Chengwen Zhou, PhD

Chengwen
Zhou
PhD
Assistant Professor
Neurology

Dr. Chengwen Zhou is an Assistant Professor of Neurology at Vanderbilt University Medical Center specializing in epilepsy research. Since 2018, his research lab has been working on how brain-states influence and trigger seizure onset with homeostatic synaptic plasticity mechanism and recently on sleep-related activity’s roles in pathogenesis of Alzheimer’s diseases. Dr. Zhou is currently a member of the American Epilepsy Society and the Society for Neuroscience, as well as a reviewer for the Journal of Pediatric Neurology.

Dr. Zhou’s work has been actively supported by the NIH, including major awards funding his studies that address how sleep-related brain activity drives up neuron synaptic plasticity and further triggers seizure onset. This work also explores a novel treatment of seizures due to sleep-related activity engagement in seizure onset.   

Dr. Zhou’s appointment at VUMC began in 2011 as a staff scientist, working on idiopathic generalized epilepsy(IGE) with GABAergic receptor mutation. Prior to his position at VUMC, he completed postdoctoral training at Children’s Hospital Boston and Beth Israel Deaconess Medical Center (both with Harvard Medical School), working on the neuroscience of synaptic plasticity, pediatric epilepsy, and seizure disorders. He earned his PhD from University of Alabama at Birmingham (UAB) in 2004 with a focus on Visual Neuroscience, and graduated from Shanghai Institute of Physiology Chinese Academy of Science with a Master’s degree in Neurobiology in 1996. He completed his BS at Southwestern Normal University (China). 

Dr. Zhou’s interests in basic neuroscience and translational medicine focus upon how neuronal activity within the whole brain circuits (both cortical and subcortical circuits on microscopic, mesoscopic and macroscopic levels) interacts to generate collective/emerging brain functions such as memory consolidation and brain disorders such as seizures and cognitive co-morbidity deficits. Particularly he is working on how brain sleep-states intermingle with seizure onset. Using electrophysiological recordings, optogenetic methods, and transgenic mice with GABAergic receptor mutations, he studies intrinsic neuron activity properties, activity-dependent synaptic plasticity in cortical neurons from mouse models for pathogenesis of idiopathic generalized epilepsy (IGE), and explores how epilepsy disorders and memory deficits are generated/evolved. This will lead to developing novel medicines for treating seizures and other cognitive co-morbidities. Recently his research extends to sleep-related activity's roles in pathophysiology and pathogenesis of Alzheimer's disease, using a homeostatic synaptic plasticity mechanism.

Visit Dr. Zhou’s lab website for more information about his research

Holly Westervelt, PhD

Holly
Westervelt
PhD
Associate Professor
Clinical Neurology

Dr. Holly Westervelt is an Associate Professor of Clinical Neurology and Director of Neuropsychological Services for the Department of Neurology at Vanderbilt University Medical Center. She is board certified in clinical neuropsychology through the American Board of Professional Psychology.  As a clinical neuropsychologist, she provides comprehensive cognitive assessment and diagnosis of patients experiencing a wide variety of neurological conditions, with particular expertise in degenerative conditions (e.g., mild cognitive impairment, Alzheimer’s disease, Lewy body disease, frontotemporal dementia), autoimmune conditions such as multiple sclerosis, and metabolic disorders. Dr. Westervelt has served as a supervisor and mentor for medical students, residents, and neuropsychology interns and postdoctoral fellows. 

Dr. Westervelt is a regular editor and reviewer for a number of professional journals and funding institutions, and she was an associate editor for Archives of Clinical Neuropsychology for 8 years. She is a member of several professional organizations, including a fellow for the National Academy of Neuropsychology. 

Prior to her current appointment, Dr. Westervelt was an Associate Professor at the Warren Alpert Medical School of Brown University (Providence, RI), and Neuropsychologist in the Department of Psychiatry at Rhode Island Hospital. She completed a postdoctoral fellowship in Clinical Neuropsychology also at Brown University School of Medicine and Rhode Island Hospital, following an internship at Yale University School of Medicine. Dr. Westervelt earned both her BA (summa cum laude) and PhD from at the University at Albany, State University of New York. 

