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Bezbradica S., JOYCE S. NKT cells join the two step for inflammasome-independent IL-1β release Cell Reports. 2020 Apr 7;31(31). 107481-1 -- 107481-2.
Abstract
The cytokine interleukin-1β (IL-1β) is critical for antimicrobial defenses; the inflammasome pathway typically controls IL-1β release, but pathogens often evade this pathway. In this issue, Donado et al. (2020) describe an alternative, two-cell model, to instruct inflammasome-independent IL-1β release.