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Surgical Technique: Closed Reduction and Percutaneous Pinning of Posterolaterally Displaced Supracondylar Humerus Fractures
Prusick, Vincent W. MDa; Gibian, Joseph T. BSb; Ross, Kirsten E. MDa; Moore-Lotridge, Stephanie N. PhDa; Rees, Andrew B. BSa; Mencio, Gregory A. MDa,c; Stutz, Christopher M. MDd; Schoenecker, Jonathan G. MD, PhDa,e,f,c
Pediatric Variants of the Transolecranon Fracture Dislocation: Recognition and Tension Band Fixation: Report of 3 Cases
Author links open overlay panelMatthew A.ButlerMDJeffrey E.MartusMDJonathan G.SchoeneckerMD, PhD
Internal Rotation Stress Testing Improves Radiographic Outcomes of Type 3 Supracondylar Humerus Fractures
Jennifer M Bauer 1, Christopher M Stutz 2, Jonathan G Schoenecker 1, Steven A Lovejoy 1, Gregory A Mencio 1, Jeffrey E Martus 1
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Baker CE, Moore-Lotridge SN, Hysong AA, Posey SL, Robinette JP, Blum DM, Benvenuti MA, Cole HA, Egawa S, Okawa A, Saito M, McCarthy JR, Nyman JS, Yuasa M, Schoenecker JG. Bone Fracture Acute Phase Response- A Unifying Theory of Clinical and Scientific Implications. Clinical Reviews in Bone and Mineral Metabolism 2018 Dec. https://doi.org/10.1007/s12018-018-9256-x
Yuasa M, Mignemi NA, Barnett JV, Cates JM, Obremskey W, Bible J, Nyman JS, Okawa A, Yoshii T, Schwartz HS, Flick M, Degen J, Schoenecker JG. Fibrin is dispensable for fracture healing and fibrinolysis is essential for fracture repair and prevention of heterotopic ossification. J Clin Invest. 2015 Aug 3; 125(8):3117-31. PMID: 26214526
***This manuscript was featured in Fibrinolysis as a Target to Enhance Fracture Healing, N Engl J Med. 2015 Oct 29;373 - PMID: 26510027
- JCI - Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification
- VUMC study shifts thinking on how bone fractures heal | VUMC Reporter | Vanderbilt University
- Broken Bones Don't Heal Like Doctors Thought They Did; Fibrin's Real Role In Wound Healing (medicaldaily.com)
- Fibrinolysis as a Target to Enhance Fracture Healing | NEJM
- The most popular research stories of 2015 | VUMC Reporter | Vanderbilt University
Yuasa M, Mignemi NA, Barnett JV, Cates JM, Nyman JS, Okawa A, Yoshii A, Schwartz H, Schoenecker JG The Temporal and Spatial Development of Vascularity in a Healing Displaced Fracture. Bone. 2014 Oct;67:208-21. doi: 10.1016/j.bone.2014.07.002. Epub 2014 Jul 10 (Cover of Journal – October 2014) – PMID 25016962 –
O’Neill K, Stutz C, Mignemi N, Cole HA, Murry MR, Nyman JS, Hamm H, Schoenecker JG Fracture Healing in Protease-Activated Receptor -2 Deficient Mice. Journal of Orthopaedic Research 2012 Aug;30(8) PMID:22247070.
Micro-computed tomography assessment of the progression of fracture healing in mice - ScienceDirect
Micro-computed tomography assessment of the progression of fracture healing in mice
Author links open overlay panelKevin R.O'NeillaChristopher M.StutzaNicholas A.MignemiabMichael C.BurnsfMatthew R.MurryaJeffry S.NymanacgJonathan G.Schoeneckerabcde
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Mignemi NA, Yuasa M, Baker CE, Moore SN, Ihejirika RC, Oelsner WK, Wallace CS, Yoshii T, Okawa A, Revenko AS, MacLeod AR, Bhattacharjee G, Barnett JV, Schwartz HS, Degen JL, Flick MJ, Cates JM, Schoenecker JG. Plasmin Prevents Dystrophic Calcification After Muscle Injury. J Bone Miner Res. 2017 Feb;32(2):294-308. doi: 10.1002/jbmr.2973. Epub 2016 Dec 5. PubMed PMID: 27530373.
- From Osteoporosis to Heterotopic Ossification: Plasmin Keeps Hydroxyapatite Where It Should Be - Vanderbilt Discover (vumc.org)
- Plasmin Prevents Dystrophic Calcification After Muscle Injury - Mignemi - 2017 - Journal of Bone and Mineral Research - Wiley Online Library
- Plasmin prevents muscle ‘hardening’ after injury: study | VUMC Reporter | Vanderbilt University
Moore-Lotridge SN, Li Q, Gibson BHY, Martin JT, Hawley GD, Arnold TH, Saito M, Tannouri S, Schwartz HS, Gumina RJ, Cates JMM, Uitto J, Schoenecker JG. Trauma-Induced Nanohydroxyapatite Deposition in Skeletal Muscle is Sufficient to Drive Heterotopic Ossification. Calcif Tissue Int. 2019 Apr;104(4):411-425. doi: 10.1007/s00223-018-0502-5. Epub 2018 Dec 4. PubMed PMID: 30515544; PubMed Central PMCID: PMC6437294.
