The fields of infection biology, immunobiology and inflammation research is varied and ever-expanding. Researchers the world over are making discoveries that contribute greatly to our collective understanding of health and disease. VI4 is committed to providing our members, students, and community resources to aid in knowledge-building in these core VI4 research areas. Please check out our current curated recommended reading list below from scientists across the country.
Recommended Reading - August 8th, 2023
VI4 Curation Team
- The enteric nervous system relays psychological stress to intestinal inflammation. Schneider K, et al. in Cell, May 5, 2023
- Viriforms—A New Category of Classifiable Virus-Derived Genetic Elements. Kuhn J & Koonin E. in Biomolecules, February 13, 2023
- De novo evolution of macroscopic multicellularity. Bozdag G. O, et al. in Nature, May 10, 2023
- Droplet Tn-Seq identifies the primary secretion mechanism for yersiniabactin in Yersinia pestis. Price, S, et al. in EMBO Reports, July 28, 2023
- Ectocytosis renders T cell receptor signaling self-limiting at the immune synapse. Stinchcombe J, et al. in Science, May 23, 2023

Recommended Reading - July 9th, 2023
VI4 Curation Team
- Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections. Buckley, P et al. in Cell Host & Mircobe, May 10, 2023
- Neutrophil metabolomics in severe COVID-19 reveal GAPDH as a suppressor of neutrophil extracellular trap formation. Li Y, et al. in Nature Communications, May 5, 2023
- Age-induced alterations of granulopoiesis generate atypical neutrophils that aggravate stroke pathology . Gullotta G, et al. in Nature Immunology, May 15, 2023
- Infection leaves a genetic and functional mark on the gut population of a commensal bacterium. Tawk C, et al. in Cell Host & Microbe, May 10, 2023
- Mirusviruses link herpesviruses to giant viruses. Gaia M, et al. in Nature, April 19, 2023

Recommended Reading - June 4th, 2023
VI4 Curation Team
- Role of Caspases and Gasdermin A during HSV-1 Infection in Mice. Li L, et al. in Viruses, September 13, 2022
- S+C121:C124tunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes. Culemann S, et al. in Journal of Experimental Medicine, March 28, 2023
- Profiling the human intestinal environment under physiological conditions. Shalon D, Et al. in Nature, May 10, 2023
- Exogenously Scavenged and Endogenously Synthesized Heme Are Differentially Utilized by Mycobacterium tuberculosis. Donegan R, et al. in Microbiology Spectrum, September 28, 2022
- Spatial transcriptome uncovers rich coordination of metabolism in E. coli K12 biofilm. Wang T, et al. in Nature Chemical Biology, April 13, 2023

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Recommended Reading - May 8th, 2023
VI4 Curation Team
- Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis. Weindel C, et al. in Cell, August 18, 2022
- CTCF mediates CD8+ effector differentiation through dynamic redistribution and genomic reorganization. Liu J, et al. in Journal of Experimental Medicine, April 23, 2023
- Exploring Masses and Internal Mass Distributions of Single Carboxysomes in Free Solution Using Fluorescence and Interferometric Scattering in an Anti-Brownian Trap. Lavania A, et al. in The Journal of Physical Chemistry B, October 25, 2022
- STAT3 regulates CD8+ T cell differentiation and functions in cancer and acute infection. Sun Q, et al. in Journal of Experimental Medicine, April 3, 2023
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins. Oh C, et al. in Cell Reports, November 22, 2022

Recommended Reading - April 16th, 2023
VI4 Curation Team
- Coordination of bacterial cell wall and outer membrane biosynthesis. Hummels K, et al. in Nature, March 1, 2023
- Immune landscape in invasive ductal and lobular breast cancer reveals a divergent macrophage-driven microenvironment. Onkar S, et al. in Nature Cancer, March 16, 2023
- SARS-CoV-2 Omicron (B.1.1.529) shows minimal neurotropism in a double-humanized mouse model. Alves, RPdS et al. in Antiviral Research, April 1, 2023
- Glycogen Metabolism in Candida albicans Impacts Fitness and Virulence during Vulvovaginal and Invasive Candidiasis. Miao, J et al. in mBio, February 22, 2023
- GPX4 regulates cellular necrosis and host resistance in Mycobacterium tuberculosis infection. Amaral E, et al. in Journal of Experimental Medicine, September 7, 2022

