Current Members
-
Jim Cassat
Associate Professor of Pediatrics; Pathology, Microbiology, and Immunology; and Biomedical EngineeringDivision of Pediatric Infectious DiseasesClinic Phone615-322-2250Lab AddressMedical Center North1161 21st Ave SouthRoom / SuiteA3207NashvilleTennessee37232Jim was born and raised in Little Rock, Arkansas. After completing undergraduate studies and medical school at the University of Arkansas, Jim moved onto Music City for a residency in Pediatrics at Vanderbilt, followed by a fellowship in Pediatric Infectious Diseases. Jim joined Vanderbilt faculty in July 2014.
Clinical Information
Osteomyelitis, Staphylococcus aureus pathogenesis, pediatric infectious diseases
Research Information
Host-pathogen interactions during musculoskeletal infection, bone biology, osteoimmunology, Staphylococcus aureus pathogenesis, Salmonella pathogenesis, antibiotic tolerance
-
Juan was born in Mexico City and earned his B.S. in Biochemistry from the University of Texas at Austin. He started his graduate work in Austin with Marvin Whiteley and moved with his lab to Georgia Tech, where he obtained his PhD. His work focused on the development of tools for characterizing the spatial structure of microbial communities within the context of infectious diseases. In 2022, Juan started his postdoctoral work in a joint venture with the Cassat and Skaar lab at the Vanderbilt Institute for Infection, Immunology and Inflammation. His project incorporates quantitative imaging, clinical samples and single cells assays to answer basic questions about host-pathogen interactions in the gut. He is an avid cyclist, live music enthusiast and is working towards developing a world-class taco experience from his kitchen.
-
Lab AddressMedical Center North1161 21st Ave SouthRoom / SuiteA3207NashvilleTennessee37232
Jacob is a Biochemistry and Molecular Biology graduate from Belmont University in Nashville, TN. During his undergraduate years, his research experiences covered antioxidant degradation and organic synthesis of amino acid analogs. Jacob joined the lab as Research Assistant in the Summer of 2016 and then left to pursue his master's degree from the Philadelphia College of Osteopathic medicine in 2019. He returned to the lab in 2022 and now serves as our fearless Lab Manager!
-
Kara Eichelberger
Postdoctoral FellowDivision of Pediatric Infectious DiseasesLab Phone615-936-6494Office AddressMedical Center North1161 21st Ave SouthRoom / SuiteA3207NashvilleTennessee37232Kara is from Whitehall, PA and earned a B.S. in Biology from Susquehanna University. She received her Ph.D. in Microbiology and Immunology working in the laboratory of Dr. William Goldman at the University of North Carolina at Chapel Hill, where she studied Yersinia pestis interactions with host cells during primary pneumonic plague. Kara joined the Cassat lab in 2020 as a postdoctoral research fellow in the Division of Pediatric Infectious Disease. Her project seeks to understand the consequences of co-infection on osteomyelitis disease progression. In her free time, Kara enjoys running, reading, and watching UNC basketball (go Heels!!).
-
Medical Center North1161 21st Ave SouthRoom / SuiteA3207NashvilleTennessee37232
Brittney attended the University of South Florida where she earned a B.S. in Microbiology and then a Ph.D. in Cell and Molecular Biology. Her Ph.D work was done in the laboratory of Dr. Les Shaw where she studied the transcriptional regulation of Staphylococcus aureus secreted proteases, as well as how these secreted proteases regulate disease progression via their modulation of virulence factor stability. In Spring 2020, Brittney joined the Cassat lab as a postdoctoral research fellow where she is working to understand the mechanisms S. aureus uses to withstand antibiotic treatment in an osteomyelitis infection. Outside of the lab, Brittney enjoys hiking and biking.
-
Clara was born and raised in Toronto, Canada, and attended NYU for her undergraduate studies, where she double majored in Biochemistry and Classics. She began her research journey at The Rockefeller University working under Dr. Charles Rice, before moving to NYU Langone as a founding member of the Dittmann Laboratory. She joined the Vanderbilt MSTP in 2019. In the Cassat Lab, her research focuses on the role of RANKL signaling in regulating the antibacterial response in monocytes. In her free time, Clara loves working out, cooking for a crowd, and playing with her cat, Fig Blossom.
-
Sana is a Nashville native and undergraduate student at Vanderbilt University double majoring in Medicine, Health and Society and Molecular and Cellular Biology. As an intern, her research projects have spanned from studying Staphylococcus aureus infection in bone marrow macrophages and osteoclasts to optimizing cell line and 3D organoid models of Salmonella infection in the small intestine. In her free time, she likes to find new hiking spots and cook traditional Kurdish foods with her family.