Keeping bone in its place | VUMC Reporter | Vanderbilt University
Moore-Lotridge, SN., Ihejirika, R., Gibson, BHY., Posey, SL., Mignemi, NA., Cole, HA., Hawley, GD., Uppuganti, S., Nyman, JS., Schoenecker, JG. Severe injury-induced Osteoporosis and Skeletal Muscle Mineralization: Are these Related Complications? September 2020. Bone Reports. https://doi.org/10.1016/j.bonr.2020.100743
Calcification after severe injury | VUMC Reporter | Vanderbilt University
Moore SN, Hawley GD, Smith EN, Mignemi NA, Ihejirika RC, Yuasa M, Cates JM, Liu X, Schoenecker JG. Validation of a Radiography-Based Quantification Designed to Longitudinally Monitor Soft Tissue Calcification in Skeletal Muscle. PLoS One. 2016;11(7):e0159624. doi: 10.1371/journal.pone.0159624. eCollection 2016. PubMed PMID: 27438007; PubMed Central PMCID: PMC4954695.
Bisphosphonates: from softening water to treating PXE (nih.gov)
Bisphosphonates: from softening water to treating PXE Stephanie N Moore,1,2 S Bobo Tanner,3 and Jonathan G Schoenecker1
Novel preclinical murine model of trauma-induced elbow stiffness - PubMed (nih.gov)
Moore-Lotridge SN, Oelsner WK, Ihejirika Y, Desai MJ, Gebhart SS, Schoenecker JG. Novel preclinical murine model of trauma-induced elbow stiffness. J Exp Orthop. 2018 Sep 18;5(1):36. doi: 10.1186/s40634-018-0155-3. PubMed PMID: 30229498; PubMed Central PMCID: PMC6143496.
Autologous chondrocyte grafting promotes bone formation in the posterolateral spine (nih.gov)
Autologous chondrocyte grafting promotes bone formation in the posterolateral spine
J. Alex Sielatycki, 1 Masanori Saito, 1 , 2 Masato Yuasa, 1 , 2 Stephanie N. Moore‐Lotridge, 1 , 3 Sasidhar Uppuganti, 1 Juan M. Colazo, 4 Alexander A. Hysong, 4 J. Patton Robinette, 4 Atsushi Okawa, 2 Toshitaka Yoshii, 2 Herbert S. Schwartz, 1 Jeffry S. Nyman, 1 , 5 , 6 , 7 and Jonathan G. Schoenecker 1 , 3 , 8 , 9
Autologous Chondrocyte Grafting Promotes Bone Formation in the Posterolateral Spine (vanderbilt.edu)
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Cole HA, Yuasa M, Hawley G, Cates JM, Nyman JS, Schoenecker JG. Differential Development of the Distal and Proximal Femoral Epiphysis and Physis in Mice. Bone. 2012 Oct 15, PMID:23079139
Cole HA, Ohba T, Nyman JS, Haro H, Cates JM, Flick MJ, Degen JL, Schoenecker JG. Fibrin accumulation secondary to loss of plasmin-mediated fibrinolysis drives inflammatory osteoporosis. Arthritis Rheumatol. 2014 Aug;66(8):2222-33. doi: 10.1002/art.38639 PMID – 24664548
Schoenecker JG, Mignemi N, Stutz C, Liu Q, Edwards J, Lynch C, Holt G, Schwartz H, Mencio G, Hamm H. Therapeutic aprotinin stimulates osteoblast proliferation but inhibits differentiation and bone matrix mineralization. Spine. 35(9):1008-16, 2010 PMID:20407341
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Halverson S, Martus J, Lovejoy S, Mencio G, Schoenecker JG Leptin Elevation as a Risk Factor for Slipped Capital Femoral Epiphysis Independent of Obesity Status. JBJS. 2017 May 99(10) 865-872. PMID: 28509827
A Deeper Look at SCFE and Obesity - Vanderbilt Discover (vumc.org)
Taussig MD, Powell KP, et al., Schoenecker JG, Prevalence of Hypertension in Pediatric Tibia Vara and Slipped Capital Femoral Epiphysis J Pediatr Orthop. 2015 PMID: 26090984
Highlights from our work on Fracture Repair in the Laboratory:
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Micro-Computed Tomography Derived Anisotropy Detects Tumor Provoked Deviations in Bone in an Orthotopic Osteosarcoma Murine Model
Heather A. Cole ,Tetsuro Ohba ,Jiro Ichikawa,Jeffry S. Nyman,Justin M. M. Cates,Hirotaka Haro,Herbert S. Schwartz,Jonathan G. Schoenecker
Quantifying intra‐osseous growth of osteosarcoma in a murine model with radiographic analysis
Heather A. Cole, Jiro Ichikawa, Daniel C. Colvin, Lynda O'Rear, Jonathan G. Schoenecker