Research and Training Programs

In collaboration, the Universidade Eduardo Mondlane (UEM) in Mozambique and the Vanderbilt Institute for Global Health (VIGH) have partnered to will establish the Vanderbilt-Mozambique Biomedical Informatics (VM-BMI) training and research program, the first of its kind in Portuguese-speaking (Lusophone) African countries, with a specific focus on HIV. BMI uses computational and information sciences approaches primarily in biology and human health. VM-BMI will have several components.

Building on the success of a pilot program training traditional healers to initiate HIV counseling and testing, the Vanderbilt Institute for Global Health and the University of Witwatersrand have partnered to expand healer-initiated HIV testing and linkage to care in South Africa.The study team will conduct a cluster, randomized, controlled trial comparing healer-initiated HIV counseling and testing to the standard of care in rural South Africa by utilizing an existing and trusted resource — traditional healers.

Under the program, Molemolemo: Building Research Administration Excellence in South Africa, grant administrators from the Vanderbilt Institute for Global facilitate advanced research capacity through training and implementation of a structured grants management course with administrative leaders from Vanderbilt University Medical Center (VUMC). A significant focus and output of the collaboration with Aurum is the in-house development of a structured grants management training course for non-US-based organizations, which includes essential and elective modules. 

Fellowship applications are open for this NIH collaborative research training grant focused on creating a cohort of highly skilled Nigerian biostatisticians with the capacity to lead and supervise high-level biostatistics activities for HIV research studies in West Africa.Focus includes hands-on biostatistics training. Trainees will take biostatistics courses, become members of a team of biostatisticians doing HIV research at Vanderbilt, and will be assigned to HIV research projects using data from Aminu Kano Teaching Hospital (AKTH).

The Vanderbilt Institute for Global Health (VIGH) and Aminu Kano Teaching Hospital (AKTH) in Kano, Nigeria have received a federal grant to study the factors associated with microalbuminuria among participants in an ongoing clinical trial of genetically at-risk HIV-positive adult Nigerians. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) grant will provide $2.2 million over the next four years.

Project Details: NIH Reporter

Human Immunodeficiency Virus (HIV) infection remains a significant public health problem in the United States (US). It is estimated that almost 15% of the 1.17 million people living with HIV (PLWH) in the US are unaware of their HIV status. And despite the existence of highly effective HIV treatment (antiretroviral therapy, ART), only 65% of people living with diagnosed HIV have achieved viral suppression. Similarly, among HIV-negative people eligible for PrEP, only 18% have used PrEP.

Principal Investigator(s):  Martin Were, M.D., M.S. David Wright, Ph.D. 

Excerpt from the article Fogarty awards $3.3M in COVID-19 supplements to support research, training published in Global Health Matters by the Fogarty International Center: 

Principal Investigator(s): Timothy R. Sterling, M.D. Valeria Cavalcanti Rolla, M.D., Ph.D.

Principal Investigator(s):  Carolyn Audet, Ph.D.

Principal Investigator(s):  Kate Clouse, Ph.D., M.P.H.

Principal Investigators: Timothy Sterling, MD Bruno Andrade Thomas Hawn

The West African Ebola outbreak of 2014-2015 exposed the fragility of Sierra Leone’s health system and highlighted the need for further investments to ensure its future capability of responding to a disease outbreak of this magnitude.

Traditional healers, community-based partners with the national health system of South Africa, are exposed to patient blood an average of 1,500 times during their careers due to the practice of delivering herbal remedies via herbs rubbed into dozens of sub-cutaneous cuts. The purpose of this proposal is to compare two implementation strategies to increase consistent use of PPE: (1) a health care worker provided training program followed by 3 educational outreach and coaching visits at the healer's place of practice vs.

The project connects Vanderbilt researchers across disciplines in order to understand how often people living with HIV move within or outside of the state, and if this mobility is associated with HIV outcomes.

In South Africa, HIV testing has been undermined by HIV stigma, distrust in the allopathic health system, a preference for traditional medicine, and distance to the health facility. South Africa has made progress towards their 90-90-90 goals, yet a substantial proportion of the population do not test regularly; only 33.9% of adults in rural Mpumalanga (our study site) underwent HIV testing in the past year.

The UNZA-Vanderbilt Training Partnership for HIV-Nutrition-Metabolic Research (UVP-1) and the UNZA-Vanderbilt Partnership for HIV-NCD Research (UVP-2) continue a longstanding training collaboration between the University of Zambia School of Medicine/University Teaching Hospital (UNZA/UTH), Vanderbilt University (VU) and the Vanderbilt Institute for Global Health (VIGH).

The Vanderbilt-Nigeria Building Research Capacity in HIV/Non-communicable Diseases (V-BRCH) Program builds capacity of Nigerian investigators to successfully initiate and implement high-quality clinical trials in HIV-associated non-communicable diseases.

Principal Investigator(s): William Wester, M.D., M.P.H.