, Cai Q, Harrison T, Chen Z, Qu C, Bao J, Long J, Yuan Y, Wang F, Bai M, Abecasis GR, Albanes D, Berndt SI, Bézieau S, Bishop DT, Brenner H, Buch S, Burnett-Hartman A, Campbell PT, Castellví-Bel S, Chan AT, Chang-Claude J, Chanock SJ, Cho SH, Conti DV, Chapelle A, Feskens EJM, Gallinger SJ, Giles GG, Goodman PJ, Gsur A, Guinter M, Gunter MJ, Hampe J, Hampel H, Hayes RB, Hoffmeister M, Kampman E, Kang HM, Keku TO, Kim HR, Le Marchand L, Lee SC, Li CI, Li L, Lindblom A, Lindor N, Milne RL, Moreno V, Murphy N, Newcomb PA, Nickerson DA, Offit K, Pearlman R, Pharoah PDP, Platz EA, Potter JD, Rennert G, Sakoda LC, Schafmayer C, Schmit SL, Schoen RE, Schumacher FR, Slattery ML, Su YR, Tangen CM, Ulrich CM, van Duijnhoven FJB, Van Guelpen B, Visvanathan K, Vodicka P, Vodickova L, Vymetalkova V, Wang X, White E, Wolk A, Woods MO, Casey G, Hsu L, Jenkins MA, Gruber SB, Peters U, Zheng W. Identifying Novel Susceptibility Genes for Colorectal Cancer Risk From a Transcriptome-Wide Association Study of 125,478 Subjects. Gastroenterology. 2021 Mar;160(4):1164-1178.e6. doi: 10.1053/j.gastro.2020.08.062. Epub 2020 Oct 12. PMID: 33058866; PMCID: PMC7956223. 

Shu X, Long J, Cai Q, Kweon SS, Choi JY, Kubo M, Park SK, Bolla MK, Dennis J, Wang Q, Yang Y, Shi J, Guo X, Li B, Tao R, Aronson KJ, Chan KYK, Chan TL, Gao YT, Hartman M, Kee Ho W, Ito H, Iwasaki M, Iwata H, John EM, Kasuga Y, Soon Khoo U, Kim MK, Kong SY, Kurian AW, Kwong A, Lee ES, Li J, Lophatananon A, Low SK, Mariapun S, Matsuda K, Matsuo K, Muir K, Noh DY, Park B, Park MH, Shen CY, Shin MH, Spinelli JJ, Takahashi A, Tseng C, Tsugane S, Wu AH, Xiang YB, Yamaji T, Zheng Y, Milne RL, Dunning AM, Pharoah PDP, García-Closas M, Teo SH, Shu XO, Kang D, Easton DF, Simard J, Zheng W. Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants. Nat Commun. 2020 Mar 5;11(1):1217. doi: 10.1038/s41467-020-15046-w. PMID: 32139696; PMCID: PMC7057957. 

Wiese AD, Everson J, Grijalva CG. Social distancing measures: evidence of interruption of seasonal influenza activity and early lessons of the SARS-CoV-2 pandemic. Clin Infect Dis. 2020 Jun 20:ciaa834. doi: 10.1093/cid/ciaa834. Epub ahead of print. PMID: 32562538; PMCID: PMC7337694. 

Holowatyj AN, Washington MK, Salaria SN, Lieu CH, Idrees K, Chandler PD, Hampel H, Martin RL, Lewis MA, Eng C. Early-Onset Appendiceal Cancer Survival by Race or Ethnicity in the United States. Gastroenterology. 2020 Oct;159(4):1605-1608. doi10.1053/j.gastro.2020.06.011. Epub 2020 Jun 13. PMID: 32540351. 

Nguyen S, Li H, Yu D, Gao J, Gao Y, Tran H, Xiang YB, Zheng W, Shu XO. Adherence to dietary recommendations and colorectal cancer risk: results from two prospective cohort studies. Int J Epidemiol. 2020 Feb 1;49(1):270-280. doi: 10.1093/ije/dyz118. PMID: 31203367; PMCID: PMC7124505. 

Yang JJ, Lipworth LP, Shu XO, Blot WJ, Xiang YB, Steinwandel MD, Li H, Gao YT, Zheng W, Yu D. Associations of choline-related nutrients with cardiometabolic and all-cause mortality: results from 3 prospective cohort studies of blacks, whites, and Chinese. Am J Clin Nutr. 2020 Mar 1;111(3):644-656. doi: 10.1093/ajcn/nqz318. PMID: 31915809; PMCID: PMC7049525.
 

 

Top Ten: 2019

Giri A, Hellwege JN, Keaton JM, Park J, Qiu C, Warren HR, Torstenson ES, Kovesdy CP, Sun YV, Wilson OD, Robinson-Cohen C, Roumie CL, Chung CP, Birdwell KA, Damrauer SM, DuVall SL, Klarin D, Cho K, Wang Y, Evangelou E, Cabrera CP, Wain LV, Shrestha R, Mautz BS, Akwo EA, Sargurupremraj M, Debette S, Boehnke M, Scott LJ, Luan J, Zhao JH, Willems SM, Thériault S, Shah N, Oldmeadow C, Almgren P, Li-Gao R, Verweij N, Boutin TS, Mangino M, Ntalla I, Feofanova E, Surendran P, Cook JP, Karthikeyan S, Lahrouchi N, Liu C, Sepúlveda N, Richardson TG, Kraja A, Amouyel P, Farrall M, Poulter NR; Understanding Society Scientific Group; International Consortium for Blood Pressure; Blood Pressure-International Consortium of Exome Chip Studies, Laakso M, Zeggini E, Sever P, Scott RA, Langenberg C, Wareham NJ, Conen D, Palmer CNA, Attia J, Chasman DI, Ridker PM, Melander O, Mook-Kanamori DO, Harst PV, Cucca F, Schlessinger D, Hayward C, Spector TD, Jarvelin MR, Hennig BJ, Timpson NJ, Wei WQ, Smith JC, Xu Y, Matheny ME, Siew EE, Lindgren C, Herzig KH, Dedoussis G, Denny JC, Psaty BM, Howson JMM, Munroe PB, Newton-Cheh C, Caulfield MJ, Elliott P, Gaziano JM, Concato J, Wilson PWF, Tsao PS, Velez Edwards DR, Susztak K; Million Veteran Program, O'Donnell CJ, Hung AM, Edwards TL. Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. Nat Genet. 2019 Jan;51(1):51-62. doi: 10.1038/s41588-018-0303-9. Epub 2018 Dec 21. PubMed PMID: 30578418

Ray WA, Stein CM, Murray KT, Fuchs DC, Patrick SW, Daugherty J, Hall K, Cooper WO. Association of Antipsychotic Treatment With Risk of Unexpected Death Among Children and Youths. JAMA Psychiatry. 2019 Feb 1;76(2):162-171. doi: 10.1001/jamapsychiatry.2018.3421. PubMed PMID: 30540347