-
Logan is originally from Hudsonville, MI and earned a B.S. in Biology and Philosophy from Wheaton College (IL). After a short time in industry microbiology, Logan worked as technician for four years in the lab of Dr. Virginia Miller at the University of North Carolina Chapel Hill where he studied the pathogenesis of Klebsiella pneumoniae. In the Cassat Lab, Logan is investigating how nutrients and analytes shape the host-microbe interface in the context of Staphylococcus aureus bone infection. In his free time, Logan enjoys spending time with his wife, running with his dog, and rock climbing.
-
Jia is from Memphis, TN and earned a B.A. in Molecular Biology from Colorado College. After graduation, she pursued a year of postbac research at the University of Rochester studying antimicrobial resistance in ESKAPE pathogens. Jia joined IGP the fall of 2022. In the Cassat Lab, she studies the the genetic and host factors that contribute to antibiotic tolerance of S. aureus. In her free time, she likes to do art and watch TV.
-
Andrew hails from Monument, CO and earned B.S. in Microbiology from the University of Michigan. As an undergraduate, he studied the role of secondary metabolites during C. difficile infection. He then spent two years at The Rockefeller University studying the impacts of Huntington’s Disease during neurogenesis. In 2024, Andrew joined the Cassat Lab where he is studying mechanisms of antibiotic tolerance and investigating phage contributions to Staphylococcus aureus pathogenesis and persistence. Outside of the lab, Andrew is an avid Colorado sports fan and spends his free time cycling, hiking, and making his own cocktails.
-
Nico Podar
Undergraduate ResearcherVanderbilt UniversityNico is from Oak Ridge, TN and is an undergraduate student at Vanderbilt studying Biomedical Engineering. His first exposure to research was at ORNL, where he studied the evolution of oral microbes as well as the genomics of the actinomycosis-causing bacterium Schaalia odontolytica. In the Cassat Lab, he works on understanding the genetic mechanisms of Staphylococcus aureus virulence enhancement by Candida albicans during co-infection. In his free time, Nico enjoys cooking, rock climbing, and playing the piano.
Alumni
-
Jenna Petronglo
Graduate Student, Department of Pathology, Microbiology, and Immunology615-936-8476Lab AddressLight Hall2215-B Garland AveRoom / Suite1035NashvilleTennessee37232Jenna attended Fordham University where she majored in Biological Sciences and completed a research thesis on the ecology of the black-legged tick, the major vector of Lyme disease. After graduating in 2014, she worked as a research technician at The Albert Einstein College of Medicine and assisted in projects studying Huntington's disease. She joined the IGP in 2017 and the Cassat lab in 2018. Her project focused on how inflammation generated during the innate immune response to S. aureus osteomyelitis affects osteoclast differentiation and function. Jenna successfully defended her dissertation in 2023 and is currently a postdoctoral fellow in the laboratory of Dr. Erica Korb at UPenn.
-
Casey Butrico
Graduate Student, Department of Pathology, Microbiology, and ImmunologyLab Social Chair615-936-8476Lab AddressLight Hall2215-B Garland AveRoom / Suite1035NashvilleTennessee37232Casey was a graduate student in the Microbe Host Interactions program. She is originally from New Jersey and received her B.S. in Biology from Gettysburg College. Casey worked at Janssen R&D in the Translational Oncology Disease Area Stronghold before joining the Cassat lab in 2018. Her research focused on S. aureus metabolism and abscess formation during osteomyelitis in the context of comorbid immune-modulating conditions, including diabetes. After successfully defending her dissertation in 2023, Casey joined Kuros Biosciences as a Scientific Affairs Manager.
-
Lab AddressLight Hall2215-B Garland AveRoom / Suite1035NashvilleTennessee37232
Chris is a Nashville native and graduated Davidson College in 2015 where he focused his research on RSV replication and attachment. He came back to Nashville for the Medical Scientist Training Program (MSTP) and switched gears from virology to bacteriology. His project focused on the role of inflammatory signaling in IBD mediated bone loss, as well as the impact of osteo-immunologic crosstalk during intestinal infection. Chris graduated with the M.D. and Ph.D. degrees in 2023 and is currently a Pediatric Resident at Baylor College of Medicine.
-
Lab AddressLight Hall2215-B Garland AveRoom / Suite1035NashvilleTennessee37232
Caleb is from St. Louis, MO, and attended Washington University in St. Louis as a biomedical engineering student. During his time as an undergraduate, his primary research focused on the role of mechanical force in development of the hip joint in a murine model of paralysis. In March 2021, he completed the research portion of Vanderbilt's Medical Scientist Training Program (MSTP). His research project focused on HIF signaling in osteomyelitis a nanoparticle drug delivery. Caleb is currently an Orthopedic Surgery Resident at Washington University in St. Louis.
-
Aimee Potter (Wilde)
Graduate StudentDepartment of Pathology, Microbiology, and ImmunologyLab Phone615-936-8476Lab AddressLight Hall2215-B Garland AveRoom / Suite1035NashvilleTennessee37232Aimee completed her B.S. in Biology at The University of North Carolina at Chapel Hill with minors in Chemistry and History. Aimee joined the Cassat lab with an interest in studying oxygen regulated mediators of virulence in Staphylococcus aureus. She completed an undergraduate honors thesis studying S. aureus in the Richardson lab at Chapel Hill, so she has followed her love of the bug into graduate school! Aimee graduated from the Microbiology and Immunology program in August of 2019, and is pursuing a career in academia with a post doc in the laboratory of Alison Criss at the University of Virginia.