Recommended Reading - March 5th, 2023
VI4 Curation Team
- CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor. Prokhnevska N, et al. in Immunity, December 21, 2022
- Bacterial droplet-based single-cell RNA-seq reveals antibiotic-associated heterogeneous cellular states. Ma P, et al. in Cell, February 16, 2023
- Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks. Amato K, et al. in Nature Communications, June 14, 2022
- The maternal prenatal and offspring early-life gut microbiome of childhood asthma phenotypes. Lee-Sarwar K, et al. in Allergy, September 15, 2022
- A cytoskeletal vortex drives phage nucleus rotation during jumbo phage replication in E. coli. Birkholz E, et al. in Cell Reports, August 16, 2022

Recommended Reading - February 5th, 2023
VI4 Curation Team
- Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation. Hata M, et al. in Science, January 6, 2023
- Functional T cells are capable of supernumerary cell division and longevity. Soerens A, et al. in Nature, December 5, 2022
- Chlamydia repurposes the actin-binding protein EPS8 to disassemble epithelial tight junctions and promote infection. Dolat L, et al. in Cell Host & Microbe, December 14, 2022
- Gut colonization by Proteobacteria alters host metabolism and modulates cocaine neurobehavioral responses. Cuesta S, et al. in Cell Host & Microbe, November 9, 2022
- Fetal and maternal NLRP3 signaling is required for preterm labor and birth. Motomura K, et al. in The Journal of Clinical Investigation Insights, August 22, 2022

Recommended Reading - January 15th, 2023
VI4 Curation Team
- Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus. Mackensen A, et al. in Nature Medicine, September 15, 2022
- Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses. Hagan T, et al. in Nature Immunology, October 21, 2022
- Engineered cell entry links receptor biology with single-cell genomics. Yu B, et al. in Cell, December 22, 2022
- Mycobiota and diet-derived fungal xenosiderophores promote Salmonella gastrointestinal colonization. Santus W, et al. in Nature Microbiology, November 21, 2022
- Epithelial HNF4A shapes the intraepithelial lymphocyte compartment via direct regulation of immune signaling molecules. Lei X, et al. in Journal of Experimental Medicine, July 6, 2022

Recommended Reading - December 11, 2022
VI4 Curation Team
- Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes. Ataide M, et al. in Immunity, October 11, 2022
- Gut bacterial nutrient preferences quantified in vivo. Zeng X, et al. in Cell Reports, September 1, 2022
- Protein Kinase CK2 Controls CD8+ T Cell Effector and Memory Function during Infection. Yang W, et al. in The Journal of Immunology, September 1, 2022
- Design, construction, and in vivo augmentation of a complex gut microbiome. Cheng A, et al in Cell, September 15, 2022
- Actin cytoskeleton remodeling primes RIG-I-like receptor activation. Acharya D, et al. in Cell, September 15, 2022

Recommended Reading - November 6th, 2022
VI4 Curation Team
- TCF-1 promotes chromatin interactions across topologically associating domains in T cell progenitors. Wang W, et al. in Nature Immunology, June 20, 2022
- Induced pluripotent stem cells display a distinct set of MHC I-associated peptides shared by human cancers. Aavaloaei A, et al. in Cell Reports, August 16, 2022
- Evolution of immune genes is associated with the Black Death. Klunk J, et al. in Nature, October 19, 2022
- Neutrophil Recruitment in Pneumococcal Pneumonia. Palmer C & Kimmey J in Frontiers in Cellular and Infection Microbiology, May 13, 2022
- A dissemination-prone morphotype enhances extrapulmonary organ entry by Cryptococcus neoformans. Denham S, et al. in Cell Host & Microbe, September 12, 2022