Aldrich MC, Mercaldo SF, Sandler KL, Blot WJ, Grogan EL, Blume JD. Evaluation of USPSTF Lung Cancer Screening Guidelines Among African American Adult Smokers. JAMA Oncol. 2019 Jun 27. doi: 10.1001/jamaoncol.2019.1402. [Epub ahead of print] Erratum in: JAMA Oncol. 2019 Aug 1;:. PubMed PMID: 31246249

Roumie CL, Chipman J, Min JY, Hackstadt AJ, Hung AM, Greevy RA Jr, Grijalva CG, Elasy T, Griffin MR. Association of Treatment With Metformin vs Sulfonylurea With Major Adverse Cardiovascular Events Among Patients With Diabetes and Reduced Kidney Function. JAMA. 2019 Sep 19:1-11. doi: 10.1001/jama.2019.13206. [Epub ahead of print] PubMed PMID: 31536102

Chen Z, Wen W, Beeghly-Fadiel A, Shu XO, Díez-Obrero V, Long J, Bao J, Wang J, Liu Q, Cai Q, Moreno V, Zheng W, Guo X. Identifying Putative Susceptibility Genes and Evaluating Their Associations with Somatic Mutations in Human Cancers. Am J Hum Genet. 2019 Sep 5;105(3):477-492. doi: 10.1016/j.ajhg.2019.07.006. Epub 2019 Aug 8. PubMed PMID: 31402092

Wiese AD, Griffin MR, Schaffner W, Stein CM, Greevy RA, Mitchel EF, Grijalva CG. Long-acting Opioid Use and the Risk of Serious Infections: A Retrospective Cohort Study. Clin Infect Dis. 2019 May 17;68(11):1862-1869. doi: 10.1093/cid/ciy809. PubMed PMID: 30239630
Yang JJ, Yu D, Xiang YB, Blot W, White E, Robien K, Sinha R, Park Y, Takata Y, Lazovich D, Gao YT, Zhang X, Lan Q, Bueno-de-Mesquita B, Johansson I, Tumino R, Riboli E, Tjønneland A, Skeie G, Quirós JR, Johansson M, Smith-Warner SA, Zheng W, Shu XO. Association of Dietary Fiber and Yogurt Consumption With Lung Cancer Risk: A Pooled Analysis. JAMA Oncol. 2019 Oct 24. doi: 10.1001/jamaoncol.2019.4107. [Epub ahead of print] PubMed PMID: 31647500

Unlu G, Gamazon ER, Qi X, Levic DS, Bastarache L, Denny JC, Roden DM, Mayzus I, Breyer M, Zhong X, Konkashbaev AI, Rzhetsky A, Knapik EW, Cox NJ. GRIK5 Genetically Regulated Expression Associated with Eye and Vascular Phenomes: Discovery through Iteration among Biobanks, Electronic Health Records, and Zebrafish. Am J Hum Genet. 2019 Mar 7;104(3):503-519. doi: 10.1016/j.ajhg.2019.01.017. Epub 2019 Feb 28. PubMed PMID: 30827500

Yang Y, Wu L, Shu XO, Cai Q, Shu X, Li B, Guo X, Ye F, Michailidou K, Bolla MK, Wang Q, Dennis J, Andrulis IL, Brenner H, Chenevix-Trench G, Campa D, Castelao JE, Gago-Dominguez M, Dörk T, Hollestelle A, Lophatananon A, Muir K, Neuhausen SL, Olsson H, Sandler DP, Simard J, Kraft P, Pharoah PDP, Easton DF, Zheng W, Long J. Genetically Predicted Levels of DNA Methylation Biomarkers and Breast Cancer Risk: Data From 228 951 Women of European Descent. J Natl Cancer Inst. 2020 Mar 1;112(3):295-304. doi: 10.1093/jnci/djz109. PubMed PMID: 31143935

Wiese AD, Huang X, Yu C, Mitchel EF, Kyaw MH, Griffin MR, Grijalva CG. Changes in Otitis Media Episodes and Pressure Equalization Tube Insertions Among Young Children Following Introduction of the 13-Valent Pneumococcal Conjugate Vaccine: A Birth Cohort-based Study. Clin Infect Dis. 2019 Nov 27;69(12):2162-2169. doi: 10.1093/cid/ciz142. PubMed PMID: 30770533
 

Top Ten: 2018

Davenport JR, Su T, Zhao Z, Coleman HG, Smalley WE, Ness RM, Zheng W, Shrubsole MJ. Modifiable lifestyle factors associated with risk of sessile serrated polyps, conventional adenomas and hyperplastic polyps. Gut. 2018;67(3):456–465. PMID 27852795.

Wiese AD, Griffin MR, Schaffner W, Stein CM, Greevy RA, Mitchel EF, Grijalva CG. Opioid Analgesic Use and Risk for Invasive Pneumococcal Diseases: A Nested Case-Control Study. Ann Intern Med. 2018 Mar 20;168(6):396–404. PMID: 29435555.

Ray WA, Chung CP, Murray KT, Smalley WE, Daugherty JR, Dupont WD, Stein CM. Association of Oral Anticoagulants and Proton Pump Inhibitor Cotherapy With Hospitalization for Upper Gastrointestinal Tract Bleeding. JAMA. 2018 04;320(21):2221–2230. PMID: 30512099.

Girard TD, Thompson JL, Pandharipande PP, Brummel NE, Jackson JC, Patel MB, Hughes CG, Chandrasekhar R, Pun BT, Boehm LM, Elstad MR, Goodman RB, Bernard GR, Dittus RS, Ely EW. Clinical phenotypes of delirium during critical illness and severity of subsequent long-term cognitive impairment: a prospective cohort study. Lancet Respir Med. 2018 Mar;6(3):213–222. PMID: 29508705.

Wu L, Shi W, Long J, and 206 others, Easton DF, Chenevix-Trench G, Zheng W. A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer. Nat Genet. 2018 Jun 18. doi: 10.1038/s41588-018-0132-x. [Epub ahead of print] PubMed PMID: 29915430.

Girard TD, Exline MC, Carson SS, Hough CL, Rock P, Gong MN, Douglas IS, Malhotra A, Owens RL, Feinstein DJ, Khan B, Pisani MA, Hyzy RC, Schmidt GA, Schweickert WD, Hite RD, Bowton DL, Masica AL, Thompson JL, Chandrasekhar R, Pun BT, Strength C, Boehm LM, Jackson JC, Pandharipande PP, Brummel NE, Hughes CG, Patel MB, Stollings JL, Bernard GR, Dittus RS, Ely EW, MIND-USA Investigators. Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness. N Engl J Med. 2018 27;379(26):2506–2516. PMID: 30346242.

Yu D, Zheng W, Cai H, Xiang YB, Li H, Gao YT, Shu XO. Long-term Diet Quality and Risk of Type 2 Diabetes Among Urban Chinese Adults. Diabetes Care. 2018Apr;41(4):723-730. doi: 10.2337/dc17-1626. Epub 2017 Dec 21. PubMed PMID:29269510.

