Jeffrey Tosoian, MD, MPH
Medical School: Johns Hopkins University School of Medicine
Residency: Johns Hopkins Medical Institutions
Fellowship: University of Michigan, Urologic Oncology and Translational Cancer Research
Clinical Interests: Elevated PSA, Prostate Cancer, Kidney Cancer, Bladder Cancer, Testis Cancer
Dr. Tosoian specializes in the early diagnosis and management of urologic cancers. In addition to his role as a clinician and surgeon, he is a recognized leader in clinical and translational prostate cancer research. His early research demonstrated the safety of monitoring lower-risk prostate cancers on active surveillance, allowing appropriately selected patients to delay or avoid treatment altogether. His ongoing research has led to the development of new, non-invasive tools to guide cancer diagnosis and management. Dr. Tosoian leads the Prostate Cancer Risk Clinic, a clinical program for informed early screening in patients with a strong family history or known genetic mutation associated with prostate cancer.
Highlighted Publications
Tosoian JJ, Penson DF, Chinnaiyan AM. A Pragmatic Approach to Prostate Cancer Screening. JAMA. 2024 May;331(17):1448-1450. doi: 10.1001/jama.2024.4089. PMID: 38581253.
Tosoian JJ, Zhang Y, Xiao L, Xie C, Samora NL, Niknafs YS, Chopra Z, Siddiqui J, Zheng H, Herron G, Vaishampayan N, Robinson HS, Arivoli K, Trock BJ, Ross AE, Morgan TM, Palapattu GS, Salami SS, Kunju LP, Tomlins SA, Sokoll LJ, Chan DW, Srivastava S, Feng Z, Sanda MG, Zheng Y, Wei JT, Chinnaiyan AM; EDRN-PCA3 Study Group. Development and Validation of an 18-Gene Urine Test for High-Grade Prostate Cancer. JAMA Oncol. 2024 Jun;10(6):726-736. doi: 10.1001/jamaoncol.2024.0455. PMID: 38635241.
Robinson HS, Lee SS, Barocas DA, Tosoian JJ. Evaluation of blood and urine based biomarkers for detection of clinically-significant prostate cancer. Prostate Cancer Prostatic Dis. 2024 Jun 10. doi: 10.1038/s41391-024-00840-0. Online ahead of print. PMID: 38858447
Clinical Validation of MyProstateScore 2.0 Testing Using First-Catch, Non-Digital Rectal Examination Urine. Tosoian JJ, Zhang Y, Meyers JI, Heaton S, Siddiqui J, Xiao L, Assani KD, Barocas DA, Ross AE, Chopra Z, Herron GC, Edelson JA, Graham NJ, Singhal U, Salami SS, Morgan TM, Palapattu GS, Wei JT, Chinnaiyan AM.J Urol. 2025 Jan 21:101097JU0000000000004421. doi: 10.1097/JU.0000000000004421. Online ahead of print.PMID: 39836866