FDA Approval of Vaccines and EUA Infographic

FDA Approval of Vaccines and EUA - All vaccines distributed in the USA are under regulation of the FDA. There is a Standard Process that researchers will use to go through clinical trials and vaccine approval. During the COVID-19 pandemic, the FDA utilized a Fast-Track method that helped vaccines be tested more quickly without compromising on safety goals. Additionally, due to the COVID-19 pandemic, the FDA also was granting Emergency Use Authorization (EUA) so that the vaccines could be administered to the public more quickly. It’s important to note that the FDA was working on modernizing clinical trials, including creating guidance for adaptive designs, back in 2018. The COVID-19 pandemic created the need for this “fast-track” to be implemented.... Click the image to the left to continue reading.

Nicole L. Ward, Ph.D.

Nicole
Ward, Ph.D.
Vice Chair for Basic Research, Department of Dermatology
Professor of Dermatology
Professor of Pathology, Microbiology and Immunology

Dr. Ward is a Professor and the Vice-Chair of Basic Research in the Department of Dermatology. She joined the department in January 2022 after working at Case Western Reserve University in Cleveland for more than 18 years.  Dr. Ward completed her undergraduate, graduate and fellowship training in Canada before moving to Cleveland in 2003.  Her active research program is focused on understanding the cellular and molecular pathogenesis of chronic inflammatory skin diseases, like psoriasis and psoriasis-related comorbidities. Her lab specializes in generating and studying unique mouse models of inflammatory skin disease. Her group has published several seminal findings including being the first to show that chronic skin-initiated inflammation can drive the development of cardiovascular disease and that suppressing it reverses disease; and that cutaneous sensory nerve interactions with dendritic cells are critical for eliciting and sustaining psoriasis pathogenesis, thus explaining the cellular mechanisms underlying psoriasis disease remission following skin denervation. Her paradigm shifting work in psoriasis resulted in her being awarded the Eugene M. Farber Lecture at the 2016 Society for Investigative Dermatology meeting. She was the first non-MD, first woman and youngest person to be awarded this honor. In 2019, the American Skin Association acknowledged her scientific contributions with the Research Achievement Award in Psoriasis and in 2022 the National Psoriasis Foundation honored her at their Women Who Lead Commit to Cure Gala. Dr. Ward trains, teaches, and mentors undergraduate, graduate and medical students, residents, post-doctoral fellows, and junior faculty. At any given time, Dr. Ward’s lab is usually found to be surprisingly small. However, it is also often referred to as “small but mighty”. 

MCN
Vanderbilt University Medical Center
1161 Medical Center Drive
Room / Suite
CC3327
Nashville
Tennessee
37232

Dr. Ward's research interests include psoriasis, psoriatic arthritis (PsA), osteogenesis imperfecta (OI), lupus, hidradenitis suppurativa (HS), other inflammatory skin diseases, multi-‘omics, microbiome, and skin disease co-morbidities.

 

Publications on PubMed.gov

nicole.ward@vumc.org

Postdoc Spotlight: Seth Zost, Ph.D.

Seth graduated from the University of Pennsylvania in 2013 with a B.A. in Biochemistry and History and a M.S. in Chemistry. Following graduation, Seth joined the lab of Dr. Scott Hensley at the University of Pennsylvania and studied human antibody responses to influenza A viruses and the viral evasion of pre-existing immunity. Seth defended his PhD in 2018. In the lab, Seth is continuing to study antibody responses against respiratory viruses with special interests in defining conserved sites on viral proteins that are targeted by human antibodies and identifying how prior exposure shapes human antibody responses against viruses like influenza and SARS-CoV-2....Click the image on the left to continue reading.