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Johnson KB, Lee CK, Spooner SA, Davison CL, Helmke JS, Weinberg ST. Automated dose-rounding recommendations for pediatric medications. Pediatrics. 2011 Aug;128(128). e422-8.
Abstract
Although pediatric electronic prescribing systems are increasingly being used in pediatric care, many of these systems lack the clinical decision-support infrastructure needed to calculate a safe and effective rounded medication dose. This infrastructure is required to facilitate tailoring of established dosing guidance while maintaining the medication's therapeutic intent.