Liu Y, Shu XO, Wen W, Saito E, Rahman MS, Tsugane S, Tamakoshi A, Xiang YB, Yuan JM, Gao YT, Tsuji I, Kanemura S, Nagata C, Shin MH, Pan WH, Koh WP, Sawada N, Cai H, Li HL, Tomata Y, Sugawara Y, Wada K, Ahn YO, Yoo KY, Ashan H, Chia KS, Boffetta P, Inoue M, Kang D, Potter JD, Zheng W. Association of leisure-time physical activity with total and cause-specific mortality: a pooled analysis of nearly a half million adults in the Asia Cohort Consortium. Int J Epidemiol. 2018 Feb 27. doi: 10.1093/ije/dyy024. [Epub ahead of print]PMID: 29490039.

Yu D, Zheng W, Johansson M, Lan Q, Park Y, White E, Matthews CE, Sawada N, GaoYT, Robien K, Sinha R, Langhammer A, Kaaks R, Giovannucci EL, Liao LM, Xiang YB, Lazovich D, Peters U, Zhang X, Bueno-de-Mesquita B, Willett WC, Tsugane S, TakataY, Smith-Warner SA, Blot W, Shu XO. Overall and Central Obesity and Risk of Lung Cancer: A Pooled Analysis. J Natl Cancer Inst. 2018 Aug 1;110(8):831-842. doi:10.1093/jnci/djx286. PubMed PMID: 29518203.

Turi KN, Shankar J, Anderson LJ, Rajan D, Gaston K, Gebretsadik T, Das SR, Stone C, Larkin EK, Rosas-Salazar C, Brunwasser SM, Moore ML, Peebles RS, Hartert TV. Infant Viral Respiratory Infection Nasal Immune-Response Patterns and Their Association with Subsequent Childhood Recurrent Wheeze. Am J Respir Crit Care Med. 2018 Oct 15;198(8):1064–1073. PMID: 29733679.

Top Ten: 2017

Yang JJ, Yu D, Takata Y, Smith-Warner SA, Blot W, White E, Robien K, Park Y, Xiang Y-B, Sinha R, Lazovich D, Stampfer M, Tumino R, Aune D, Overvad K, Liao L, Zhang X, Gao Y-T, Johansson M, Willett W, Zheng W, Shu X-O. Dietary Fat Intake and Lung Cancer Risk: A Pooled Analysis. J Clin Oncol. 2017 Jul 25;JCO2017733329. PMID: 28742456

Yu D, Zheng W, Cai H, Xiang Y-B, Li H, Gao Y-T, Shu X-O. Long-term Diet Quality and Risk of Type 2 Diabetes Among Urban Chinese Adults. Diabetes Care. 2017 Dec 21; PMID: 29269510

Williams DJ, Edwards KM, Self WH, Zhu Y, Arnold SR, McCullers JA, Ampofo K, Pavia AT, Anderson EJ, Hicks LA, Bramley AM, Jain S, Grijalva CG. Effectiveness of β-Lactam Monotherapy vs Macrolide Combination Therapy for Children Hospitalized With Pneumonia. JAMA Pediatr. 2017 Dec 1;171(12):1184-1191. doi: 10.1001/jamapediatrics.2017.3225. PubMed PMID: 29084336

Cooper WO, Guillamondegui O, Hines OJ, Hultman CS, Kelz RR, Shen P, Spain DA, Sweeney JF, Moore IN, Hopkins J, Horowitz IR, Howerton RM, Meredith JW, Spell NO, Sullivan P, Domenico HJ, Pichert JW, Catron TF, Webb LE, Dmochowski RR, Karrass J, Hickson GB. Use of Unsolicited Patient Observations to Identify Surgeons With Increased Risk for Postoperative Complications. JAMA Surg. 2017 Jun 1;152(6):522–529. PMID: 28199477 

Cui Y, Shu X-O, Li H-L, Yang G, Wen W, Gao Y-T, Cai Q, Rothman N, Yin H-Y, Lan Q, Xiang Y-B, Zheng W. Prospective study of urinary prostaglandin E2 metabolite and pancreatic cancer risk. Int J Cancer. 2017 Dec 15;141(12):2423–2429. PMID: 28815606

Wang N, Lu Y, Khankari NK, Long J, Li H-L, Gao J, Gao Y-T, Xiang Y-B, Shu X-O, Zheng W. Evaluation of genetic variants in association with colorectal cancer risk and survival in Asians. Int J Cancer. 2017 Sep 15;141(6):1130–1139. PMID: 28567967

Akwo EA, Kabagambe EK, Wang TJ, Harrell FE, Blot WJ, Mumma M, Gupta DK, Lipworth L. Heart Failure Incidence and Mortality in the Southern Community Cohort Study. Circ Heart Fail. 2017 Mar;10(3). PMID: 28255010

Achten NB, Wu P, Bont L, Blanken MO, Gebretsadik T, Chappell JD, Wang L, Yu C, Larkin EK, Carroll KN, Anderson LJ, Moore ML, Sloan CD, Hartert TV. Interference Between Respiratory Syncytial Virus and Human Rhinovirus Infection in Infancy. J Infect Dis. 2017 Mar 24; PMID: 28368456

Giri A, Edwards TL, Hartmann KE, Torstenson ES, Wellons M, Schreiner PJ, Velez Edwards DR. African genetic ancestry interacts with body mass index to modify risk for uterine fibroids. PLoS Genet. 2017 Jul;13(7):e1006871. PMCID: PMID: 28715450

Lang Kuhs KA, Kreimer AR, Trivedi S, Holzinger D, Pawlita M, Pfeiffer RM, Gibson SP, Schmitt NC, Hildesheim A, Waterboer T, Ferris RL. Human papillomavirus 16 E6 antibodies are sensitive for human papillomavirus-driven oropharyngeal cancer and are associated with recurrence. Cancer. 2017 Nov 15;123(22):4382–4390. PMID: 28950407 

 

Top Ten: 2016

Ray WA, Chung CP, Murray KT, Hall K, Stein CM. Prescription of Long-Acting Opioids and Mortality in Patients With Chronic Noncancer Pain. JAMA. 2016 Jun 14;315(22):2415–2423. PMID: 27299617.  

Davenport JR, Su T, Zhao Z, Coleman HG, Smalley WE, Ness RM, Zheng W, Shrubsole MJ. Modifiable lifestyle factors associated with risk of sessile serrated polyps, conventional adenomas and hyperplastic polyps. Gut. 2016 Nov 15 [Epub ahead of print] PMID: 27852795. 

Khankari NK, Shu X-O, Wen W, Kraft P, Lindström S, Peters U, Schildkraut J, Schumacher F, Bofetta P, Risch A, Bickeböller H, Amos CI, Easton D, Eeles RA, Gruber SB, Haiman CA, Hunter DJ, Chanock SJ, Pierce BL, Zheng W, Colorectal Transdisciplinary Study (CORECT), Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE), Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE), Transdisciplinary Research in Cancer of the Lung (TRICL). Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses. PLoS Med. 2016 Sep;13(9):e1002118. PMCID: PMC5012582.

Munro HM, Tarone RE, Wang TJ, Blot WJ. Menthol and Nonmenthol Cigarette Smoking All-Cause Deaths, Cardiovascular Disease Deaths, and Other Causes of Death Among Blacks and Whites. Circulation. 2016 May 10;133(19):1861–1866. PMID: 27022064.