-
Nicole Putnam
Graduate StudentDepartment of Pathology, Microbiology, and ImmunologyLab Phone615-936-8476Lab AddressLight Hall2215-B Garland AveRoom / Suite1035NashvilleTennessee37232Niki is originally from Wisconsin and received her B.S. from the University of Wisconsin-La Crosse. She then earned her Sc.M. in Molecular Microbiology and Immunology from the Johns Hopkins Bloomberg School of Public Health. She joined the lab in 2015 and her research focus is on osteoimmunology in the context of S. aureus osteomyelitis. Niki defended her thesis in the summer of 2019 and then completed a fellowship in clinical microbiology at the NIH. She is currently an Assistant Professor of Pathology at the University of Maryland School of Medicine, where she also serves as the Assistant Director of the Clinical Microbiology Lab.
-
Lab AddressLight Hall2215-B Garland AveRoom / Suite1035NashvilleTennessee37232
Tom hails from Indianapolis, IN and received his bachelor's degree in chemical engineering from the University of Notre Dame. During his time as an undergraduate, his primary research was focused on polymeric thin film membranes for water filtration using size exclusion chromatography. Tom received his PhD in the Chemical Engineering at Vanderbilt and was co-mentored by Dr. Cassat. His project focused on novel delivery strategies to combat bone-dwelling biofilm infections. Tom now works as a research engineer at a small materials company that focuses on the development of innovative materials that eliminate microbes from high-touch surfaces. He works with a team of engineers, physicists, and chemists to improve, implement, and develop light-activated nano-engineered products.
-
Andrew hails from Cincinnati, Ohio, and is a Science Pre-Professional graduate of the University of Notre Dame. His laboratory background includes medical bacteriology and breast cancer cell research. He was also a scholarship quarterback for the Fighting Irish football team, and attended rookie mini-camp with the Cincinnati Bengals. Andrew joined the lab in the Fall of 2015, as a research assistant I and lab manager extraordinaire. He went on to graduate from medical school and is currently an Internal Medicine Resident at the University of Cincinnati.
-
Daniel grew up in the Virginia suburbs of Washington, D.C. and attended Bucknell University as a biomedical engineer. During his undergraduate years, his research included development of nanoparticle dispersion protocols for the National Institute of Standards and Technology as well as biosensor development for markers of traumatic brain injury. He is now a third-year medical student pursuing his interest in research. Outside of academics, Daniel enjoys writing songs, discovering up-and-coming Nashville musicians, and track and field.
-
Light Hall2215-B Garland AveRoom / Suite1035NashvilleTennessee37232
Ian is from St. Louis, MO, and was an undergraduate researcher in the Cassat lab during his time at Vanderbilt University. After graduation, he began work full-time as a research assistant. His research focuses on the role of several key genes in the bone cell response to the hypoxic osteomyelitic environment. In his free time, Ian likes to exercise, eat good food, and daydream about future travels.
-
Lab AddressLight Hall2215-B Garland AveRoom / Suite1035NashvilleTennessee37232
Laura is from Lexington, NC and received a B.A. in Biology from the University of North Carolina at Chapel Hill. As an undergraduate student, she studied SIR2 involvement in the recruitment of condensin to sites of tension in the chromatin in the Bloom lab. After graduation, she worked as a Research Technician II in the lab of Janelle Arthur at UNC-CH investigating how the yersiniabactin high-pathogenicity island of resident E. coli modulates the host response in the context of inflammatory bowel disease (IBD). Laura joined the Cassat lab to study osteoimmunology and host-pathogen interactions in S. aureus osteomyelitis. She has since pursued a career at Covance as a Study Start Up Associate.
-
Viriginia Cruz-Victorio
Research AssistantDepartment of Pathology, Microbiology, and Immunology615-936-8476Lab AddressLight Hall2215-B Garland AveRoom / Suite1035NashvilleTennessee37232Virginia was born in LA, CA but spent most of her life in Nashville. She went to Union College in New York where she received her B.S. in Neuroscience. Her future plans include earning her M.D. and using it to do volunteer work abroad. Outside of the lab, Virginia enjoys camping, hiking, reading, and traveling.
-
Caroline Minton
Research AssistantDivision of Pediatric Infectious DiseasesCaroline graduated from Harding University in her home state of Arkansas with a B.S. in Biology. Following her undergraduate studies, she attended Emory University in Atlanta, GA, and received a Master of Public Health with a concentration in Global Health and Infectious Disease. Caroline now works full-time as a research assistant in the Cassat lab. In her free time, she likes to go running, embroider, and attend (socially-distanced) concerts.