The fields of infection biology, immunobiology and inflammation research is varied and ever-expanding. Researchers the world over are making discoveries that contribute greatly to our collective understanding of health and disease. VI4 is committed to providing our members, students, and community resources to aid in knowledge-building in these core VI4 research areas. Please check out our current curated recommended reading list below from scientists across the country!
Recommended Reading - October 13th, 2019
- Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial. Voorwerk L, et al in Nature, May 13, 2019
- Human Influenza A Virus Hemagglutinin Glycan Evolution Follows a Temporal Pattern to a Glycan Limit. Yewdell JW, Altman MO, et al in American Society for Microbiology, April 1, 2019
- Microbial Exposure Enhances Immunity to Pathogens Recognized by TLR2 but Increases Susceptibility to Cytokine Storm through TLR4 Sensitization. Huggins M, et al in Cell Reports, August 13, 2019
- Altered immunity of laboratory mice in the natural environment is associated with fungal colonization. Yeung F, et al in bioRxiv, August 21, 2019
- Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism. Rekdal V, et al in Science, June 14, 2019
Recommended Reading - September 11th, 2019
- Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes. Cai Q, Jin H, et al in Science, June 8, 2018
- Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma. Amit I, Li H, et al in Cell Press, February 7, 2019
- Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2. Sonnenberg GF, Zhou L, et al in Nature, April 3, 2019
- A c-di-GMP-Based Switch Controls Local Heterogeneity of Extracellular Matrix Synthesis which Is Crucial for Integrity and Morphogenesis of Escherichia coli Macrocolony Biofilms. Hengge R, Serra D in Journal of Molecular Biology, April 4, 2019
- TCR Transgenic Mice Reveal Stepwise, Multi-site Acquisition of the Distinctive Fat-Treg Phenotype. Li C, Mathis D, et all in Cell Press, June 7, 2018
Recommended Reading - June 7th, 2019
- In Vivo Structures of the Helicobacter pylori cag Type IV Secretion System. Chang YW, Jensen G, et al in Cell Reports, April 17, 2019
- p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells. Ihry R, Kaykas A, et al in Nature Medicine, June 11, 2018
- Vesicle-Cloaked Virus Clusters Are Optimal Units for Inter-organismal Viral Transmission. Santiana M, Altan-Bonnet N, et al in Cell Host & Microbe, August 8, 2018
- Unique Patterns and Biogeochemical Relevance of Two-Component Sensing in Marine Bacteria. Held NA, Saito MA, et al in M Systems - ASM, February 5, 2019
- Neutrophils: New insights and open questions. Ley K, Catz SD, et al in Science Immunology, December 7, 2018
Recommended Reading - May 10th, 2019
- Translocation of a gut pathobiont drives autoimmunity in mice and humans. Vieira SM, Goodman AL, Kriegel MA, et al in Science, March 9, 2018
- Structure of the peptidoglycan polymerase RodA resolved by evolutionary coupling analysis. Sjodt M, Rudner DZ, Kruse AC, et al in Nature, April 5, 2018
- Spatial determinants of quorum signaling in a Pseudomonas aeruginosa infection model. Darch S, Shear JB, Whiteley M, et al in PNAS, April 17, 2018
- Bacterial sensors define intracellular free energies for correct enzyme metalation. Osman D, Chivers PT, Robinson NJ, et al in Nature: Chemical Biology, January 28, 2019
- Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers. Gruosso T, Haibe-Kains B, Park M, et al in The Journal of Clinical Investigation, February 12, 2019
Recommended Reading - March 18th, 2019
- Systematic discovery of antiphage defense systems in the microbial pangenome. Doron S, Sorek R, et al in Science, March 2, 2018
- Pulmonary neuroendocrine cells amplify allergic asthma responses. Sui P, Sun X, et al in Science, June 8, 2018
- Peptidoglycan synthesis drives an FtsZ-treadmilling-independent step of cytokinesis. Monteiro JM, Pinho MG, et al in Nature, February 22, 2018
- Immune cell census in murine atherosclerosis: cytometry by time of flight illuminates vascular myeloid cell diversity. Cole JE, Monaco C, et al in Cardiovascular Research, August 1, 2018
- A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein. Tan J, Lanzavecchia, et al in Nature Medicine, March 19, 2018
Recommended Reading - January 7th, 2019
- Salt-responsive gut commensal modulates Th17 axis and disease. Wilck N, Müller DN, et al in Nature, November 15, 2017
- Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors. Routy B, Zitvogel L, et al in Science, November 2, 2017
- Redox-Sensing Under Hypochlorite Stress and Infection Conditions by the Rrf2-Family Repressor HypR in Staphylococcus aureus. Van Loi V, Antelmann H, et al in Antioxidants & Redox Signaling, September 1, 2018
- Dietary and Microbial Oxazoles Induce Intestinal Inflammation by Modulating Aryl Hydrocarbon Receptor Responses. Iyer s, Blumberg RS, et al in Cell, May 17, 2018
- Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis. Cochain C, Zernecke A, et al in Circulation Research, June 8, 2018
Recommended Reading - October 25th, 2018
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Discovery and characterization of a prevalent human gut bacterial enzyme sufficient for the inactivation of a family of plant toxins. Koppel N, Balskus EP, et al in eLife, May 15, 2018
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Staphylococcus aureus clumping factor A is a force-sensitive molecular switch that activates bacterial adhesion. Herman-Bausier P, Dufrêne EF, et al in Proceedings of the National Academy of Sciences, May 2018
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Blocking Neuronal Signaling to Immune Cells Treats Streptococcal Invasive Infection. Pinho-Ribeiro FA, Chiu IM, et al in Cell, May 10, 2018
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Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry. Winkels H, Wolf D, et al in Circulation Research, June 8, 2018
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Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. Shalapour S, Karin M, et al in Nature , November 16, 2017
Recommended Reading - September 27th, 2018
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Identification of a Functionally Unique Family of Penicillin-Binding Proteins. Welsh MA; Taguchi A; et al. in Journal of American Chemical Society, November 28, 2017
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Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia. Baral P; Umans BD; et al. in Nature Medicine, March 5, 2018
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Extensive impact of non-antibiotic drugs on human gut bacteria. Maier L; Pruteanu M; et al. in Nature Medicine, March 19, 2018
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Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients. Gopalakrishnan V; Spencer CN et al. in Science, Jannury 5, 2018
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Functional interrogation and mining of natively paired human VH:VL antibody repertoires. Wang B; DeKosky BJ et al. in Nature Biotechnology, January 8, 2018
Recommended Reading - August 30th, 2018
- Host Nitric Oxide Disrupts Microbial Cell-to-Cell Communication to Inhibit Staphylococcal Virulence. Urbano R; Fang, FC; et al. in Cell Host Microbe, May 9, 2018
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Dietary trehalose enhances virulence of epidemic Clostridium difficile. Collins, J; Britton, A; et al in Nature, January 18, 2018
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Comprehensive skin microbiome analysis reveals the uniqueness of human skin and evidence for phylosymbiosis within the class Mammalia. Ross, AA; Neufeld, JD; et al. in PNAS, June 19, 2018
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Gut microbiome–mediated bile acid metabolism regulates liver cancer via NKT cells. Ma, C; Gretan, TF; et al. in Science, May 25, 2018
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In vivo imaging reveals a tumor-associated macrophage–mediated resistance pathway in anti–PD-1 therapy. Arlauckas, S; Pittet, MJ; et al. in Science Translational Medicine May 10, 2017