Dr. Westervelt’s research has covered the intersection of cognition and a variety of neurological conditions such as Huntington’s disease, multiple sclerosis, Lewy body disease, mild cognitive impairment, and other kinds of dementia, as well as psychometric factors affecting assessment, and the impact/utilization of neuropsychological services.

Arthur Walters, MD

Arthur
Walters
MD
Professor
Neurology

Dr. Arthur Walters is currently Professor of Neurology and a member of the Sleep Division at Vanderbilt University Medical Center (VUMC) since 2008.  

In 2008 Dr. Walters was given a distinguished faculty medical license from the state of Tennessee. He also received the 2010 American Academy of Neurology Senior Sleep Science Award for excellence in sleep research. 

Dr. Walters completed his medical degree at Wayne State University, Detroit, MI, his Neurology residency at Downstate Medical Center Brooklyn, NY, and subsequently his Movement Disorders Fellowship at the Neurological Institute, Columbia Presbyterian Medical Center, NY, NY. He served as Assistant and Associate Professor of Neurology at UMDNJ-Robert Wood Johnson Medical School and then as full Professor of Neuroscience at the Seton Hall University School of Graduate Medical Education, both in New Jersey, from 1998-2008. 

Book
Chokroverty S, Hening W, Walters A, eds. Sleep and Movement Disorders, 1st Edition, USA, Butterworth Heinemann, pp 1-546, 2003. Revised edition:  Oxford University Press 2013.

Originally trained in Movement Disorders and secondarily in Sleep Disorders, Dr. Walters has focused his career and research on the sleep-related movement disorders. He co-edited the first book on sleep-related movement disorders in 2003, revised edition 2013. He was chosen by the American Academy of Sleep Medicine to lead the committee for formulating the new diagnostic clinical criteria for the sleep-related movement disorders (International Classification of Sleep Disorders 2005 and 2014) and the committee for formulating the new polysomnographic scoring criteria for the sleep-related movement disorders (The AASM Manual for the Scoring of Sleep and Associated Events 2007).

From 1992-1998 he helped found and was the first chair of the Medical Advisory Board of the Restless Legs Syndrome Foundation (RLSF), a nation-wide support group for RLS patients and their families. He continues as an active member of the board.  From 1993 to 2007 he founded and served as the first chair of the International Restless Legs Syndrome Study Group (IRLSSG), comprised of over 130 physicians and scientists from 17 countries dedicated to research on RLS and Periodic Limb Movements in Sleep. Under his leadership, universal clinical criteria for the diagnosis of RLS were established and the first validated scale for the scoring of RLS severity was created and validated. This scale is now used as the primary outcome measure in all the major pharmaceutical company studies of RLS. He continues as an active member of the executive board of the IRLSSG.

In the academic year 2003-2004 he was named “Researcher of the Year in Medicine” for Seton Hall University, one of 4 such awards given by the University that year for excellence in research in (1) Medicine, (2) The Arts, (3) The Humanities, and (4) the Social and Physical Sciences.

Dr. Walters most recent research interests are in the connection between RLS and hypertension, cardiovascular disease and stroke and also exploration into the hypothesis that RLS may be triggered by inflammation and auto-immune mechanisms as well as by endogenous opioid deficiency. 

Bangalore Vittal, MD

Bangalore
Vittal
MD
Adjunct Associate Professor
Neurology

Dr. Nandakumar Bangalore Vittal is an Adjunct Assistant Professor of Neurology specializing in epilepsy at Vanderbilt University Medical Center. He works regularly with Clinical Neurophysiology Fellows in both inpatient and outpatient settings at VUMC. His work is primarily focused on clinical and hospital consults, while participating in bedside teaching with medical students and residents in these clinical settings. In addition to his clinical and educational roles at VUMC, Dr. Vittal is also an Associate Professor of Neurology at Meharry Medical College and attending neurologist at Nashville General Hospital, where he regularly offers lecture and bedside education. Dr. Vittal is a member of the American Academy of Neurology and the American Epilepsy Society. 