Guo Y, Warren Andersen S, Shu X-O, Michailidou K, Bolla MK, Wang Q, Garcia-Closas M, Milne RL, Schmidt MK, Chang-Claude J, Dunning A, Bojesen SE, Ahsan H, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Beeghly-Fadiel A, Benitez J, Bogdanova NV, Bonanni B, Børresen-Dale A-L, Brand J, Brauch H, Brenner H, Brüning T, Burwinkel B, Casey G, Chenevix-Trench G, Couch FJ, Cox A, Cross SS, Czene K, Devilee P, Dörk T, Dumont M, Fasching PA, Figueroa J, Flesch-Janys D, Fletcher O, Flyger H, Fostira F, Gammon M, Giles GG, Guénel P, Haiman CA, Hamann U, Hooning MJ, Hopper JL, Jakubowska A, Jasmine F, Jenkins M, John EM, Johnson N, Jones ME, Kabisch M, Kibriya M, Knight JA, Koppert LB, Kosma V-M, Kristensen V, Le Marchand L, Lee E, Li J, Lindblom A, Luben R, Lubinski J, Malone KE, Mannermaa A, Margolin S, Marme F, McLean C, Meijers-Heijboer H, Meindl A, Neuhausen SL, Nevanlinna H, Neven P, Olson JE, Perez JIA, Perkins B, Peterlongo P, Phillips K-A, Pylkäs K, Rudolph A, Santella R, Sawyer EJ, Schmutzler RK, Seynaeve C, Shah M, Shrubsole MJ, Southey MC, Swerdlow AJ, Toland AE, Tomlinson I, Torres D, Truong T, Ursin G, Van Der Luijt RB, Verhoef S, Whittemore AS, Winqvist R, Zhao H, Zhao S, Hall P, Simard J, Kraft P, Pharoah P, Hunter D, Easton DF, Zheng W. Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.PLoS Med. 2016 Aug;13(8):e1002105. PMCID: PMC4995025.  

Cai H, Ye F, Michel A, Murphy G, Sasazuki S, Taylor PR, Qiao Y-L, Park SK, Yoo K-Y, Jee SH, Cho ER, Kim J, Chen S-C, Abnet CC, Tsugane S, Cai Q, Shu X-O, Zheng W, Pawlita M, Epplein M. Helicobacter pylori blood biomarker for gastric cancer risk in East Asia. Int J Epidemiol. 2016 May 11;dyw078. PMID: 27170766.  

Sonderman JS, Bethea TN, Kitahara CM, Patel AV, Harvey C, Knutsen SF, Park Y, Park S-Y, Fraser GE, Teras LR, Purdue MP, Stolzenberg-Solomon RZ, Gillanders EM, Palmer JR, Kolonel LN, Blot WJ. Multiple Myeloma Mortality in Relation to Obesity Among African Americans. J Natl Cancer Inst. 2016 Oct;108(10). PMID: 27147231. 

Sudenga SL, Ingles DJ, Pierce Campbell CM, Lin HY, Fulp W, Messina JL, Stoler MH, Abrahamsen M, Villa LL, Lazcano-Ponce E, and Giuliano AR. Genital human papillomavirus (HPV) infection progression to external genital lesions: the HIM Study. European Urology. 2016; 69:166-73. PMID:26051441. 

Ray WA, Chung CP, Murray KT, Smalley WE, Daugherty JR, Dupont WD, Stein CM. Association of Proton Pump Inhibitors With Reduced Risk of Warfarin-Related Serious Upper Gastrointestinal Bleeding.Gastroenterology. 2016 Dec;151(6):1105–1112.e10. PMCID: PMC5124401.  

 Ren HG, Luu HN, Cai H, Xiang YB, Steinwandel M, Gao YT, Hargreaves M, Zheng W, Blot WJ, Long JR, Shu XO. Oral health and risk of colorectal cancer: results from three cohort studies and a meta-analysis. Ann Oncol. 2016 May 23;mdw172. PMID: 27217540. 

 

