T cell characteristics associated with toxicity to immune checkpoint blockade in patients with melanoma. Lozano A, et al. in Nature Medicine, January 13, 2022 Bacterial gasdermins reveal an ancient mechanism of cell death. Johnson A, et al.

Dr. Ferguson completed a BA in Human Genetics at Trinity College Dublin, and a PhD in Nutrigenomics at University College Dublin, Ireland, before moving to Philadelphia for postdoctoral training in Cardiovascular Genomics at the University of Pennsylvania. She moved to Nashville to join the faculty at Vanderbilt in October 2014... Click Dr. Ferguson's photo to continue reading.

Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis. Hinrichsen F, et al. in Cell Metabolism, December 7, 2021 Establishment and characterization of stable, diverse, fecal-derived in vitro microbial communities that model the intestinal microbiota. Aranda-Diaz A, et al.

Dr. Patrick earned her Master's degree from the University of Pennsylvania, Biochemistry and Molecular Biophysics, and her M.D./Ph.D. from the University of Texas Southwestern Medical Center. She's an Assistant Professor of Pediatrics Rheumatology at Vanderbilt where her work focuses on identifying and characterizing pathogenic molecular pathways in juvenile idiopathic arthritis and pediatric autoimmune disease.... Click Dr. Patrick's photo to continue reading.

Mapping the cellular origin and early evolution of leukemia in Down syndrome. Wagenblast E, et al. in Science, July 9, 2021 Arthritis flares mediated by tissue-resident memory T cells in the joint. Chang M, et al.

Hepatic stellate cells suppress NK cell-sustained breast cancer dormancy. Bentires-Alj M et al. in Nature, June 2, 2021 Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis. Jul`e A, et al.

We sat down with Dr. Robert Carnahan from the Vanderbilt Vaccine Center to talk about antibody therapeutics and how they can be used in the fight against COVID-19... Click the image to the left to watch!

Lillian Brady, Ph.D. and Kirsty Erickson are part of the Erin Calipari Lab at Vanderbilt University in the Department of Pharmacology. Lillian obtained her PhD from the University of Alabama at Birmingham (UAB) in the Department of Neurobiology. While at UAB, Lillian worked with Dr. Lynn Dobrunz where she studied the role of the dopamine system in the modulation and regulation of inhibitory synaptic transmission and neural circuit function within the hippocampus. Lillian joined Vanderbilt University as an Academic Pathways Postdoctoral Research Fellow in May of 2017 where her research interests include understanding the synaptic physiology, circuit function, and molecular mechanisms that underlie different types of learning behavior. Kirsty graduated from the University of South Dakota in 2016 with a BS in Medical Biology, during which time she studied the role of Ubiquilin-1 in learning and memory. Kirsty came to Vanderbilt in 2017 as a research assistant in the Neul lab, where she investigated the pathogenesis of Rett Syndrome. Now, she joins the Calipari Lab as a graduate student interested in terminal dopamine dynamics that render susceptibility to stimulant use disorder... Click the image on the left to continue reading.

The mRNA vaccine is a new type of vaccine that allows your body to trigger an immune response without using the actual germ to train your immune system. Instead, it trains your immune response using a piece of the virus and will later protect you from getting infected/sick if you encounter the actual virus. Since it is new, here is a list of the generalized ingredients for the mRNA vaccines currently available in the US.... Click the image on the left to learn more!

Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers. Caushi J, et al. in Nature Biotechnology, July 21, 2021 An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancer. Voabil P, et al.