Prior to his current positions, Dr. Vittal was a Clinical Instructor of Neurology in the Epilepsy Division at VUMC, following his completion of a Clinical Neurophysiology Fellowship, also at Vanderbilt. He completed his Neurology residency at the University of Arkansas for Medical Sciences after earning a Master of Science in Biology at Western Kentucky University. He received his medical degree at Bangalore Medical College (India).

Raghu Upender, MD, MBA

Raghu
Upender
MD, MBA
Professor
Neurology

Dr. Upender is a Professor of Neurology and the Medical Director of Vanderbilt Sleep Disorders Center. His clinical, scholarly, and administrative efforts have been centered on the practice and promotion of sleep medicine and sleep health. He has served a 5-year term on the U.S. Coast Guard Medical Advisory Committee. He continues to advocate for sleep health through the American Academy of Sleep Medicine Public Safety Committee. 

He graduated summa cum laude from University of Connecticut in 1990 with a Bachelor of Science degree in Physiology and Neurobiology. He earned his medical degree from University of Connecticut in 1995. During medical school, he received the Howard Hughes Medical Institutes Research Scholarship to conduct research at the NIH. He completed medical internship at the Long Island Jewish Medical Center in 1996. He then completed neurology residency and fellowship in neuromuscular diseases and electromyography at the Washington University in 2000. Upon completion of training, he joined a general neurology practice in Connecticut and later in middle Tennessee. During this time, he pursued his interests in sleep medicine and clinical research and completed numerous clinical trials in the treatment of diabetic neuropathy, post herpetic neuralgia, headache, and insomnia. He joined Vanderbilt Neurology faculty in January of 2011 to focus his efforts in sleep medicine. He received his Master of Business Administration (MBA) degree from Vanderbilt University’s Owen Graduate School of Management in 2016.

Dr. Upender is a diplomate of American Board of Psychiatry and Neurology and holds certification in both Neurology and Sleep Medicine. He is also a diplomate of American Board of Electromyography.

In addition to supervising neurology residents in the neurology clinics and in the hospital, his scholarly pursuits have been focused on the emerging field of occupational sleep medicine. This field aims to understand and mitigate the adverse health and safety risks associated with shift work. His research has focused on developing metrics to quantify fatigue, especially in those engaged in shift work. Measuring fatigue objectively and reliably can allow workers and employers to take appropriate actions to reduce fatigue-related injuries and economic losses. 

Stephanie Leigh Taylor, MD

Stephanie
Leigh
Taylor
MD
Assistant Professor
Clinical Neurology
Residency Assistant Program Director of Continuous Improvement

Faculty Spotlight

Dr. Stephanie Taylor is an Assistant Professor of Neurology at Vanderbilt University Medical Center, specializing in Neuroimmunology and General Neurology. In her clinical roles, she manages patients in outpatient clinics, as well as inpatient Neurology service and consultations in the hospital as well as via teleneurology. She provides education to medical students, residents, and fellows through clinical experience and didactic instruction. 

Prior to her current appointment, Dr. Taylor completed a Multiple Sclerosis Clinical Care Physician Fellowship, awarded by the National Multiple Sclerosis Society, at VUMC. She also completed her Neurology residency at VUMC, serving as Chief Resident her final year. She earned her MD from the Joan C. Edwards School of Medicine at Marshall University, and her BS in Neuroscience from Johns Hopkins University. Throughout undergraduate and medical school, Dr. Taylor worked as a research coordinator with a focus on Multiple Sclerosis.


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Randip S. Taneja, MD

Randip
S.
Taneja
MD
Clinical Director
Intraoperative Monitoring (IOM)
Assistant Professor
Clinical Neurology

Dr. Randy Taneja is an Assistant Professor of Neurology specializing in epilepsy at Vanderbilt University Medical Center. He works regularly with Neurology residents and Clinical Neurophysiology fellows in both inpatient and outpatient settings. In addition to managing epilepsy patients, Dr. Taneja attends to patients and supervises residents in the general neurology clinic and hospital. He is a member of the American Academy of Neurology and the American Epilepsy Society, and is board certified in both Neurology and Epilepsy.