Top Ten: 2015

• Yu D, Sonderman J, Buchowski MS, McLaughlin JK, Shu X-O, Steinwandel M, Signorello LB, Zhang X, Hargreaves MK, Blot WJ, Zheng W. Healthy Eating and Risks of Total and Cause-Specific Death among Low-Income Populations of African-Americans and Other Adults in the Southeastern United States: A Prospective Cohort Study. PLoS Med. 2015 May;12(5):e1001830; discussion e1001830. PMCID: PMC4444091.
• Luu HN, Blot WJ, Xiang Y-B, Cai H, Hargreaves MK, Li H, Yang G, Signorello L, Gao Y-T, Zheng W, Shu X-O. Prospective evaluation of the association of nut/peanut consumption with total and cause-specific mortality. JAMA Intern Med. 2015 May;175(5):755–766. PMCID: PMC4474488.
• Grijalva CG, Zhu Y, Williams DJ, Self WH, Ampofo K, Pavia AT, Stockmann CR, McCullers J, Arnold SR, Wunderink RG, Anderson EJ, Lindstrom S, Fry AM, Foppa IM, Finelli L, Bramley AM, Jain S, Griffin MR, Edwards KM. Association Between Hospitalization With Community-Acquired Laboratory-Confirmed Influenza Pneumonia and Prior Receipt of Influenza Vaccination.JAMA. 2015 Oct 13;314(14):1488–1497. PMID: 26436611 PMCID: PMC4688454.
• Fowke JH, McLerran DF, Gupta PC, He J, Shu XO, Ramadas K, Tsugane S, Inoue M, Tamakoshi A, Koh WP, Nishino Y, Tsuji I, Ozasa K, Yuan JM, Tanaka H, Ahn YO, Chen CJ, Sugawara Y, Yoo KY, Ahsan H, Pan WH, Pednekar M, Gu D, Xiang YB, Sauvaget C, Sawada N, Wang R, Kakizaki M, Tomata Y, Ohishi W, Butler LM, Oze I, Kim DH, You SL, Park SK, Parvez F, Chuang SY, Chen Y, Lee JE, Grant E, Rolland B, Thornquist M, Feng Z, Zheng W, Boffetta P, Sinha R, Kang D, Potter JD. Associations of body mass index, smoking, and alcohol consumption with prostate cancer mortality in the Asia Cohort Consortium. Am J Epidemiol. 2015 Sep 1;182(5):381-9 PMCID: PMC4643758.
• Jain NB, Ayers GD, Peterson EN, Harris MB, Morse L, O’Connor KC, Garshick E. Traumatic spinal cord injury in the United States, 1993-2012. JAMA. 2015 Jun 9;313(22):2236–2243. PMCID: PMC4712685.
• Zhang B, Shu X-O, Delahanty RJ, Zeng C, Michailidou K, Bolla MK, Wang Q, Dennis J, Wen W, Long J, Li C, Dunning AM, Chang-Claude J, Shah M, Perkins BJ, Czene K, Darabi H, Eriksson M, Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, Lambrechts D, Neven P, Wildiers H, Floris G, Schmidt MK, Rookus MA, van den Hurk K, de Kort WLAM, Couch FJ, Olson JE, Hallberg E, Vachon C, Rudolph A, Seibold P, Flesch-Janys D, Peto J, Dos-Santos-Silva I, Fletcher O, Johnson N, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Li J, Humphreys K, Brand J, Guénel P, Truong T, Cordina-Duverger E, Menegaux F, Burwinkel B, Marme F, Yang R, Surowy H, Benitez J, Zamora MP, Perez JIA, Cox A, Cross SS, Reed MWR, Andrulis IL, Knight JA, Glendon G, Tchatchou S, Sawyer EJ, Tomlinson I, Kerin MJ, Miller N, Chenevix-Trench G, kConFab Investigators, Australian Ovarian Study Group, Haiman CA, Henderson BE, Schumacher F, Marchand LL, Lindblom A, Margolin S, Hooning MJ, Martens JWM, Tilanus-Linthorst MMA, Collée JM, Hopper JL, Southey MC, Tsimiklis H, Apicella C, Slager S, Toland AE, Ambrosone CB, Yannoukakos D, Giles GG, Milne RL, McLean C, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, Swerdlow AJ, Ashworth A, Orr N, Jones M, Figueroa J, Garcia-Closas M, Brinton L, Lissowska J, Dumont M, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Brauch H, Brüning T, Ko Y-D, Peterlongo P, Manoukian S, Bonanni B, Radice P, Bogdanova N, Antonenkova N, Dörk T, Mannermaa A, Kataja V, Kosma V-M, Hartikainen JM, Devilee P, Seynaeve C, Van Asperen CJ, Jakubowska A, Lubiński J, Jaworska-Bieniek K, Durda K, Hamann U, Torres D, Schmutzler RK, Neuhausen SL, Anton-Culver H, Kristensen VN, Grenaker Alnæs GI, DRIVE Project, Pierce BL, Kraft P, Peters U, Lindstrom S, Seminara D, Burgess S, Ahsan H, Whittemore AS, John EM, Gammon MD, Malone KE, Tessier DC, Vincent D, Bacot F, Luccarini C, Baynes C, Ahmed S, Maranian M, Healey CS, González-Neira A, Pita G, Alonso MR, Álvarez N, Herrero D, Pharoah PDP, Simard J, Hall P, Hunter DJ, Easton DF, Zheng W. Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian Randomization. J Natl Cancer Inst. 2015 Nov;107(11). PMCID: PMC4643630.
• Shu X-O, Li H, Yang G, Gao J, Cai H, Takata Y, Zheng W, Xiang Y-B. Cohort Profile: The Shanghai Men’s Health Study. Int J Epidemiol. 2015 Jun;44(3):810–818. PMCID: PMC4521127.
• Zeng C, Wen W, Morgans AK, Pao W, Shu X-O, Zheng W. Disparities by Race, Age, and Sex in the Improvement of Survival for Major Cancers: Results From the National Cancer Institute Surveillance, Epidemiology, and End Results (SEER) Program in the United States, 1990 to 2010. JAMA Oncol. 2015 Apr;1(1):88–96. PMCID: PMC4523124.
• Ray WA, Chung CP, Murray KT, Cooper WO, Hall K, Stein CM. Out-of-hospital mortality among patients receiving methadone for noncancer pain. JAMA Intern Med. 2015 Mar;175(3):420–427. PMCID: PMC4346542.
•  Luu HN, Wen W, Li H, Dai Q, Yang G, Cai Q, Xiang Y-B, Gao Y-T, Zheng W, Shu X-O. Are dietary antioxidant intake indices correlated to oxidative stress and inflammatory marker levels? Antioxid Redox Signal. 2015 Apr 10;22(11):951–959. PMCID: PMC4376488.

       

Top Ten: 2014

• Zheng W, McLerran DF, Rolland BA, Fu Z, Boffetta P, He J, Gupta PC, Ramadas K, Tsugane S, Irie F, Tamakoshi A, Gao Y-T, Koh W-P, Shu X-O, Ozasa K, Nishino Y, Tsuji I, Tanaka H, Chen C-J, Yuan J-M, Ahn Y-O, Yoo K-Y, Ahsan H, Pan W-H, Qiao Y-L, Gu D, Pednekar MS, Sauvaget C, Sawada N, Sairenchi T, Yang G, Wang R, Xiang Y-B, Ohishi W, Kakizaki M, Watanabe T, Oze I, You S-L, Sugawara Y, Butler LM, Kim D-H, Park SK, Parvez F, Chuang S-Y, Fan J-H, Shen C-Y, Chen Y, Grant EJ, Lee JE, Sinha R, Matsuo K, Thornquist M, Inoue M, Feng Z, Kang D, Potter JD. Burden of total and cause-specific mortality related to tobacco smoking among adults aged ≥ 45 years in Asia: a pooled analysis of 21 cohorts. PLoS Med. 2014 Apr;11(4):e1001631. PMCID: PMC3995657

• Fowke JH, Howard L, Andriole GL, Freedland SJ. Alcohol intake increases high-grade prostate cancer risk among men taking dutasteride in the REDUCE trial. Eur Urol. 2014 Dec;66(6):1133–1138. PMCID: PMC4127165

• Friedman DL, Chen L, Wolden S, Buxton A, McCarten K, FitzGerald TJ, Kessel S, De Alarcon PA, Chen AR, Kobrinsky N, Ehrlich P, Hutchison RE, Constine LS, Schwartz CL. Dose-intensive response-based chemotherapy and radiation therapy for children and adolescents with newly diagnosed intermediate-risk hodgkin lymphoma: a report from the Children’s Oncology Group Study AHOD0031. J Clin Oncol Off J Am Soc Clin Oncol. 2014 Nov 10;32(32):3651–3658. PMCID: PMC4220044

• Cai Q, Zhang B, Sung H, Low S-K, Kweon S-S, Lu W, Shi J, Long J, Wen W, Choi J-Y, Noh D-Y, Shen C-Y, Matsuo K, Teo S-H, Kim MK, Khoo US, Iwasaki M, Hartman M, Takahashi A, Ashikawa K, Matsuda K, Shin M-H, Park MH, Zheng Y, Xiang Y-B, Ji B-T, Park SK, Wu P-E, Hsiung C-N, Ito H, Kasuga Y, Kang P, Mariapun S, Ahn SH, Kang HS, Chan KYK, Man EPS, Iwata H, Tsugane S, Miao H, Liao J, Nakamura Y, Kubo M, DRIVE GAME-ON Consortium, Delahanty RJ, Zhang Y, Li B, Li C, Gao Y-T, Shu X-O, Kang D, Zheng W. Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1. Nat Genet. 2014 Aug;46(8):886–890. PMCID: PMC4127632

• Zhang B, Jia W-H, Matsuda K, Kweon S-S, Matsuo K, Xiang Y-B, Shin A, Jee SH, Kim D-H, Cai Q, Long J, Shi J, Wen W, Yang G, Zhang Y, Li C, Li B, Guo Y, Ren Z, Ji B-T, Pan Z-Z, Takahashi A, Shin M-H, Matsuda F, Gao Y-T, Oh JH, Kim S, Ahn Y-O, Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO), Chan AT, Chang-Claude J, Slattery ML, Colorectal Transdisciplinary (CORECT) Study, Gruber SB, Schumacher FR, Stenzel SL, Colon Cancer Family Registry (CCFR), Casey G, Kim H-R, Jeong J-Y, Park JW, Li H-L, Hosono S, Cho S-H, Kubo M, Shu X-O, Zeng Y-X, Zheng W. Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. Nat Genet. 2014 Jun;46(6):533–542. PMCID: PMC4068797