Dr. Taneja serves as the Director of the TeleEEG Service recently launched by the Department of Neurology. As part of the department’s growing teleneurology program, the TeleEEG service allows VUMC physicians to read EEG data for nearly a dozen satellite hospitals in Tennessee and Kentucky, thus providing highly specialized care throughout the region. Highly proficient in information technology, Dr. Taneja also provides key technical support to the department. He aided in the monumental undertaking of launching VUMC’s Epilepsy Monitoring Unit and ICU EEG service upgrade, as well as initiating the TeleEEG services.

In addition to his clinical, educational, and technical roles at VUMC, Dr. Taneja is involved in various epilepsy clinical trials as well as investigational studies regarding the treatment of small fiber neuropathy. He co-authored and edited Essentials of Nerve Conduction Studies (a guide to help physicians and technicians perform nerve conduction tests). He also actively participates in community events, raising awareness for epilepsy and other neurological conditions and coordinating closely with such organizations as the Epilepsy Foundation of Middle and West Tennessee for the annual Walk to End Epilepsy. 

After completing his medical education at Kasturba Medical College in India and Ross University, Dr. Taneja completed his Neurology residency at Cooper University Hospital in New Jersey, where he served as Chief Resident during his final year. This was followed by a fellowship in Clinical Neurophysiology at Vanderbilt University Medical Center, where he remained to work as clinical faculty. 

Kassandra L. Stubblefield, MSN

Kassandra
L.
Stubblefield
MSN
Assistant
Neurology
Lead inpatient APP

Kassandra Stubblefield is currently a nurse practitioner in the Department of Neurology at Vanderbilt University Medical Center (VUMC). In her role, she supports the inpatient neurohospitalist consultation service and provides neurology consultations to Vanderbilt Stallworth Rehabilitation Hospital. 

Kassandra received her bachelor degree from Florida State University with majors in biochemistry and chemical science. She later earned her Master’s of Science in Nursing in 2001 from the Adult Nurse Practitioner program at Vanderbilt University. 

Subramaniam Sriram, MBBS

Subramaniam
Sriram
MBBS
Division Chief
Neuroimmunology
William C. Weaver, III, Professor
Experimental Neurology

Dr Sriram is Professor of Neurology and Immunology and Head of the Neuroimmunology Divsion. He has worked in the field of multiple sclerosis and allied demyelinating disorders his entire professional career.
He received the MBBS from University of Madras, India. He then completed an internship in Internal Medicine at Ford Medical Center in Detroit, Michigan and Neurology residency at Stanford University Medical Center.

He was Acting Assistant Professor of Neurology, Stanford University School of Medicine, Stanford, CA where he completed a Senior Research Associate in the Department of Neurology. He then moved to the University of Vermont College of Medicine where he was Assistant Professor of Neurology first and then promoted to Associate Professor of Neurology.
In 1993 he moved to Nashville, TN and started a Multiple Sclerosis Center at Vanderbilt University Medical Center.
Dr Sriram founded the first comprehensive Multiple Sclerosis Center of the SouthEastern.

The main focus of Dr Srirams laboratory is to examine the immunological factor(s) which are likely involved in recovery of lesions from MS. Dr Srirams laboratory discovered that one particular cytokine, IL-33 is an important player in promoting recovery in animal models of multiple sclerosis. Patients who have stable disease show increased levels of IL-33 in their blood and in the cerebrospinal fluid.
Dr Srirams lab has also found certain novel genes that play a role in the induction of IL-33. In addition certain agents which have been used for multiple sclerosis in the past and since discarded may is likely to be a good candidate for promoting recovery.

Along with Drs Pawate and Bagnato Dr Sriram is interested in developing novel MRI techniques for examining recovery.