• Cui Y, Deming-Halverson SL, Beeghly-Fadiel A, Lipworth L, Shrubsole MJ, Fair AM, Shu X-O, Zheng W. Interactions of hormone replacement therapy, body weight, and bilateral oophorectomy in breast cancer risk. Clin Cancer Res Off J Am Assoc Cancer Res. 2014 Mar 1;20(5):1169–1178. PMCID: PMC3972811

• Grijalva CG. Decrease in antibiotic use, an added benefit of PCVs. Lancet Infect Dis. 2014 Mar;14(3):175–177. PMID: 24287185

• Grijalva CG, Griffin MR, Edwards KM, Williams JV, Gil AI, Verastegui H, Hartinger SM, Vidal JE, Klugman KP, Lanata CF. Cohort profile: The study of respiratory pathogens in Andean children. Int J Epidemiol. 2014 Aug;43(4):1021–1030. PMCID: PMC4121548

• Kodaman N, Pazos A, Schneider BG, Piazuelo MB, Mera R, Sobota RS, Sicinschi LA, Shaffer CL, Romero-Gallo J, de Sablet T, Harder RH, Bravo LE, Peek RM, Wilson KT, Cover TL, Williams SM, Correa P. Human andHelicobacter pylori coevolution shapes the risk of gastric disease. Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1455–1460. PMCID: PMC3910595

• Yu D, Zhang X, Xiang Y-B, Yang G, Li H, Gao Y-T, Zheng W, Shu X-O. Adherence to dietary guidelines and mortality: a report from prospective cohort studies of 134,000 Chinese adults in urban Shanghai. Am J Clin Nutr. 2014 Aug;100(2):693–700. PMCID: PMC4095665 
  
   

Top Ten: 2013

• Griffin MR, Zhu Y, Moore MR, Whitney CG, Grijalva CG.  U.S. hospitalizations for pneumonia after a decade of pneumococcal vaccination.  N Engl J Med. 2013 Jul 11;369(2):155-63. PMID: 23841730.

• Zheng W, Zhang B, Cai Q, Sung H, Michailidou K, Shi J, Choi JY, Long J, Dennis J, Humphreys MK, Wang Q, Lu W, Gao YT, Li C, Cai H, Park SK, Yoo KY, Noh DY, Han W, Dunning AM, Benitez J, Vincent D, Bacot F, Tessier D, Kim SW, Lee MH, Lee JW, Lee JY, Xiang YB, Zheng Y, Wang W, Ji BT, Matsuo K, Ito H, Iwata H, Tanaka H, Wu AH, Tseng CC, Van Den Berg D, Stram DO, Teo SH, Yip CH, Kang IN, Wong TY, Shen CY, Yu JC, Huang CS, Hou MF, Hartman M, Miao H, Lee SC, Putti TC, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Sangrajrang S, Shen H, Chen K, Wu PE, Ren Z, Haiman CA, Sueta A, Kim MK, Khoo US, Iwasaki M, Pharoah PD, Wen W, Hall P, Shu XO, Easton DF, Kang D.  Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls.  Hum Mol Genet. 2013 Jun 15;22(12):2539-50. PMID: 23535825; PMCID: PMC3658167.

• Pandharipande PP, Girard TD, Jackson JC, Morandi A, Thompson JL, Pun BT, Brummel NE, Hughes CG, Vasilevskis EE, Shintani AK, Moons KG, Geevarghese SK, Canonico A, Hopkins RO, Bernard GR, Dittus RS, Ely EW; BRAIN-ICU Study Investigators.  Long-term cognitive impairment after critical illness.  N Engl J Med. 2013 Oct 3;369(14):1306-16. PMID: 24088092.
• Long J, Delahanty RJ, Li G, Gao YT, Lu W, Cai Q, Xiang YB, Li C, Ji BT, Zheng Y, Ali S, Shu XO, Zheng W.  A Common Deletion in the APOBEC3 Genes and Breast Cancer Risk . J Natl Cancer Inst. 2013 Apr 17;105(8):573-9. PMID: 23411593; PMCID: PMC3627644.

• Yang G, Shu XO, Li HL, Chow WH, Wen W, Xiang YB, Zhang X, Cai H, Ji BT, Gao YT, Zheng W.  Prediagnosis soy food consumption and lung cancer survival in women.  J Clin Oncol. 2013 Apr 20;31(12):1548-53. PMID: 23530109; PMCID: PMC3625711.

• Samuels DC, Li C, Li B, Song Z, Torstenson E, Boyd Clay H, Rokas A, Thornton-Wells TA, Moore JH, Hughes TM, Hoffman RD, Haines JL, Murdock DG, Mortlock DP, Williams SM*.  Recurrent tissue-specific mtDNA mutations are common in humans . PLoS Genet. 2013 Nov;9(11):e1003929. PMID: 24244193; PMCID: PMC3820769.
• Kiage JN, Merrill PD, Robinson CJ, Cao Y, Malik TA, Hundley BC, Lao P, Judd SE, Cushman M, Howard VJ, Kabagambe EK.  Intake of trans fat and all-cause mortality in the Reasons for Geographical and Racial Differences in Stroke (REGARDS) cohort.  Am J Clin Nutr. 2013 May;97(5):1121-8. PMID: 23553155; PMCID: PMC3628378.

• Ma X, Zhang B, Zheng W.  Genetic variants associated with colorectal cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence.  Gut. 2013 Aug 14. PMID: 23946381.

• Legrys VA, Funk MJ, Lorenz CE, Giri A, Jackson RD, Manson JE, Schectman R, Edwards TL, Heiss G, Hartmann KE.  Subclinical hypothyroidism and risk for incident myocardial infarction among postmenopausal women . J Clin Endocrinol Metab. 2013 Jun;98(6):2308-17. PMID: 23539723; PMCID: PMC3667262.

• Sampson UK, Edwards TL, Jahangir E, Munro H, Wariboko M, Wassef MG, Fazio S, Mensah GA, Kabagambe EK, Blot WJ, Lipworth L.  Factors Associated With the Prevalence of Hypertension in the Southeastern United States: Insights From 69 211 Blacks and Whites in the Southern Community Cohort Study.  Circ Cardiovasc Qual Outcomes. 2013 Dec 23. PMID: 24365671.

 

Top Ten 2012

• Jia WH, Zhang B, Matsuo K, Shin A, Xiang YB, Jee SH, Kim DH, Ren Z, Cai Q, Long J, Shi J, Wen W, Yang G, Delahanty RJ; Colon Cancer Family Registry (CCFR), Ji BT, Pan ZZ, Matsuda F, Gao YT, Oh JH, Ahn YO, Park EJ, Li HL, Park JW, Jo J, Jeong JY, Hosono S, Casey G, Peters U, Shu XO, Zeng YX, Zheng W;  Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO). Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer. Nat Genet 45(2):191-6. Epub 2012 Dec 23. PMC3679924

• Signorello LB, Mulvihill JJ, Green DM, Munro HM, Stovall M, Weathers RE, Mertens AC, Whitton JA, Robison LL, Boice JD Jr.  Congenital anomalies in the children of cancer survivors: a report from the childhood cancer survivor study.  J Clin Oncol 2012 30(3):239-45. PMC3269950

• Wen W, Cho YS, Zheng W, Dorajoo R, Kato N, Qi L, Chen CH, Delahanty RJ, Okada Y, Tabara Y, Gu D, Zhu D, Haiman CA, Mo Z, Gao YT, Saw SM, Go MJ, Takeuchi F, Chang LC, Kokubo Y, Liang J, Hao M, Le Marchand L, Zhang Y, Hu Y, Wong TY, Long J, Han BG, Kubo M, Yamamoto K, Su MH, Miki T, Henderson BE, Song H, Tan A, He J, Ng DP, Cai Q, Tsunoda T, Tsai FJ, Iwai N, Chen GK, Shi J, Xu J, Sim X, Xiang YB, Maeda S, Ong RT, Li C, Nakamura Y, Aung T, Kamatani N, Liu JJ, Lu W, Yokota M, Seielstad M, Fann CS; The Genetic Investigation of Anthropometric Traits (GIANT) Consortium, Wu JY, Lee JY, Hu FB, Tanaka T, Tai ES, Shu XO.  Meta-analysis identifies common variants associated with body mass index in East Asians.  Nat Genet 2012 44(3):307-311. PMCID:PMC3288728 

• Winther JF, Olsen JH, Wu H, Shyr Y, Mulvihill JJ, Stovall M, Nielsen A, Schmiegelow M, Boice JD Jr.  Genetic disease in the children of Danish survivors of childhood and adolescent cancer.  J Clin Oncol 2012 30:27-33. PMCID:PMC3255559

• Roumie CL, Hung AH, Greevy RA, Grijalva CG, Liu X, Murff HJ, Elasy TA, Griffin MR.  Comparative effectiveness of sulfonylurea and metformin monotherapy on cardiovascular events in type 2 diabetes mellitus. A cohort study.  Ann Intern Med 2012 157(9):601-610. PMID:23128859

• Shu XO, Long J, Lu W, Li C, Chen WY, Delahanty R, Cheng J, Cai H, Zheng Y, Shi J, Gu K, Wang WJ, Kraft P, Gao YT, Cai Q, Zheng W.  Novel genetic markers of breast cancer identified by a genome-wide association study . Cancer Res 2012 72(5):1182-9. PMCID:PMC3294129

• Zhang W, Shu XO, Li H, Yang G, Cai H, Ji BT, Gao J, Gao YT, Zheng W, Xiang YB.  Vitamin intake and liver cancer risk: a report from two cohort studies in China.  J Natl Cancer Inst 2012 104(15):1173-81. PMCID: PMC3611811

• Long J, Cai Q, Sung H, Shi J, Zhang B, Choi JY, Wen W, Delahanty RJ, Lu W, Gao YT, Shen H, Park SK, Chen K, Shen CY, Ren Z, Haiman CA, Matsuo K, Kim MK, Khoo US, Iwasaki M, Zheng Y, Xiang YB, Gu K, Rothman N, Wang W, Hu Z, Liu Y, Yoo KY,Noh DY, Han BG, Lee MH, Zheng H, Zhang L, Wu PE, Shieh YL, Chan SY, Wang S, Xie X, Kim SW, Henderson BE, Le Marchand L, Ito H, Kasuga Y, Ahn SH, Kang HS, Chan KY, Iwata H, Tsugane S, Li C, Shu XO, Kang DH, Zheng W.  Genome-wide association study in East Asians identifies novel susceptibility loci for breast cancer. PLoS Genet 2012 8(2):e1002532. PMCID: PMC3285588

• Cho YS, Chen CH, Hu C, Long J, Ong RT, Sim X, Takeuchi F, Wu Y, Go MJ, Yamauchi T, Chang YC, Kwak SH, Ma RC, Yamamoto K, Adair LS, Aung T, Cai Q, Chang LC, Chen YT, Gao Y, Hu FB, Kim HL, Kim S, Kim YJ, Lee JJ, Lee NR, Li Y, Liu JJ, Lu W, Nakamura J, Nakashima E, Ng DP, Tay WT, Tsai FJ, Wong TY, Yokota M, Zheng W, Zhang R, Wang C, So WY, Ohnaka K, Ikegami H, Hara K, Cho YM, Cho NH, Chang TJ, Bao Y, Hedman ÅK, Morris AP, McCarthy MI; DIAGRAM Consortium; MuTHER Consortium, Takayanagi R, Park KS, Jia W, Chuang LM, Chan JC, Maeda S, Kadowaki T, Lee JY, Wu JY, Teo YY, Tai ES, Shu XO, Mohlke KL, Kato N, Han BG, Seielstad M.  Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in East Asians.  Nat Genet 2012 4(1):67-72. PMCID: PMC3582398          (co-first & co-last authors)

• Murff HJ, Shrubsole MJ, Cai Q, Smalley WE, Dai Q, Milne GL, Ness RM, Zheng W.  Dietary intake of PUFAs and colorectal polyp risk. Am J Clin Nutr 2012 95(3):703-12. PMCID:PMC3278245

 

Top Ten: 2011

• Zheng W, McLerran DF, Rolland B, Zhang X, Inoue M, Matsuo K, He J, Gupta PC, Ramadas K, Tsugane S, Irie F, Tamakoshi A, Gao YT, Wang R, Shu XO, Tsuji I, Kuriyama S, Tanaka H, Satoh H, Chen CJ, Yuan JM, Yoo KY, Ahsan H, Pan WH, Gu D, Pednekar MS, Sauvaget C, Sasazuki S, Sairenchi T, Yang G, Xiang YB, Nagai M, Suzuki T, Nishino Y, You SL, Koh WP, Park SK, Chen Y, Shen CY, Thornquist M, Feng Z, Kang D, Boffetta P, Potter JD.  Association between body-mass index and risk of death in more than 1 million Asians.  N Engl J Med 2011, 364(8):719-29

• Blot WJ, Cohen SS, Aldrich M, McLaughlin JK, Hargreaves MK, Signorello LB.  Lung cancer risk among smokers of menthol cigarettes.  J Natl Cancer Inst 2011, 103(10):810-6

• Murff HJ, FitzHenry F, Matheny ME, Gentry N, Kotter KL, Crimin K, Dittus RS, Rosen AK, Elkin PL, Brown SH, Speroff T.  Automated identification of postoperative complications within an electronic medical record using natural language  processing.  JAMA 2011, 306(8): 848-55

• Epplein M, Zheng Y, Zheng W, Chen Z, Gu K, Penson D, Lu W, Shu XO. Quality of life after breast cancer diagnosis and survival.  J Clin Oncol 2011, 29(4):406-12

• Zhang B, Beeghly-Fadiel A, Long J, Zheng W.  Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence.  Lancet Oncol 2011, 12(5):477-88

• Miller EK, Williams JV, Gebretsadik T, Carroll KN, Dupont WD, Mohamed YA, Morin LL, Heil L, Minton PA, Woodward K, Liu Z, Hartert TV.  Host factors and viral factors associated with severity of human rhinovirus infant respiratory illness.  J Allergy Clin Immunol 2011, 127(4):883-91

• Cai Q, Wen W, Qu S, Li G, Egan KM, Chen K, Deming SL, Shen H, Shen CY, Gammon MD, Blot WJ, Matsuo K, Haiman CA, Khoo US, Iwasaki M, Santella RM, Zhang L, Malin Fair A, Hu Z, Wu PE, Signorello LB, Titus-Ernstoff L, Tajima K, Henderson BE, Chan K, Kasuga Y, Newcomb PA, Zheng H, Cui Y, Wang F, Shieh YL, Iwata H, Le Marchand L, Chan SY, Shrubsole MJ, Trentham-Dietz A, Tsugane S, Garcia-Closas M, Long J, Li C, Shi J, Huang B, Xiang YB, Gao YT, Lu W, Shu XO, Zheng W.  Replication and functional genomic analyses of the breast cancer susceptibility locus at 6q25.1 generalize its importance in women of Chinese, Japanese, and European ancestry.  Cancer Res 2011, 71(4):1344-55

• Dumitrescu L, Carty CL, Taylor K, Schumacher FR, Hindorff LA, Ambite JL, Anderson G, Best LG, Brown-Gentry K, Bůžková P, Carlson CS, Cochran B, Cole SA, Devereux RB, Duggan D, Eaton CB,  Fornage M, Franceschini N, Haessler H, Howard BV, Johnson KC, Laston S, Kolonel LN, Lee ET, MacCluer JW, Manolio TA, Pendergrass SA, Quibrera M, Shohet RV, Wilkens LR, Haiman CA, Le Marchand L, Buyske S, Kooperberg C, North KE, Crawford DC.  Genetic determinants of lipid traits in diverse populations from the Population Architecture using Genomics and Epidemiology (PAGE) Study. PLoS Genet 2011, 7(6): e1002138

• Dorjgochoo T, Gao YT, Chow WH, Shu XO, Yang G, Cai Q, Rothman N, Cai H, Li H, Deng X, Shrubsole MJ, Murff H, Milne G, Zheng W, Dai Q.  Obesity, age, and oxidative stress in middle-aged and older women.  Antioxid Redox Signal 2011, 14(12):2453-60

• Cai Q, Long J, Lu W, Qu S, Wen W, Kang D, Lee JY, Chen K, Shen H, Shen CY, Sung H, Matsuo K, Haiman CA, Khoo US, Ren Z, Iwasaki M, Gu K, Xiang YB, Choi JY, Park SK, Zhang L, Hu Z, Wu PE, Noh DY, Tajima K, Henderson BE, Chan KY, Su F, Kasuga Y, Wang W, Cheng JR, Yoo KY, Lee JY, Zheng H, Liu Y, Shieh YL, Kim SW, Lee JW, Iwata H, Le Marchand L, Chan SY, Xie X, Tsugane S, Lee MH, Wang S, Li G, Levy S, Huang B, Shi J, Delahanty R, Zheng Y, Li C, Gao YT, Shu XO, Zheng W.  Genome-wide association study identifies breast cancer risk variant at 10q21.2: results from the Asia Breast Cancer Consortium.  Hum Mol Genet 2011, 20(24):4991-9

 

Top Ten: 2010

• Signorello LB, Mulvihill JJ, Green DM, Munro HM, Stovall M, Weathers RE, Mertens AC, Whitton JA, Robison LL, Boice JD Jr.  Stillbirth and neonatal death in relation to radiation exposure before conception: a retrospective cohort study . Lancet 2010, 376: 624-630. PMCID: PMC3008402

• Ray WA, Murray KT, Griffin MR, Chung CP, Smalley WE, Hall K, Daugherty JR, Kaltenbach LA, Stein CM.  Outcomes with concurrent use of clopidogrel and proton-pump inhibitors: a cohort study. Ann Intern Med 2010, 152:337-45. PMCID: PMC3176584

• Chen XL, Lu W, Zheng Y, Gu K, Chen Z, Zheng W, Shu XO.  Exercise, tea consumption, and depression among breast cancer survivors.  J Clin Oncol 2010, 28: 991-8. PMCID: PMC2834436

• Friedman DL, Whitton J, Leisenring W, Mertens AC, Hammond S, Stovall M, Donaldson SS, Meadows AT, Robison LL, Neglia JP.  Subsequent neoplasms in 5-year survivors of childhood cancer: the childhood cancer survivor study.  J Natl Cancer Inst 2010, 102:1083-95. PMCID: PMC2907408

• Zheng W, Wen W, Gao YT, Shyr Y, Zheng Y, Long J, Li G, Li C, Gu K, Cai Q, Shu XO, Lu W.  Genetic and clinical predictors for breast cancer risk assessment and stratification among Chinese women.  J Natl Cancer Inst 2010, 102:972-81. PMC2897876

• Nechuta S, Shu XO, Li HL, Yang G, Xiang YB, Cai H, Chow WH, Ji BT, Zhang XL, Wen WQ, Gao YT, Zheng W.  Combined impact of lifestyle-related factors on total and cause-specific mortality among Chinese women: prospective cohort study.  PLoS Med 2010, 7:e1000339. PMCID: PMC2939020

• Modjarrad K, Vermund SH.  Effect of treating co-infections on HIV-1 viral load: a systematic review.  Lancet Infect Dis 2010, 10:455-63. PMCID: PMC3071714

• Ritchie MD, Denny JC, Crawford DC, Ramirez AH, Weiner JB, Pulley JM, Basford MA, Brown-Gentry K, Balser JR, Masys DR, Haines JL, Roden DM. Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record.  Am J Hum Genet 2010, 86:560-72. PMCID: PMC2850440

• Jackson JC, Girard TD, Gordon SM, Thompson JL, Shintani AK, Thomason JWW, Pun BT, Canonico AE, Dunn JG, Bernard GR, Dittus RS, Ely EW. Long-term cognitive and psychological outcomes in the Awakening and Breathing Controlled Trial.  Am J Respir Crit Care Med 2010, 182:183-91. PMCID: PMC2913233

• Long J, Cai QY, Shu XO, Qu S, Li C, Zheng Y, Gu K, Wang WJ, Xiang YB, Cheng JR, Chen K, Zhang L, Zheng H, Shen CY, Huang CS, Hou MF, Shen HB, Hu Z, Wang F, Deming SL, Kelley MC, Shrubsole MJ, Khoo US, Chan KYK, Chan SY, Haiman CA, Henderson BE, LeMarchand L, Iwasaki M, Kasuga Y, Tsugane S, Matsuo K, Tajima K, Iwata H, Huang B, Shi J, Li GL, Wen WQ, Gao YT, Lu W, Zheng W.  Identification of a functional genetic variant at 16q12.1 for breast cancer risk: results from the Asia Breast Cancer Consortium.  PLoS Genet 2010, 6:e1001002. PMCID: PMC2891809

VEC faculty investigators in bold